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62篇 您的检索式：作者名="Talegaonkar"

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	题名	作者	年代	出处	被引量
1	Design and development of novel bioadhesive niosomal formulation for the transcorneal delivery of anti-infective agent:In-vitro and ex-vivo investigations显示文摘Gatifloxacin eye drops are frequently used in eye infections.However such formulations have a major drawback i.e.short duration of action and usually require 4e6 times installations daily.A chitosan coated niosomal formulation of gatifloxain was purposed to show a longer retention time on eyes and subsequent reduction in dosing frequency.Vesicles were prepared by solvent injection method using cholesterol and Span-60.An extensive optimization of formulation was done using different ratios of cholesterol,Span-60 and drug,revealed NS60-5(cholesterol:span-6050:50 and drug content of 20 mg)to be the optimized niosome formulation.NS60-5 had shown a highest entrapment efficiency of 64.9±0.66%with particle size 213.2±1.5 nm and zeta potential34.7±2.2 mV.Optimized niosomes were also coated with different concentrations of chitosan and evaluated.Permeation studies had revealed that optimized niosomes(86.77±1.31%)had increased the transcorneal permeation of Gatifloxacin more than two fold than simple drug solution(37.19±1.1%).Longer retention potential of the coated niosomes was further verified by fluorescence microscopy.Study revealed that simple dye solution got easily washed out with in 6 h.The uncoated niosomes(NS60-5)showed a longer retention(more than 6 h),which was further enhanced in case of coated niosomes i.e.CNS60-1(more than 12 h).Antimicrobial studies had shown the better efficacy of CNS60-1(zone of inhibition)when compared to marketed formulation.The final chitosan formulation was found to have shown better ocular tolerability as demonstrated by corneal hydration test histopathology investigations.	Yahaya Zubairu Lalit Mohan Negi Zeenat Iqbal Sushama Talegaonkar	2015	Asian Journal of Pharmaceutical Sciences2015，10，4：	4
2	Development and bioavailability assessment of ramipril nanoemulsion formulation显示文摘	Shafiq S Shakeel F Talegaonkar S	2007	European Journal of Pharmaceutics and Biopharmaeeutie2007，66，2：	1
3	Development and bioavailability assessment of ramipril nanoemulsion formulation显示文摘	Shafiq S Shakeel F Talegaonkar S etal	2007	Eur J Pharm Biopharm2007，66，2：	1
4	Role of CD44 in tumour progression and strategies for targeting显示文摘	Negi LM Talegaonkar S Jaggi M		0，，07：	1
5	Chitosan- sodium alginate nanoparticles as submicroscopic reservoirs for ocular delivery: formulation, optimisation and in vitro cha- racterisation 显示文摘	Motwani SK Chopra S Talegaonkar S	2008	Eur J Pharm Biopharm2008，68，3：	1
6	Drying characteristics of combustible cartridge case显示文摘	SYAL R K TALEGAONKAR S B PESHAVE J R	1995	Chemical En- gineering World1995，30，6：	1
7	Assessment of ocular pharmacokinetics and safety of Ganciclovir loaded nano?formulations显示文摘	AKHTER S TALEGAONKAR S KHAN Z I	2011	J Biomed Nanotechnol2011，7，1：	1
8	Niosomes in sustained and tar- geted drug delivery : some recent advances 显示文摘	Azeem A Anwer MK Talegaonkar S	2009	Drug Target2009，17，9：	1
9	Development and bioavailability assessment of ramipril nanoemulsion formulation显示文摘	Shafiq S Shakeel F Talegaonkar S		0，，2：	1
10	Chi tosan-sodium alginate nanoparticles as submicroscopic reservoirs for ocular delivery: Formulation,optimisation and in vitro charac- terisation显示文摘	MOTWANI S K CHOPRA S TALEGAONKAR S	2008	European Journal of Pharmaeeuties and-Biopharma- ceutics2008，68，3：	1
11	Development and bioavailabilityassessment of ramipril nanoemulsion formulation显示文摘	Shafiq S Shakeel F Talegaonkar S	2007	Eur J Pharm Biopharm2007，66，2：	1
12	Oil based nanocarrier sys-tem for transdermal delivery of ropinirole : a mechanistic, pharmacoki-netic and biochemical investigation 显示文摘	Azeem A Talegaonkar S Negi LM	2012	Int J Pharm2012，422，12：	1
13	Enhanced transdermal drug delivery techniques:an extensive review of patents 显示文摘	Rizwan M Aqil M Talegaonkar S	2011	Recent Pat Drug Deliv Formul2011，3，2：	1
14	A logical approach to optimize the nanostructured lipid carrier system of irinotecan , efficient hybrid design methodology显示文摘	Negi L M Jaggi M Talegaonkar S	2013	Nanotechnology2013，24，01：	1
15	Microemulsion as atool for the trans- dermal delivery of ondansetron for the treatment ofchemotherapy induced nausea and vomiting 显示文摘	Al Abood RM Talegaonkar S Tariq M	2013	Colloids Surf BBiointeifaces2013，101，：	1
16	Chitosan- sodium alginate nanoparticles as submicroscopic reser- voirs for ocular delivery :formulation,optimisation and in vitro cbaracterisation 显示文摘	Motwani SK Chopra S Talegaonkar S	2008	Eur J Pharm Biopharm2008，68，3：	1
17	Drying char-acteristics of combustible cartridge case显示文摘	Syal R K Talegaonkar S B Peshave J R	1995	ChemicalEngineeringWorld1995，30，6：	1
18	Development and bioavailability assessment of rarnipril nanoemulsion formulation显示文摘	Shafiq S Shakeel F Talegaonkar S	2007	European Journal of Pharmaceutics and Biopharmaceutics2007，66，2：	1
19	Microemulsion as atool for the transdermal delivery of ondansetron for the treatment ofchemotherapy induced nausea and vomiting显示文摘	Al Abood RM Talegaonkar S Tariq M	2013	Colloids and SurfacesB Biointeifaces2013，101，：	1
20	Chitosansodium alginate nanoparticles as submicroscopic reservoirs for ocular delivery:formulation, optimisation and in vitro characterization 显示文摘	Motwani S K Chopra S Talegaonkar S	2008	Eur J Pharm Biopharm2008，68，3：	1

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