|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The RppC-AvrRppC NLR-effector interaction mediates the resistance to southern corn rust in maize显示文摘Southern corn rust(SCR),caused by the fungal pathogen Puccinia polysora,is a major threat to maize pro-duction worldwide.Efficient breeding and deployment of resistant hybrids are key to achieving durable control of SCR.Here,we report the molecular cloning and characterization of RppC,which encodes an NLR-type immune receptor and is responsible for a major SCR resistance quantitative trait locus.Further-more,we identified the corresponding avirulence effector,AvrRppC,which is secreted by P.polysora and triggers RppC-mediated resistance.Allelic variation of AvrRppC directly determines the effectiveness of RppC-mediated resistance,indicating that monitoring of AvrRppC variants in the field can guide the rational deployment of RppC-containing hybrids in maize production.Currently,RppC is the most frequently deployed SCR resistance gene in China,and a better understanding of its mode of action is crit-ical for extending its durability. | Ce Deng April Leonard James Cahill Meng Lv Yurong Li Shawn Thatcher Xueying Li Xiaodi Zhao Wenjie Du Zheng Li Huimin Li Victor Llaca Kevin Fengler Lisa Marshall Charlotte Harris Girma Tabor Zhimin Li Zhiqiang Tian Qinghua Yang Yanhui Chen Jihua Tang Xintao Wang Junjie Hao Jianbing Yan Zhibing Lai Xiaohong Fei Weibin Song Jinsheng Lai Xuecai Zhang Guoping Shu Yibo Wang Yuxiao Chang Weiling Zhu Wei Xiong Juan Sun Bailin Li Junqiang Ding | 2022 | Molecular Plant2022，15，5： | 6 |
| 2 | 基于图像处理的个性化建模:从医学扫描到高精度计算模型的转换(英文)显示文摘目的对于生物力学领域的研究者来说,计算仿真技术已成为一种不可或缺的工具。对于这种工具的性能,至关重要的一点在于其有效模拟个性化问题方面的能力。本文将阐述能将三维数字图像(由CT、超声机或MRI扫描仪生成的)直接转换生成高精度计算模型的一种独特的非常有效的方法。方法采用的方法主要涉及:基于扫描的数据生成可输出到商业网格器中的表面模型——这种方法非常费时并且不是很精确,事实上对于复杂拓扑结构的影像数据这种方法很难处理:另外一种更加直接的方法是将几何模型的生成和网格划分一次性完成——这种方法先对感兴趣区域(三维图像分割)进行识别分割,然历直接生成基于一种由定义的边界分割的体素的体网格,这种方法被用来在整个体模型生成四面体和/或六面体单元,从而直接划分网格。结果采用一种基于图像的网格方法来处理问题是非常先进的,也是非常精确有效的。这种基于图像自动生成的网格,其有限元单元模型区域边界正好在等值面上因此其考虑了局部体效应从而能保证局部体素的精确度。结论对影像数据进行网格化是挑战也是机遇,这种与以往方法思想不一样的方法,在很多例子中,获得了更好的结果。这种能简易生成精确模型的方法,对于当前很多数值分析难以处理的问题诸如血液流体和病人个性化假体设计等提供了新的解决方案。 | XIA Ling Rajab Said Philippe Young Gavin Tabor Sam Coward HUANG Jean | 2008 | 医用生物力学2008，23，1： | 4 |
| 3 | Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source显示文摘BACKGROUND The trans-fat containing AMLN(amylin liver non-alcoholic steatohepatitis,NASH)diet has been extensively validated in C57BL/6J mice with or without the Lep^ob/Lep^ob(ob/ob)mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating hallmarks of NASH.Due to a recent ban on trans-fats as food additive,there is a marked need for developing a new diet capable of promoting a compatible level of disease in ob/ob and C57BL/6J mice.AIM To develop a biopsy-confirmed mouse model of NASH based on an obesogenic diet with trans-fat substituted by saturated fat.METHODS Male ob/ob mice were fed AMLN diet or a modified AMLN diet with trans-fat(Primex shortening)substituted by equivalent amounts of palm oil[Gubra amylin NASH,(GAN)diet]for 8,12 and 16 wk.C57BL/6J mice were fed the same diets for 28 wk.AMLN and GAN diets had similar caloric content(40%fat kcal),fructose(22%)and cholesterol(2%)level.RESULTS The GAN diet was more obesogenic compared to the AMLN diet and impaired glucose tolerance.Biopsy-confirmed steatosis,lobular inflammation,hepatocyte ballooning,fibrotic liver lesions and hepatic transcriptome changes were similar in ob/ob mice fed the GAN or AMLN diet.C57BL/6J mice developed a mild to moderate fibrotic NASH phenotype when fed the same diets.CONCLUSION Substitution of Primex with palm oil promotes a similar phenotype of biopsyconfirmed NASH in ob/ob and C57BL/6J mice,making GAN diet-induced obese mouse models suitable for characterizing novel NASH treatments. | Michelle L Boland Denise Oro Kirstine S T■lb■l Sebastian T Thrane Jens Christian Nielsen Taylor S Cohen David E Tabor Fiona Fernandes Andrey Tovchigrechko Sanne S Veidal Paul Warrener Bret R Sellman Jacob Jelsing Michael Feigh Niels Vrang James L Trevaskis Henrik H Hansen | 2019 | World Journal of Gastroenterology2019，25，33： | 3 |
| 4 | The wear of filled polytetrafluoroethylene 显示文摘 | Bahadur S Tabor D | 1984 | Wear1984，94，1： | 2 |
| 5 | Colorectal cancer biomarkers: To be or not to be? Cautionary tales from a road well travelled显示文摘Colorectal cancer(CRC)is the second most common cause of cancer-related death worldwide and places a major economic burden on the global health care system.The time frame for development from premalignant to malignant disease typically spans 10-15 years,and this latent period provides an ideal opportunity for early detection and intervention to improve patient outcomes.Currently,early diagnosis of CRC is hampered by a lack of suitable non-invasive biomarkers that are clinically or economically acceptable for populationbased screening.New blood-based protein biomarkers for early detection of CRC are therefore urgently required.The success of clinical biomarker discovery and validation studies is critically dependent on understanding and adjusting for potential experimental,analytical,and biological factors that can interfere with the robust interpretation of results.In this review we outline some important considerations for research groups undertaking biomarker research with exemplars from our studies.Implementation of experimental strategies to minimise the potential effects of these problems will facilitate the identification of panels of biomarkers with the sensitivity and specificity required for the development of successful tests for the early detection and surveillance of CRC. | Kim YC Fung Edouard Nice Ilka Priebe Damien Belobrajdic Aloke Phatak Leanne Purins Bruce Tabor Celine Pompeia Trevor Lockett Timothy E Adams Antony Burgess Leah Cosgrove | 2014 | World Journal of Gastroenterology2014，20，4： | 2 |
| 6 | Systematic review of outcomes for endoscopic sinus surgery and subsequent aspirin desensitization in aspirin-exacerbated respiratory disease显示文摘Objective:To review and evaluate outcomes of patients with aspirin-exacerbated respiratory disease(AERD)following endoscopic sinus surgery and subsequent aspirin desensitization.Methods:Electronic searches of OVID MEDLINE(1948 to September 10,2019),EMBASE(1980 to September 10,2019),and PubMed were performed on September 10,2019.A systematic review of the literature was performed using the 2009 PRISMA guidelines.Studies with both preoperative and postoperative data for patients with AERD who underwent sinus surgery and aspirin desensitization were considered appropriate for inclusion.Publications were written in English and included patients aged 18 years or older.Results:Six studies met inclusion criteria for this systematic review.The primary outcome measure was change in symptom profile measured by patient-reported quality of life scores.The results demonstrate statistically significant improvement in symptoms following endoscopic sinus surgery,with sustained improvement following aspirin desensitization.Revision surgery rates were significantly lower in patients maintained on aspirin therapy.Conclusion:This review suggests that surgery followed by aspirin desensitization results in improvement in both subjective and objective outcome measures.The adjunctive use of aspirin desensitization allows for long-term stability in symptom scores.Recurrence of polyps and worsening symptoms requiring revision surgery occurs when aspirin maintenance therapy is inter-rupted. | Lindsey Ryan Daniel Segarra Mark Tabor Arjun Parasher | 2020 | World Journal of Otorhinolaryngology-Head and Neck Surgery2020，6，4： | 2 |
| 7 | 丙型肝炎病毒的流行与结构——HCV所致肝细胞癌会议概述显示文摘本文介绍了1991年3月由日本和美国从事丙型肝炎病毒(HCV)研究的专家参加的丙型肝炎病毒所致肝细胞癌(HCC)会议的概况.这次会议主要探讨了HCV与HCC的相关性,HCV的基因组结构,HCV的株变异,测定HCV感染的方法及抗HCV的治疗方法等.会议旨在通过交流最新研究进展,以加快了解HCC的病因. | Tabor E 侯莉 张景云 | 1992 | 国外医学(流行病学.传染病学分册)1992，19，4： | 2 |
| 8 | herative equations in Banach spaces显示文摘 | Tabor J Zoldak M | 2004 | J Math Anal Appl2004，299，： | 1 |
| 9 | Surface forces and surface interactions显示文摘 | Tabor D | 1977 | Journal of Colloid and Interface Science1977，58，1： | 1 |
| 10 | A new catalytically active colloidal platinum nanocatalyst: the multi- armed nanostar single crystal显示文摘 | MAHMOUD M A TABOR C E EL-SAYED M A | 2008 | Journal of the American Chemi- cal Society2008，130，14： | 1 |
| 11 | Escherichia coli thiore- doxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7 显示文摘 | TABOR S HUBER H E RICHARDSON C C | 1987 | J Biol Chem1987，262，16： | 1 |
| 12 | Acid cleavable PEG-lipids for applications in a ternary gene delivery vector 显示文摘 | Wong J B Grosse S Tabor A B | 2008 | Mol Biosys2008，4，6： | 1 |
| 13 | Electromagnetic Propagation through materials Possessing both Faraday rotation and birefringence:experiments with Ytterbium Qrthoferrite显示文摘 | W J Tabor F S Chen | | 0，，07： | 1 |
| 14 | Narrowing the distance:Implementing a hybrid learning mod- el 显示文摘 | TABOR S W | 2007 | Quarterly Review of Distance Education2007，8，1： | 1 |
| 15 | Same-sample determination of ultratrace levels of polybromodiphenyle- thers, polybromodibenzo-p-dioxins/furans, and polych- lorodibenzo-p-dioxins/furans from combustion flue gas 显示文摘 | Wyrzykowska B Tabor D Gullett B K | 2009 | Analytical Chemistry2009，81，11： | 1 |
| 16 | Stability of Surjectivity显示文摘 | TABOR J | 2000 | J Approx Theory2000，105，1： | 1 |
| 17 | Randomized controlled trial of genelie amniocenlesis in 4606 low-risk women 显示文摘 | Tabor A Philip J Madsen M | 1986 | Lancet1986，8493，： | 1 |
| 18 | Junction growth in metallic friction: The role of combined stresses and surface contamination 显示文摘 | TABOR D | 1959 | Proc R Soc London Ser A1959，251，： | 1 |
| 19 | Comparative sensitivity of HBV NATs and HBsAg assays for detection of acute HBV infee- tion显示文摘 | Biswas R Tabor E Hsia CC | 2003 | Transfusion2003，43，6： | 1 |
| 20 | A new type cylindrical magnetic domain(bubble isomers)显示文摘 | TABOR W J BOBECK A H VELLA-COLEIRO G P | 1972 | Bell Syst Tech J1972，51，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员