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2篇 您的检索式:作者名="Gavin Tabor"
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1基于图像处理的个性化建模:从医学扫描到高精度计算模型的转换(英文)显示文摘目的对于生物力学领域的研究者来说,计算仿真技术已成为一种不可或缺的工具。对于这种工具的性能,至关重要的一点在于其有效模拟个性化问题方面的能力。本文将阐述能将三维数字图像(由CT、超声机或MRI扫描仪生成的)直接转换生成高精度计算模型的一种独特的非常有效的方法。方法采用的方法主要涉及:基于扫描的数据生成可输出到商业网格器中的表面模型——这种方法非常费时并且不是很精确,事实上对于复杂拓扑结构的影像数据这种方法很难处理:另外一种更加直接的方法是将几何模型的生成和网格划分一次性完成——这种方法先对感兴趣区域(三维图像分割)进行识别分割,然历直接生成基于一种由定义的边界分割的体素的体网格,这种方法被用来在整个体模型生成四面体和/或六面体单元,从而直接划分网格。结果采用一种基于图像的网格方法来处理问题是非常先进的,也是非常精确有效的。这种基于图像自动生成的网格,其有限元单元模型区域边界正好在等值面上因此其考虑了局部体效应从而能保证局部体素的精确度。结论对影像数据进行网格化是挑战也是机遇,这种与以往方法思想不一样的方法,在很多例子中,获得了更好的结果。这种能简易生成精确模型的方法,对于当前很多数值分析难以处理的问题诸如血液流体和病人个性化假体设计等提供了新的解决方案。XIA Ling Rajab Said Philippe Young Gavin Tabor Sam Coward HUANG Jean 2008医用生物力学2008,23,1:4
2On Modeling Bio-Scaffolds:Structural and Fluid Transport Characterization Based on 3-D Imaging Data显示文摘Bio-scaffolds which are most commonly open celled porous structures are increasingly used for tissue engineering and regenerative medicine. A number of studies have shown that the bulk properties of such irregular structures are poorly modeled using idealized unit cell approaches. The paper therefore uses novel image based meshing techniques to explore both fluid flow and bulk structural properties of a bone scaffold, as accurate modeling of bio-scaffolds with non-uniform cellular structures is very important for the development of optimal scaffolds for tissue engineering application. In this study, a porous hydroxyapatite/tricalcium phosphate (HA/TCP) bone scaffold has been scanned in a Micro-CT scanner, and converted into a volumetric mesh using image processing software developed by the authors. The resulting mesh was then exported to commercial FEA and CFD solvers for analysis. Initial FEA and CFD studies have shown promising results and have highlighted the importance of accurate modeling to understand how microstructures influence the mechanical property of the scaffold, and to analyze flow regimes through the sample. The work highlights the potential use of image based meshing for the ad hoc characterization of scaffolds as well as for assisting in the design of scaffolds with tailored strength, stiffness, and transport properties.NOTARBERARDINO Bruno BAKER Matthew TABOR Gavin TURNER Irene YANG Lincoln 2009Tsinghua Science and Technology2009,14,S1:1
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