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| 1 | Microfluidic actuators based on temperature-responsive hydrogels显示文摘The concept of using stimuli-responsive hydrogels to actuate fluids in microfluidic devices is particularly attractive,but limitations,in terms of spatial resolution,speed,reliability and integration,have hindered its development during the past two decades.By patterning and grafting poly(N-isopropylacrylamide)PNIPAM hydrogel films on plane substrates with a 2μm horizontal resolution and closing the system afterward,we have succeeded in unblocking bottlenecks that thermo-sensitive hydrogel technology has been challenged with until now.In this paper,we demonstrate,for the first time with this technology,devices with up to 7800 actuated micro-cages that sequester and release solutes,along with valves actuated individually with closing and opening switching times of 0.6±0.1 and 0.25±0.15 s,respectively.Two applications of this technology are illustrated in the domain of single cell handling and the nuclear acid amplification test(NAAT)for the Human Synaptojanin 1 gene,which is suspected to be involved in several neurodegenerative diseases such as Parkinson’s disease.The performance of the temperature-responsive hydrogels we demonstrate here suggests that in association with their moderate costs,hydrogels may represent an alternative to the actuation or handling techniques currently used in microfluidics,that are,pressure actuated polydimethylsiloxane(PDMS)valves and droplets. | Loïc D'Eramo Benjamin Chollet Marie Leman Ekkachai Martwong Mengxing Li Hubert Geisler Jules Dupire Margaux Kerdraon Clémence Vergne Fabrice Monti Yvette Tran Patrick Tabeling | 2018 | Microsystems & Nanoengineering2018，4，1： | 3 |
| 2 | Flow characteristics of liquid with pressure-dependent viscosities in microtubes显示文摘沿着在管子流动的轴的方向的压力坡度根据 Hagen-Poiseuille 方程保持不变,是明显的。然而,最近的实验显示压力的分发在高压力(1-30MPa ) 驾驶的微试管为液体流似乎不再线性。把方程基于 H-P 与滑动边界状况和布里奇曼粘性对静态的压力的关系,沿着轴的方向的压力的非线性的分发在这篇论文被分析。有考虑的压力依赖者粘性的效果的修订标准 Poiseuille 数字与试验性的结果同意很好。因此,压力上的粘性的依赖是在高驾驶的压力下面的统治因素之一,并且被液体的重要性质系数 α
代表。 | Zhanhua Silber-Li Haihang Cui Yuping Tan Patrick Tabeling | 2006 | Acta Mechanica Sinica2006，22，1： | 2 |
| 3 | Clinical features of children with Henoch-Schonlein purpura:risk factors associated with re-nal involvement显示文摘 | Tabel Y Inanc FC Dogan DG | 2012 | Iran J Kidney Dis2012，6，4： | 1 |
| 4 | Nanofluidics in the Debye layer at hydrophilic and hydrophobic surfaces显示文摘 | Bouzigues C I Tabeling P Bocquet L | 2008 | Phys Rev Letters2008，101，11： | 1 |
| 5 | Chaotic mixing in cross-channel micmmixers显示文摘 | TABELING P CHABERT M DODGE A | 2004 | Royal Society of London Transactions Series A2004，362，1818： | 1 |
| 6 | Interleukin 8 gene 2767 A/G polymorphism is associated with increased risk of nephritis in children with Henoch-Sch? nlein purpura显示文摘 | Tabel Y Mir S Berdeli A | | 0，，： | 1 |
| 7 | Sudden increase of the fractal dimension in a hydrodynamic system显示文摘 | | 1985 | Phys Rev1985，31，5： | 1 |
| 8 | Serum cystatin C pre- dicts acute kidney injury in preterm neonates with respira- tory distress syndrome 显示文摘 | Elmas A T Tabel Y Elmas O N | 2013 | Pediatr Nephrol2013，28，3： | 1 |
| 9 | Expression profile of the sphingusine kinase signalling system in the lung of patients with chronic obstructive pulmonary disease显示文摘 | Cordts F Pitson S Tabeling C | 2011 | Life Sci2011，89，2122： | 1 |
| 10 | History and epizootiology of Rabies in canada显示文摘 | Tabel H Corner A H Webster W A | 1974 | Can Vet J1974，15，： | 1 |
| 11 | Association of TLR2 gene Arg753Gln polymorphism with urinary tract infection in children显示文摘 | Tabel Y Berdeli A Mir S | 2007 | Int J Im- munogenet2007，34，6： | 1 |
| 12 | Cystatin C measurement and its practical use in patients with various renal disease显示文摘 | Tian S Kusano E Tabel K | 1997 | Clin Nephrol1997，48，： | 1 |
| 13 | diltiazem provides higher internal mammary artery flow than nitroglycerin during coronary artery bypass grafting 显示文摘 | Tabel Y Erdal C | 2004 | European Journal of Cardiothoracic Surgery2004，25，： | 1 |
| 14 | Helicobacter pylori infection inhibits healing of the wounded duodenal epithelium in vitro显示文摘 | Hoa NT Tarnawski A | 2003 | J Lab Clin Med2003，142，： | 1 |
| 15 | Genetic characterization of southwest German sweet chestnut by use of molecular markers显示文摘 | Schiffer M Maurer W D Tabel U | 2002 | Forstliche Versuchsanstalt Rheinland-Pfalz2002，49，2： | 1 |
| 16 | Regulatory T cells prevent control of experimental African trypanosomiasis显示文摘 | Wei G Tabel H | 2008 | J Immunol2008，180，4： | 1 |
| 17 | Clinical features ofchildren with Henoch-Schonlein purpura:risk factors assoc-iated with renal involvement显示文摘 | Tabel Y Inanc F C Dogan D G | | Iran J Kidney Dis0，6，4： | 1 |
| 18 | Ordered and disordered patterns in two-phase flows in microchannels 显示文摘 | DREYFUS R TABELING P WILLAIME H | 2003 | Phys RevLett2003，9014，14： | 1 |
| 19 | Possible interesting dietetic effects of lactulose as a feed additive in pig feed 显示文摘 | Kamphues J Tabeling R Stuke O | 2003 | Deutsche Tierarztliche Wochenschrift2003，110，9： | 1 |
| 20 | Milk as an interim storage medium for avulsed teeth显示文摘 | COURTS FJ MUELLER WA TABELING HJ | 1983 | Pediatr Dent1983，5，3： | 1 |
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