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| 1 | Medical and alternative therapies in urinary tract stone disease显示文摘Nephrolithiasis is a serious problem for both patients and the health system. Recurrence stands out as a significant problem in urinary system stone disease, the prevalence of which is increasing gradually. If recurrence is not prevented, patients may go through recurrent operations due to nephrolithiasis. While classical therapeutic options are available for all stone types, the number of randomized controlled studies and extensive meta-analyses focusing on their efficiency are inadequate. Various alternative therapeutic options to these medical therapies also stand out in recent years. The etiology of urolithiasis is multifactorial and not always related to nutritional factors. Nutrition therapy seems to be useful, either along with pharmacological therapy or as a monotherapy. General nutrition guidelines are useful in promoting public health and developing nutrition plans that reduce the risk or attenuate the effects of diseases affected by nutrition. Nutrition therapy involves the evaluation of a patient's nutritional state and intake, the diagnosis of nutrition risk factors, and the organization and application of a nutrition program. The main target is the reduction or prevention of calculus formation and growth via decreasing lithogenic risk factors and increasing lithogenic inhibitors in urine. This review focuses briefly on classical medical therapy, along with alternative options, related diets, and medical expulsive therapy. | Ercan Yuvanc Erdal Yilmaz Devrim Tuglu Ertan Batislam | 2015 | World Journal of Nephrology2015，4，5： | 3 |
| 2 | Effect of growth hormone on small intestinal homeostasis relation to cellular mediators IGF-I and IGFBP-3显示文摘AIM:To evaluate the effects of growth hormone(GH) on the histology of small intestines which might be related to the role of insulin like growth factor(IGF)-I, IGF-binding protein 3(IGFBP-3)and its receptors. METHODS:Twelve week-old adult male Wistar albino rats were divided into two groups.The study group(n =10),received recombinant human growth hormone (rGH)at a dose of 2 mg/kg per day subcutaneously for 14 d and the control group(n=10)received physiologic serum.Paraffin sections of jejunum were stained with periodic acid shift(PAS)and hematoxylin and eosin(HE) for light microscopy.They were also examined for IGF-I, IGFBP-3 and IGF-receptor immunoreactivities.Staining intensity was graded semi-quantitatively using the HS- CORE. RESULTS:Goblet cells and the cells in crypt epitheliawere significantly increased in the study group compared to that of the control group.We have demonstrated an increase of IGF-I and IGFBP-3 immunoreactivities in surface epithelium of the small intestine by GH application.IGF-I receptor immunoreactivities of crypt,villous columnar cells,enteroendocrine cells and muscularis mucosae were also more strongly positive in the study group compared to those of in the control group. CONCLUSION:These findings confirm the important trophic and protective role of GH in the homeostasis of the small intestine.The trophic effect is mediated by an increase in IGF-I synthesis in the small intestine, but the protective effect is not related to IGF-I. | Betul Ersoy Kemal Ozbilgin Erhun Kasirga Sevinc Inan Senol Coskun Ibrahim Tuglu | 2009 | World Journal of Gastroenterology2009，15，43： | 2 |
| 3 | Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder显示文摘 | TUGLU C KARA SH CALIYURT O | 2003 | Psychopharmacology(Berl)2003，170，4： | 1 |
| 4 | Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2acell line显示文摘 | Mete M Aydemir I Tuglu IM | 2015 | Biotech Histochem2015，90，3： | 1 |
| 5 | A comparison of the neu- roablative effects of conventional and pulsed radiofrequency techniques 显示文摘 | Vatansever D Tekin I Tuglu I | 2008 | Clin J Pain2008，24，8： | 1 |
| 6 | Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder显示文摘 | Tuglu C Kara S H Caliyurt O | 2003 | Psychopharmacology2003，170，4： | 1 |
| 7 | Increased ser um tumor necrosis factor-alpha levels and treatment response in major depressive disorder显示文摘 | Tuglu C Kara SH Caliyurt O | 2003 | Psychopharmacology(Berl)2003，170，4： | 1 |
| 8 | Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder显示文摘 | Tuglu C Kara SH Caliyurt O | 2003 | Psychopharmacology (Berl)2003，170，4： | 1 |
| 9 | C-reactive protein in early detection of bacteriemia and bacteriuria after extracorporeal shock wave lithotripsy显示文摘 | Yilmaz E Batislam E Tuglu D | 2003 | European Urology2003，，03： | 1 |
| 10 | Protective effect of leukotriene receptor antagonist montelukast on smoking-induced lung injury in Wistar rats 显示文摘 | Yuksel H Ozbilgin K Coskun S Tuglu I | 2003 | Acta Med Okayama2003，57，1： | 1 |
| 11 | Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder显示文摘 | Tuglu C Kara SH Caliyurt O | 2003 | Psychopharmacology(Berl)2003，170，4： | 1 |
| 12 | C-reactive protein inearly detection of bacteriemia and bacteriuria after extra-corporeal shock wave lithotripsy显示文摘 | Yilmaz E Batislam E Tuglu D | 2003 | Eur Urol2003，43，3： | 1 |
| 13 | Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder显示文摘 | Kara SH Caliyurt O | 2003 | Psychopharmacology (Berl)2003，170，： | 1 |
| 14 | Increased serum tumor necrosis factor- alpha levels and treatment response in major depressive disorder显示文摘 | Tuglu C Kara SH Caliyurt O | 2003 | Psychopharmacology (Berl)2003，170，4： | 1 |
| 15 | THE COMPARISON AND EFFICACY OF 3 DIFFERENT α1-ADRENERGIC BLOCKERS FOR DISTAL URETERAL STONES显示文摘 | ERDAL YILMAZ ERTAN BATISLAM MEHMED MURAD BASAR DEVRIM TUGLU MEHMET FERHAT HALIL BASAR | 2005 | The Journal of Urology2005，，6： | 1 |
| 16 | Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder显示文摘 | Tuglu C Kara SH Caliyurt O | 2003 | Psychopharmacology(Berl)2003，170，4： | 1 |
| 17 | Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder 显示文摘 | Tuglu C Kara SH Caliyurt O | 2003 | Psychopharmacology (Bed)2003，170，4： | 1 |
| 18 | C-reactive protein in early detection of bacteriuriaafter extracoreal shock wave lithotripsy显示文摘 | Yilmaz E Batilam E Tuglu D | 2003 | Europena Urology2003，43，： | 1 |
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