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| 1 | Therapeutic effectiveness of a single exercise session combined with WalkAide functional electrical stimulation in post-stroke patients:a crossover design study显示文摘A growing body of evidence has suggested that the imbalance of epigenetic markers and oxidative stress appears to be involved in the pathophysiology and progression of stroke.Thus,strategies that modulate these biomarkers might be considered targets for neuroprotection and novel therapeutic opportunities for these patients.Physical exercise has been reported to induce changes in these epigenetic markers and improve clinical outcomes in different populations.However,little is reported on this in post-stroke patients.The purpose of this study was to investigate the effect of a single exercise session with WalkAide functional electrical stimulation(FES)on cognitive performance,clinical functional parameters,oxidative stress and epigenetic modulation in post-stroke individuals.In this crossover design study,12 post-stroke individuals aged 54–72 years of either sexes were included and subjected to a single session of exercise(45 minutes)without WalkAide functional electrical stimulation(EXE alone group),followed by another single session of exercise(45 minutes)with WalkAide functional electrical stimulation(EXE+FES group).The clinical functional outcome measures,cognitive performance and blood collections for biomarker measurements were assessed pre-and post-intervention.After intervention,higher Berg Balance Scale scores were obtained in the EXE+FES group than in the EXE alone group.There was no significant difference in the Timed Up and Go test results post-intervention between EXE alone and EXE+FES groups.After intervention,a better cognitive performance was found in both groups compared with before the intervention.After intervention,the Timed Up and Go test scores were higher in the EXE+FES group than in the EXE alone group.In addition,the intervention induced lower levels of lipid peroxidation.After intervention,carbonyl level was lower,superoxide dismutase activity and superoxide dismutase/catalase activity ratio were higher in the EXE+FES group,compared with the EXE group alone.In each group,both histone deacetylase(HDAC2)and histone acetyltransferase activities were increased after intervention compared with before the intervention.These findings suggest that a single exercise session with WalkAide FES is more effective on balance ability and cognitive performance compared with conventional exercise alone in post-stroke patients.This is likely to be related to the regulation of oxidative stress markers.The present study was approved by the Research Ethics Committee of the Methodist University Center-IPA(approval No.2.423.376)on December 7,2017 and registered in the Brazilian Registry of Clinical Trials—ReBEC(RBR-9phj2q)on February 11,2019. | Viviane Rostirola Elsner Lucieli Trevizol Isadora de Leon Marcos da Silva ThaynáWeiss Milena Braga Daniela Pochmann Amanda Stolzenberg Blembeel Caroline Dani Elenice Boggio | 2021 | Neural Regeneration Research2021，16，5： | 3 |
| 2 | Short - channel effects and drain - induced barrier lowering in nanometerscale GaAs MESFET's 显示文摘 | James A Adams Thayne I G Wilkinson C D W | 1993 | IEEE Trans Electron Devices1993，40，6： | 1 |
| 3 | Novel high uniformity highly reproduci- ble non-selective wet digital gate recess etch process for InP HEMTs 显示文摘 | CAO X THAYNE | 2003 | Microelectronic Eng2003，67，： | 1 |
| 4 | Novel high uniformity highly repro ducible non-selective wet digital gate recess etch process for InP HEMTs 显示文摘 | CAO X THAYNE I | 2003 | Microelectronic Eng2003，6768，： | 1 |
| 5 | The role of rhizobacteria in rice plants: Growth and mitigation of toxicity显示文摘Allelopathic compounds reduce the growth and productivity of upland rice plants, especially in consecutive plantations. The rhizobacteria Pseudomonas fluorescens BRM-32111 and Burkholderia pyrrocinia BRM-32113 have been recorded as growth promoters in rice. This study was developed to understand the effect of the application of rhizobacteria on upland rice plants in consecutive plantations. Experiments were conducted in a completely randomized design with four replications of four treatments: rice seed inoculated with P. fluorescens BRM-32111, rice seed inoculated with B. pyrrocinia BRM-32113(both sown on soil with rice residue), non-inoculated plants sown on soil with rice residue(control with residue(WR)), and non-inoculated plants on soil with no residue(NR). Roots and seedling growth were adversely affected by allelopathic compounds in control WR plants. Plants inoculated with rhizobacteria P. fluorescens BRM-32111 or B. pyrrocinia BRM-32113 induced an increase of 88% in biomass, 3% in the leaf area, 40% in length, 67% in root biomass, 21% in chlorophyll a, 53% in chlorophyll(a+b), 50% in rate of carbon assimilation(A), 227% in A/rubisco carboxylation efficiency(C_i) and 63% in water use efficiency(WUE) compared to control WR plants. These results indicate that rhizobacteria P. fluorescens BRM-32111 and B. pyrrocinia BRM-32113 increase the tolerance of rice plants to stress from allelochemicals. There are possible practical agricultural applications of these results for mitigating the effects of environmental allelochemistry on upland rice. | Marcela C F Rêgo Aline F Cardoso Thayná da C Ferreira Marta C C de Filippi Telma F V Batista Rafael G Viana Gisele B da Silva | 2018 | Journal of Integrative Agriculture2018，17，12： | 1 |
| 6 | Age, dose of FSH and other factors affecting superovulation in holstein cow显示文摘 | Lerner S P Thayne W V Baker R D | 1986 | Journal of Animal Science1986，63，： | 1 |
| 7 | Microfluidic diagnostic technologies forglobal public health 显示文摘 | Paul Yager Thayne Edwards Elain Fu | 2006 | Nature2006，442，： | 1 |
| 8 | The amygda]a and related structures in the pathophysiol- ogy of autism显示文摘 | Thayne L | 2002 | Pharmacology Biochemistry and Behavior2002，71，3： | 1 |
| 9 | Julian Dates and Introduced Temporal Error in Remote Sensing Vegetation Phenology Studies显示文摘 | Thayn J B Price K P | 2008 | International Journal of Remote Sensing2008，29，20： | 1 |
| 10 | Na + , K + ATPase alpha -subunit isoforrn distribution and abundance in guinea- pig longitudinal muscle/myenteric plexus after exposure to morphine 显示文摘 | Biser PS Thayne KA Fleming WW | 2002 | Brain Res2002，931，2： | 1 |
| 11 | Microfluidic di-agnostic technologies forglobal public health 显示文摘 | Paul Yager Thayne Edwards Elain Fu | 2006 | Nature2006，442，： | 1 |
| 12 | A microfabricated thermal field-flow fractionation system显示文摘 | Thayne L Edwards Bruce K Gale A Bruno Frazier | 2002 | Anal Chem2002，74，： | 1 |
| 13 | Age, dose of FSH and other factors affecting superovulation in holstein cow显示文摘 | Lemer S P Thayne W V Baker R D | 1986 | Joumal of animal science1986，63，： | 1 |
| 14 | Microfluidic Diagnostic Technologies for Global Public Heath显示文摘 | Paul Yager Thayne Edwards Elain Fu | 2006 | Nature2006，442，7101： | 1 |
| 15 | Gallium oxide (Ga 2 O 3 ) on gallium arsenide—A low defect, high-K system for future devices显示文摘 | G.W. Paterson J.A. Wilson D. Moran R. Hill A.R. Long I. Thayne M. Passlack R. Droopad | 2006 | Materials Science & Engineering B2006，，3： | 1 |
| 16 | Age, does of FSH and other factors affecting superovulation in Holstein cows 显示文摘 | Lender S P Thayne W V Bake R D | 1986 | J Anim Sci1986，，63： | 1 |
| 17 | Graph-based technologies for intelligence analysis显示文摘 | Thayne Coffman Seth Greenblatt Sherry Marcus | 2004 | Communications of the ACM2004，47，3： | 1 |
| 18 | Evaluation of microwave thermotherapy with histopathology, magnetic resonance imaging and temperature mapping 显示文摘 | CHRISTIAN H MAGNUS B THAYNE L | 2004 | J Urol2004，171，2： | 1 |
| 19 | Near-infrared imaging survey of faint companions around young dwarfs in the Pleiades cluster显示文摘We conducted a near-infrared imaging survey of 11 young dwarfs in the Pleiades cluster using the Subaru Telescope and the near-infrared coronagraph imager. We found ten faint point sources,with magnitudes as faint as 20 mag in the K-band,with around seven dwarfs.Comparison with the Spitzer archive images revealed that a pair of the faint sources around V 1171 Tau is very red in infrared wavelengths,which indicates very low-mass young stellar objects.However,the results of our follow-up proper motion measurements implied that the central star and the faint sources do not share common proper motions,suggesting that they are not physically associated. | Yoichi Itoh Yumiko Oasa Hitoshi Funayama Masahiko Hayashi Misato Fukagawa Toshio Hashiguchi Thayne Currie | 2011 | Research in Astronomy and Astrophysics2011，11，3： | 0 |
| 20 | 太阳系的婴儿照显示文摘我们的太阳系在诞生之初是何模样?各个行星出现干何时?要返回到过去为早期太阳系拍照显然是不可能的,但我们可以退而求其次:找到年龄在100万年至500万年之间的类日恒星,拍摄它们的新生的行星系统,我们认为,这个年龄段正是巨行星的形成时间。 | Thayne M.Currie Chfol A.Grady 吴蕴豪(译) | 2012 | 中国国家天文2012，，8： | 0 |
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