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1Improved two-cuff technique for orthotopic liver transplantation in rat显示文摘BACKGROUND: The first orthotopic liver transplantatio in rat (ROLT) was reported by Lee in 1973. Kamada inno vatively applied cuff technique to ROLT in 1979. However the operative procedures were highly demanding and th operative mortality was relatively high. The purpose of thi study was to improve the model of ROLT, simplify opera tive procedures, and enhance the successful rate of opera tion. METHODS: Orthotopic liver transplantation was per formed in 160 Wistar rats by improved two-cuff technique The portal vein between donor and recipient was anasto mosed with the cuff technique. The same method was use to anastomose the infrahepatic vena cava. The suprahepati vena cava and the hepatic artery were anastomosed by m crovascular suturing and the bile duct was anastomosed en to end by a Teflon catheter. RESULTS: The average time for donor operation, graf preparation and anhepatic phase was 31 minutes, 14 mi nutes and 13 minutes, respectively. The anastomosis tim for the suprahepatic vena cava, portal vein, infrahepatic ve na cava, hepatic artery and bile duct was 7 minutes, 2 mi nutes, 2 minutes, 8 minutes and 1 minute, respectively The main causes for operative mortality were pneumotho rax, anesthesia, air embolism and massive bleeding, an the successful rate of operation was 92.5%. The causes fo death after operation were stoma bleeding, infection, b liary obstruction and graft failure. CONCLUSION: The improved two-cuff technique can re duce operative mortality, enhance survival rate, and serv as an ideal method for the establishment of animal model o ROLT.Yong Peng, Jian-Ping Gong, Lu-Nan Yan, Shou-Bo Li and Xu-Hong Li Chongqing, China Department of Hepatobiliary Surgery, Second Affilia- ted Hospital, Chongqing Medical University, Chongqing 400010, China Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041 , China 2004Hepatobiliary & Pancreatic Diseases International2004,3,1:17
2Abnormal expression of hepatoma- derived γ-glutamyltransferase subtyping and its early alteration for carcinogenesis of hepatocytes显示文摘BACKGROUND: Although the hepatoma-specific band of gamma-glutamyltransferase ( GGT ) is a highly sensitive marker in diagnosis of hepatocellular carcinoma, the kine- tic expression and the early alterations of GGT in the deve- lopment of hepatoma remain unclear. In this study, we in- vestigated the expression and the alterations of GGT multi- ple molecular forms in hepatotumorigenesis. METHODS: The expression of GGT in a chemically in- duced hepatocarcinogenesis model was examined by giving 0. 05% of 2-fluoenylacetamide in diet for 12 weeks. The ex- pression levels of total RNA and GGT, and the changes of liver pathology, GGT multiple molecular forms and sugar- chain heterogeneity were investigated at the different stages of rat hepatoma development. RESULTS: Pathological examination and biochemical ana- lysis found that liver GGT was over-expressed and secreted into blood during canceration. Serum total GGT and liver GGT specific activities (IU/g) including soluble and mem- brane-combined GGT were significantly higher (P <0.05) in experimental groups than those in control group, respec- tively. A highly positive correlation was found between to- tal GGT activities and total RNA levels (r =0.90, P <0.05) of the liver. Both were higher six weeks later than before. Con A-non-reactive-GGT was increased consistantly dur- ing the development of rat hepatoma. GGT multiple mo- lecular forms in the liver and sera of experimental rats showed that fetal liver-type GGT bands were associated with the development of hepatoma. CONCLUSIONS: Fetal liver-type GGT in sera and the liver of rats is closely related to hepatotumorigenesis. It can be used as a sensitive enzymatic marker for the early diagnosis of liver cancer.Deng-Fu Yao, Zhi-Zhen Dong, Deng-Bing Yao, Xin-Hua Wu, Wei Wu, Li-Wei Qiu, Hong-Mei Wang and Xian-Yong Meng Nantong, China Research Center of Clinical Molecular Biology, Affilia- ted Hospital of Nantong University, Nantong 226001 , China Insti- tute of Neuroscicnces, Nantong University, Nantong 226001 , China 2004Hepatobiliary & Pancreatic Diseases International2004,3,4:17
3A Microarray Analysis of Angiogenesis Modulation Effect of Xuefu Zhuyu Decoction (血府逐瘀汤) on Endothelial Cells显示文摘学习 Xuefu Zhuyu 煎的 angiogenesis 调整机制的目的() 在 endothelial 房间线 ECV304 上。宋军 陈文元 吴立娅 郑良朴 林薇 高冬 Ted J.Kaptchuk 陈可冀 2012Chinese Journal of Integrative Medicine2012,18,7:16
4The Effect of Xuefu Zhuyu Decoction(血府逐瘀汤) on in vitro Endothelial Progenitor Cell Tube Formation显示文摘观察 Xuefu Zhuyu 煎的效果的目的(endothelial 上的琛€搴滈€愮榾姹 ? 包含浆液(XFZYD-CS ) 在 vitro 的祖先房间(EPC ) 试管形成。从老鼠骨头髓的方法 Mononuclear 房间在一台 Ficoll 密度坡度离心机被准备。EPC 被微分附件方法分开,并且在 EPC 试管形成上为 XFZYD-CS 的效果与转换显微镜观察了。在一天以后的结果,暴露于包含 5% , 10% 和 15% 的浆液的 EPC XFZYD-CS 形成了典型试管或容器网络。试管形成时间是在控制组前的二天,在浆液组的大多数试管的尺寸比在控制组小。结论 XFZYD-CS 能导致 EPC angiogenesis 并且赶快试管形成,特别在毛状的容器。学习在 ischemic 疾病的治疗为 Xuefu Zhuyu 煎的似有道理提供试验性的证据。关键词 Xuefu Zhuyu 煎 - endothelial 祖先房间 - 试管形成由中国(号码 30772877 ) 的国家自然科学基础支持了;中国医药科学的中国学院的基本研究资金(没有。ZZ2006039 ) ;综合的药基础(号码 3000-905010805 )高冬 吴立娅 焦雨欢 陈文元 陈岩 Ted J.Kaptchuk 逯波 宋军 陈可冀 2010Chinese Journal of Integrative Medicine2010,16,1:16
5男男性行为人群同性恋身份自我认同与艾滋病危险因素的相关性显示文摘[目的]探索男男性接触者(MSM)对自己同性恋身份的认同及其与艾滋病相关危险因素的关系。[方法]使用统一设计的调查问卷,对利用'滚雪球'、'网络动员'等途径招募的151名MSM采用匿名面对面询问方式调查其自我认同、性行为、性伴网络、吸毒史和健康相关行为。[结果]消极自我认同的比例为56.29%(85/151)。文化程度与自我认同有关联性(χ2=8.022,P<0.05)。自认性取向为同性恋的积极自我认同比例高于自认性取向为双性恋和异性恋者(χ2=5.108,P<0.05)。不同自我认同和与男性首次性行为年龄、与异性结婚可能性、人类免疫缺陷病毒(HIV)抗体检测率、过去6个月有异性性伴/固定男性伴/多次男性伴等因素的关联有统计学意义(P值均<0.05),其中积极自我认同的MSM与男性首次性行为更多发生在20岁以前、与异性结婚可能性小、更易接受HIV检测服务、拥有固定男性伴比例高、拥有异性性伴和多次男性伴的比例小。[结论]MSM人群消极自我认同的比例较高,其无保护性交和多性伴较广泛地存在,主动求医进行HIV抗体检测率较低,感染HIV危险性和传播桥梁作用也更大。应广泛开展社会反歧视宣传,促进MSM积极自我认同,增进艾滋病预防服务利用,有效降低艾滋病传播的风险。石国政 殷方兰 张永 宁镇 钟培松 Sarah Jane Steele Ted Myers 2012环境与职业医学2012,29,5:16
6Effect of EphB4/EphrinB2 Reverse Signal on Angiogenesis Induced by Xuefu Zhuyu Capsule(血府逐瘀胶囊) Containing Serum in Human Microvascular Endothelial Cell 1显示文摘Objective: To evaluate the effect of Xuefu Zhuyu Capsule(血府逐瘀胶囊)-containing serum(XFZY-CS) on Eph B4/ephrin B2 and its reverse signal in human microvascular endothelial cell-1(HMEC-1). Methods: XFZY-CS and the blank control serum were collected. HMEC-1 cells were randomly assigned to 6 groups including the concentration 1.25%, 2.5%, and 5% XFZY-CS groups and their blank serum control ones. The angiogenesis effect of XFZY-CS was tested with an in vitro tube formation assay and the best condition of pro-angiogenesis was determined. The effect of XFZY-CS on Eph B4/ephrin B2 and the reverse signal were determined by Western blot and real-time quantitative polymerase chain reaction, respectively; we also confirmed the results through activating and inhibiting the reverse signal by Eph B4/fc and pyrophosphatase/phosphodiesterase2(PP2). Results: XFZY-CS promoted angiogenesis at the concentration of 2.5% corresponding serum after being cultured for 48 h, while inhibited angiogenesis at the concentration of 5% after culturing for 48 and 72 h. Under the 2.5% serum concentration, XFZY up-regulated the expression of Eph B4-m RNA at 12 h(P<0.05), and down-regulates its expression at 24 h(P<0.01). Protein expression of Eph B4 was apparently up-regulated at 12 h and down-regulated at 24 h. The phosphorylation of ephrin B2 increased at 9 h(P<0.05). In addition, 2.5% XFZY-CS played a similar role as the reverse signaling activator Eph B4/Fc ranging from 0.5 to 5 μg/m L(P>0.05). XFZY-CS also reduced the inhibitive effect of PP2 in limited periods. Conclusion: Eph B4/ephrin B2 was the upstream signal in the process of angiogenesis and its reverse signaling was responsible for XFZY's effect on promoting angiogenesis.张静思 王一铮 胡雅琼 林凡 高冬 宋军 Ted J.Kaptchuk 陈可冀 2016Chinese Journal of Integrative Medicine2016,22,8:13
7汉语第三人称回指语形式眼动阅读实验显示文摘回指是篇章连贯的主要手段之一,受多种因素影响。前人文献较少关注回指语形式对回指的影响,而这正是汉语篇章的特色之一。本文运用眼动实验的范式考察汉语母语者阅读理解第三人称回指语形式(第三人称代词或零形式)的差异,包括认知加工时间的长短以及是否影响回指对象的判定,并对比相关语言学研究,旨在揭示汉语母语者理解篇章回指的机制。实验发现:1)汉语母语者阅读话题接续的篇章时,零形式快于代词;而阅读话题转换的篇章时,代词快于零形式。可见母语者对篇章连贯性和回指语形式之间的对应关系非常敏感,篇章连贯性和回指语形式之间有相互作用。2)不管是零形式还是代词,母语者都倾向认为其回指主语,即回指语形式不影响回指对象的判定,但读者会根据篇章的展开理解并修正对回指的判断,证明篇章回指的理解是一个动态的调整过程。李榕 Pim MAK Ted SANDERS 2016中国语文2016,,1:10
8农民生产投资的影响因素分析——基于监督分组的主成分回归分析显示文摘本文提出基于监督分组的主成分回归分析法(Supervised Classification-based Principal Component Regress Analysis)用以分析存在互相关的各因素对目标因素的贡献。先将自变量按照理论及实际经验进行分类,然后各类分别进行主成分分析,每类得出的主成分与因变量做回归分析,从而得出自变量与因变量的关系。本文采用1993—2007年陕西省的时间序列数据实证分析了影响农民生产投资的诸多因素,包括农民家庭纯收入、农民生活消费支出、家庭经营费用支出、农户耕地及灌溉面积、生产资料及农产品价格、公共投资等。分析显示当前农民投资的主要来源是家庭收入,农产品价格、公共投资、灌溉面积都对农户投资有显著影响。尹文静 王礼力 Ted McConnel 2011农业技术经济2011,,2:8
9Effects of somatostatin analogues on human sphincter of Oddi pressure显示文摘BACKGROUND: Somatostatin, a neuropeptide and hor- mone , exists in the biliary tract of several species. The effects of somatostatin and its analogues on the sphincter of Oddi motility have been controversial. The aim of this study was to observe the action of stilamin and sandostatin on the sphincter of Oddi via choledochofiberscope manometry. METHODS: Twenty patients who had had'T' duct after cholecystectomy and choledochotomy were divided into 2 groups randomly: stilamin and sandostatin. They were subjected to manometry via a choledochofiberscope through the’T’ duct tract. The following data recorded in- cluded duodenal pressure (DP), sphincter of Oddi basal pressure (SOBP), sphincter of Oddi contractive amplitude (SOCA), frequency of the sphincter of Oddi (SOF), dura- tion of the sphincter of Oddi, and the common bile duct pressure (CBDP). RESULTS: After intravenous administration of stilamin at a dose of 250 μg/h, the mean SOCA increased from 89.18 (26.50) to 128.57(54.21) mmHg (P <0.05). After the ad- ministration of stilamin at a dose of 500 μg/h the mean SO- CA declined to 92.18(42.81) mmHg (P<0.05), and mean SOBP declined from 17.63(13.36) to 8.16(4.01) mmHg (P<0.05). Although SOF had declined from 9.25(2.45) to 7.46(1.52) n/min, it was not significantly influenced. After intravenous administration of sandostatin at a dose of 100 μg, the mean CBDP increased obviously. CONCLUSIONS: Intravenous administration of stilamin at a dose of 250 μg/h stimulates the motility of the sphincter of Oddi whereas the injection of stilamin at a dose of 500 μg/h inhibits its motility. Intravenous injection of sandosta- tin of 100 μg has no effect on the sphincter of Oddi.Shuo-Dong Wu, Zhen-Hai Zhang, Jing Kong, Yan-Jun Li, Jun-Zhe Jin, Wei Wang, Dong-Yan Li and Min-Fei Wang Shenyang, China No.2 Department of General Surgery, Second Affilia- ted Hospital, China Medical University, Shenyang 110004, China 2005Hepatobiliary & Pancreatic Diseases International2005,4,2:8
10某区男男性行为人群性伴网络特征与高危行为分析显示文摘[目的]了解男男性行为(MSM)人群性伴网络特征及该人群中高危性行为的发生情况,探讨性病(STDs)、人类免疫缺陷病毒(HIV)在该人群中传播及向普通人群传播的模式,为开展性病、艾滋病预防控制提供依据。[方法]通过艾滋病自愿咨询检测门诊、同性恋人群活动场所、同性恋QQ群内动员、'滚雪球'等途径寻找MSM人群,招募151人,采用面对面匿名问卷调查方式收集信息。[结果]151名被调查者中最近6个月有30人(19.9%)与异性发生过性行为,高危性行为的发生率为53.3%;与同性性活动情况,其中91人(60.3%)有同性固定性伴,76人(50.3%)与非固定同性性伴的人发生过多次男男性行为(简称有多次男性伴),77人(51.0%)发生过偶遇性行为(简称有偶遇男性伴),10人(6.6%)从事商业性行为。而在与固定性伴、多次男性伴、偶遇男性伴、商业性行为中高危性行为的发生率依次是69.2%、57.9%、50.6%、70.0%。与固定男性伴高危性行为的发生率高于与偶遇男性伴高危性行为的发生率(P=0.014)。最近6个月有2种及以上性伴类型占58.9%。30名已感染HIV者中有多次男性伴及偶遇男性伴类型的比例分别为53.3%和63.3%;有过多次男性伴、偶遇男性伴性行为者中发生高危性行为的比例分别为50.0%和63.2%。感染HIV者与固定男性伴发生高危性行为的率低于未感染HIV者(P=0.029)。[结论]MSM人群性伴网络复杂多样,高危性行为发生率高。不仅使HIV在该人群中容易传播,且该人群已成为向普通人群传播HIV的'桥梁'人群。张永 石国政 殷方兰 钟平 Sarah Jane Steele Ted Myers 2012环境与职业医学2012,29,5:8
11Blood glucose changes surrounding initiation of tumor-necrosis factor inhibitors and conventional disease-modifying anti-rheumatic drugs in veterans with rheumatoid arthritis显示文摘AIM To determine the scope of acute hypoglycemic effects for certain anti-rheumatic medications in a large retrospective observational study. METHODS Patients enrolled in the Veterans Affairs Rheumatoid Arthritis (VARA) registry were selected who, during follow-up, initiated treatment with tumor necrosis factor inhibitors (TNFi's, including etanercept, adalimumab, infliximab, golimumab, or certolizumab), prednisone, or conventional disease-modifying anti-rheumatic drugs(DMARDs), and for whom proximate random blood glucose (RBG) measurements were available within a window 2-wk prior to, and 6 mo following, medication initiation. Similar data were obtained for patients with proximate values available for glycosylated hemoglobin A1C values within a window 2 mo preceding, and 12 mo following, medication initiation. RBG and A1C measurements were compared before and after initiation events using paired t-tests, and multivariate regression analysis was performed including established comorbidities and demographics.RESULTS Two thousands one hundred and eleven patients contributed at least one proximate measurement surrounding the initiation of any examined medication. A significant decrease in RBG was noted surrounding 653 individual hydroxychloroquine-initiation events(-3.68 mg/dL, P = 0.04), while an increase was noted for RBG surrounding 665 prednisone-initiation events(+5.85 mg/d L, P < 0.01). A statistically significant decrease in A1C was noted for sulfasalazine initiation, as measured by 49 individual initiation events(-0.70%, P < 0.01). Multivariate regression analyses, using methotrexate as the referent, suggest sulfasalazine (β =-0.58, P = 0.01) and hydroxychloroquine(β =-5.78, P = 0.01) use as predictors of lower post-medicationinitiation RBG and A1C values, respectively. Analysis by drug class suggested prednisone (or glucocorticoids) as predictive of higher medication-initiation event RBG among all start events as compared to DMARDs, while this analysis did not show any drug class-level effect for TNFi. A diagnosis of congestive heart failure(β = 4.69, P = 0.03) was predictive for higher post-initiation RBG values among all medication-initiation events.CONCLUSION No statistically significant hypoglycemic effects surrounding TNFi initiation were observed in this large cohort. Sulfasalazine and hydroxychloroquine may have epidemiologically significant acute hypoglycemic effects.Patrick R Wood Evan Manning Joshua F Baker Bryant England Lisa Davis Grant W Cannon Ted R Mikuls Liron Caplan 2018World Journal of Diabetes2018,9,2:8
12男男性行为者社会网络及性行为特征的研究显示文摘[目的]了解男男性行为者(men who have sex with men,MSM)人群社会网络及性行为特征,为MSM人群干预提供参考。[方法]采用统一设计的问卷进行面对面调查,并用描述性、卡方检验等方法进行分析。[结果]151名被调查对象拥有128个社交网络;网络大小为2~6个节点,其中≥4个节点的占32.93%;网络密度为0.40~1.00,中位数为1.00;社会网络成员中,男性占85.86%,≤30岁者占73.73%,大学及以上文化程度者占49.93%,被调查对象与社交对象年龄、文化程度的构成差异无统计学意义。297名社交对象中,属于朋友或同学者占61.62%,同事占15.15%,性伴占12.12%,亲属占11.11%;56.23%是MSM;24.58%曾与被调查对象发生性行为,其中76.71%在过去6个月发生过性关系。被调查对象首次与男性发生性行为的年龄为13~40岁,平均(22.73±5.14)岁;在过去6个月中,男性伴个数为1~101个,中位数为2个;60.93%有2个以上男性伴,与固定男性伴、多次男性伴、偶遇男性伴、商业男性伴、异性性伴不安全性行为发生率分别为51.65%、46.05%、36.84%、75.00%和53.33%。[结论]MSM人群多性伴、无保护性行为普遍,社会网络是艾滋病危险行为扩散的重要影响因素,应根据各地区网络社交的特点,开展针对性艾滋病防治。殷方兰 石国政 任金马 庄琴 Sarah Jane Steele Ted Myers 2012环境与职业医学2012,29,3:8
13男男性行为人群双性性行为的发生及影响因素显示文摘[目的]调查男男性行为者(menwhohavesexwithmen,MSM)中双性性行为的发生情况及艾滋病相关的高危行为发生情况,分析MSM发生异性性行为的原因及影响因素,为减少艾滋病由高危人群向一般人群扩散,更好地开展艾滋病高危行为干预工作提供思路。[方法]采用横断面调查研究的方法,于2010年6_12月按年龄段在上海市浦东新区进行分层抽样,对符合入选标准的研究对象进行一对一的问卷调查,收集一般人口学信息、工作生活状况、社交网络与性行为情况、艾滋病相关知识和态度等资料并进行相关的统计描述与分析。[结果]共收集有效问卷158份;66.5%(105/158)的MSM来自上海以外省市;17.7%(28/158)的MSM表示自己是双性恋,27.8%(44/158)的MSM表示过去5年和女性有过性活动,差异有统计学意义(x2=4.60,P〈0.05);和女性有过性活动的MSM人群中最近一次性行为中安全套使用率为80.O%(12/15),最近6个月每次安全套使用率为53-3%(8/15);非条件logistic回归分析结果表明,影响MSM人群与女性发生性行为的因素有婚姻状况(OR=10.53,95%CI:3.07~36.13)和性取向(OR=82.86,95%CI:16.35-419.86)。[结论]MSM人群中的双性恋是将人类免疫缺陷病毒从MSM人群向一般人群扩散的主要人群,一部分男男同性恋由于婚姻原因和女性发生性行为,进一步增加了人类免疫缺陷病毒向一般人群扩散的力度,应从家庭和社会环境的角度加以防治。李朋 张枭 毛军 孙乔 肖绍坦 黄星 宁镇 Sarah Jane Steele Ted Myers 2012环境与职业医学2012,29,6:7
14上海市男男商业性服务人群健康和行为状况调查显示文摘[目的]了解上海市男男商业性服务人群(money boy,MB)的基本特征、艾滋病(AIDS)相关行为、健康和感染情况,探索适合该人群的AIDS宣传教育和行为干预措施。[方法]通过艾滋病自愿咨询检测(VCT)门诊、网络及同志关爱小组动员共招募124名男男性行为者(MSM),分为MB组和非MB组,采用匿名问卷调查和血清学检测方法获取两组的AIDS相关健康、行为以及感染状况。[结果]MB组平均年龄26.0岁,初/高中及以下文化水平者占76.9%,非沪户籍者占92.3%;非MB组平均年龄29.3岁,大学及以上文化水平者占71.4%,非沪户籍者占61.2%。MB组性取向以双性恋为主,占80.8%,异性性伴侣较多;非MB组中73.5%为同性恋,62.3%的人仅和男性发生性行为。MB组首次与男性发生性行为的平均年龄为20.8岁,不安全性行为发生率可达31.2%~68.8%,疾病风险意识较非MB组低。MB组HIV和梅毒的感染率均为4.5%;非MB组中HIV和梅毒感染率分别为5.6%和6.7%,两组间差异无统计学意义(P〉0.05)。[结论]MB人群具有更多的艾滋病传播危险因素,有关部门应重视加强与非政府组织合作,深入地开展宣传教育和行为干预工作,提高该群体对AIDS风险和安全性行为的认识。蔡晓峰 杨美霞 刘阳 宁镇 Sarah Jane Steele Ted Myers 2012环境与职业医学2012,29,4:7
15Analysis of the current rib support practices and techniques in U.S. coal mines显示文摘Design of rib support systems in U.S. coal mines is based primarily on local practices and experience. A better understanding of current rib support practices in U.S. coal mines is crucial for developing a sound engineering rib support design tool. The objective of this paper is to analyze the current practices of rib control in U.S. coal mines. Twenty underground coal mines were studied representing various coal basins,coal seams,geology,loading conditions,and rib control strategies. The key findings are:(1) any rib design guideline or tool should take into account external rib support as well as internal bolting;(2) rib bolts on their own cannot contain rib spall,especially in soft ribs subjected to significant load—external rib control devices such as mesh are required in such cases to contain rib sloughing;(3) the majority of the studied mines follow the overburden depth and entry height thresholds recommended by the Program Information Bulletin 11-29 issued by the Mine Safety and Health Administration;(4) potential rib instability occurred when certain geological features prevailed—these include draw slate and/or bone coal near the rib/roof line,claystone partings,and soft coal bench overlain by rock strata;(5) 47% of the studied rib spall was classified as blocky—this could indicate a high potential of rib hazards; and(6) rib injury rates of the studied mines for the last three years emphasize the need for more rib control management for mines operating at overburden depths between 152.4 m and 304.8 m.Mohamed Khaled M. Murphy Michael M. Lawson Heather E. Klemetti Ted 2016International Journal of Mining Science and Technology2016,26,1:6
16Cancer treatment and survivorship statistics, 2012显示文摘Rebecca Siegel Carol DeSantis Katherine Virgo Kevin Stein Angela Mariotto Tenbroeck Smith Dexter Cooper Ted Gansler Catherine Lerro Stacey Fedewa Chunchieh Lin Corinne Leach Rachel Spillers Cannady Hyunsoon Cho Steve Scoppa Mark Hachey Rebecca Kirch Ahmed 2012CA: A Cancer Journal for Clinicians2012,,4:6
17农村公共投资对农民生产投资影响的区域差异——基于卡尔曼滤波的时序列分析显示文摘本文选取东部地区的山东省、中部地区的安徽省、西部地区的陕西省作为研究对象,采用带有时变参数的状态空间模型分析1990~2007年全国各地区农村公共投资和农民生产投资之间的关系。研究发现,农村公共投资对农民生产投资的影响不仅因为不同地区市场因素、农户特征等因素的不同而对农民生产投资表现出不同的影响程度,而且这种影响关系随着时间变化产生波动。这一关系的跳跃性变化往往与国家重要政策的出台和经济水平的迅速发展密切相关。尹文静 Ted McConnel 2012中国农村观察2012,,3:5
18A history of high-power laser research and development in the United Kingdom显示文摘The first demonstration of laser action in ruby was made in 1960 by T.H.Maiman of Hughes Research Laboratories,USA.Many laboratories worldwide began the search for lasers using different materials,operating at different wavelengths.In the UK,academia,industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of applications.This historical review looks at the contribution the UK has made to the advancement of the technology,the development of systems and components and their exploitation over the last 60 years.Colin N.Danson Malcolm White John R.M.Barr Thomas Bett Peter Blyth David Bowley Ceri Brenner Robert J.Collins Neal Croxford A.E.Bucker Dangor Laurence Devereux Peter E.Dyer Anthony Dymoke-Bradshaw Christopher B.Edwards Paul Ewart Allister I.Ferguson John M.Girkin Denis R.Hall David C.Hanna Wayne Harris David I.Hillier Christopher J.Hooker Simon M.Hooker Nicholas Hopps Janet Hull David Hunt Dino A.Jaroszynski Mark Kempenaars Helmut Kessler Sir Peter L.Knight Steve Knight Adrian Knowles Ciaran L.S.Lewis Ken S.Lipton Abby Littlechild John Littlechild Peter Maggs Graeme P.A.Malcolm OBE Stuart P.D.Mangles William Martin Paul McKenna Richard O.Moore Clive Morrison Zulfikar Najmudin David Neely Geoff H.C.New Michael J.Norman Ted Paine Anthony W.Parker Rory R.Penman Geoff J.Pert Chris Pietraszewski Andrew Randewich Nadeem H.Rizvi Nigel Seddon MBE Zheng-Ming Sheng David Slater Roland A.Smith Christopher Spindloe Roy Taylor Gary Thomas John W.G.Tisch Justin S.Wark Colin Webb S.Mark Wiggins Dave Willford Trevor Winstone 2021High Power Laser Science and Engineering2021,9,2:5
19A case study of multi-seam coal mine entry stability analysis with strength reduction method显示文摘In this paper,the advantage of using numerical models with the strength reduction method(SRM) to evaluate entry stability in complex multiple-seam conditions is demonstrated.A coal mine under variable topography from the Central Appalachian region is used as a case study.At this mine,unexpected roof conditions were encountered during development below previously mined panels.Stress mapping and observation of ground conditions were used to quantify the success of entry support systems in three room-and-pillar panels.Numerical model analyses were initially conducted to estimate the stresses induced by the multiple-seam mining at the locations of the affected entries.The SRM was used to quantify the stability factor of the supported roof of the entries at selected locations.The SRM-calculated stability factors were compared with observations made during the site visits,and the results demonstrate that the SRM adequately identifies the unexpected roof conditions in this complex case.It is concluded that the SRM can be used to effectively evaluate the likely success of roof supports and the stability condition of entries in coal mines.Tulu Ihsan Berk Esterhuizen Gabriel S. Klemetti Ted Murphy Michael M. Sumner James Sloan Michael 2016International Journal of Mining Science and Technology2016,26,2:5
20OPTIMUM CHANNEL GEOMETRY AND MINIMUM ENERGY DISSIPATION RATE显示文摘The theory of minimum rate of energy dissipation in conjunction with Yang’s sediment transport equation and Manning’s equation for water discharge is used to derive the optimum open channel geometry. The optimum channel geometry thus derived is consistent with those based on the tractive force approach and is identical to those hosed on the least wetted perimeter for a given cross-sectional area with the maximum conveyance. laboratory and field data are used to support the theoretical analyses.Chih Ted Yang and Charles C. S. Song International and Special Projects Coordinator, U. S. Bureau of Reclamation, Denyer, Colorado 80225, U. S. A. Professor, St. Anthony Falls Hydraulic Laboratory, University of Minnesota, MinneaPOlis, Minnesota 55414, U. S. A. 1990International Journal of Sediment Research1990,5,1:5
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