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| 1 | Antioxidant potential,tannin and polyphenol contents of seed and pericarp of three Coffea species显示文摘Objective:To investigate the antioxidant activity,total phenolic and total tannin content of the pericarp and the seed of Coffea benghalensis(C.benghalensis) and Coffea liberica compared to Coffea arabica(C.arabica).Methods:The antioxidant potential,total tannin and polyphenol contents of the immature and mature seed and pericarp of C.benghalensis and Coffea liberica were quantified and compared to C.arabica.Enhanced chemiluminescence(ECL).2,2-diphenyl-1-picrylhydruzyl(DPPH).oxygen radical absorbance capacity,Folin-Ciocaltcau method and total tannin content assays were used.Results:Trolox equivalent(TE/g plant material) values obtained by ECL and DPPH methods showed loose correlation(r^2=0.587)while those measured by oxygen radical absorbance capacity assay were higher without correlation in each plant.A closer correlation was detected between the ECL method and the percentage antioxidant activity of the DPPH technique(r^2=0.610 7) in each species,however the immature pericarp of C.benghalensis showed much higher DPPH scavenging potential than was seen in the ECL assay.The immature pericarp of C.benghalensis expressed the highest tannin and polyphenol content,and a high polyphenol level was also detected in the immature seed of C.arabica.The immature pericarp of Bengal and Liberian coffees showed the largest amount of phenolic contents.Conclusions:The obtained data highlight the potential role of C.benghalensis as a new source of natural antioxidants and polyphenols compared to C.arabica. | va Brigitta Patay Nikolett Sali Tams Kszegi Rita Csepregi Viktória Lilla Blaz Tibor Sebastian Németh Tibor Németh Nóra Papp | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，4： | 3 |
| 2 | Frequency and prognostic role of mucosal healing in patients with Crohn's disease and ulcerative colitis after one-year of biological therapy显示文摘AIM:To assess the endoscopic activity before and after a one-year period of biological therapy and to evaluate the frequency of relapses and need for retreatment after stopping the biologicals in patients with Crohn’s disease(CD)and ulcerative colitis(UC).METHODS:The data from 41 patients with CD and 22 patients with UC were assessed.Twenty-four CD patients received infliximab,and 17 received adalimumab.The endoscopic severity of CD was quantified with the simplified endoscopic activity score for Crohn’s disease in CD and with the Mayo endoscopic subscore in UC.RESULTS:Mucosal healing was achieved in 23 CD and7 UC patients.Biological therapy had to be restarted in78%of patients achieving complete mucosal healing with CD and in 100%of patients with UC.Neither clinical remission nor mucosal healing was associated with the time to restarting the biological therapy in either CD or UC.CONCLUSION:Mucosal healing did not predict sustained clinical remission in patients in whom the biological therapies had been stopped. | Klaudia Farkas Péter László Lakatos Mónika Szcs va Pallagi-Kunstár Anita Bálint Ferenc Nagy Zoltán Szepes Noémi Vass Lajos S Kiss Tibor Wittmann Tamás Molnár | 2014 | World Journal of Gastroenterology2014，20，11： | 2 |
| 3 | Elevated insulin-like growth factor 1 receptor, hepatocyte growth factor receptor and telomerase protein expression in mild ulcerative colitis显示文摘 | Ferenc Sipos Orsolya Galamb László Herszényi Béla Molnár Norbert Solymosi Tamás Zágoni Lajos Berczi Zsolt Tulassay | 2008 | Scandinavian Journal of Gastroenterology2008，，3： | 2 |
| 4 | Gastroesophageal reflux disease after diagnostic endoscopy in the clinical setting显示文摘AIM: To investigate the outcome of patients with symptoms of gastroesophageal reflux disease (GERD) referred for endoscopy at 2 and 6 mo post endoscopy. METHODS: Consecutive patients referred for upper endoscopy for assessment of GERD symptoms at two large metropolitan hospitals were invited to participate in a 6-mo non-interventional (observational) study.The two institutions are situated in geographically and socially disparate areas. Data collection was by selfcompletion of questionnaires including the patient assessment of upper gastrointestinal disorders symptoms severity and from hospital records. Endoscopic finding using the Los-Angeles classification, symptom severity and it's clinically relevant improvement as change of at least 25%, therapy and socio-demographic factors were assessed. RESULTS: Baseline data were available for 266 patients and 2-mo and 6-mo follow-up data for 128 and 108 patients respectively. At baseline, 128 patients had erosive and 138 non-erosive reflux disease. Allmost all patient had proton pump inhibitor (PPI) therapy in the past. Overall, patients with non-erosive GERD at the index endoscopy had significantly more severe symptoms as compared to patients with erosive or even complicated GERD while there was no difference with regard to medication. After 2 and 6 mo there was a small, but statistically significant improvement in symptom severity (7.02 ± 5.5 vs 5.9 ± 5.4 and 5.5 ± 5.4 respectively); however, the majority of patients continued to have symptoms (i.e. , after 6 mo 81% with GERD symptoms). Advantaged socioeconomic status as well as being unemployed was associated with greater improvement. CONCLUSION: The majority of GORD patients receive PPI therapy before being referred for endoscopy even though many have symptoms that do not sufficiently respond to PPI therapy. | Nora B Zschau Jane M Andrews Richard H Holloway Mark N Schoeman Kylie Lange William CE Tam Gerald J Holtmann | 2013 | World Journal of Gastroenterology2013，19，16： | 2 |
| 5 | Short-term postural reflexes in diabetic patients with autonomic dysfunction 显示文摘 | ZHANG Y CRITCHLEY L A TAM Y H TOMLINSON B | 2004 | Diabetologia2004，47，： | 1 |
| 6 | Mathematical modeling of the role of mitochondrial fusion and fission in mitochondrial DNA maintenance显示文摘 | Tam ZY Gruber J Halliwell B | 2013 | PLo S One2013，8，10： | 1 |
| 7 | Nitrogen use efficiency characteristics of Andigena and diploid potato selections 显示文摘 | Zebarth B J Tam T R Jong H de | 2008 | American Journal of Potato Research2008，85，： | 1 |
| 8 | Ribavirin polarizes human T cell responses towards a type 1 cytokine profile显示文摘 | Tam RC Pai B Bard J | 1999 | J Hepatol1999，30，3： | 1 |
| 9 | Synthesis and anti-HIV activity of isonucleosides显示文摘 | HURYN D M SLUBOSKI B C TAM S Y | 1992 | J Med Chem1992，35，13： | 1 |
| 10 | VEGF is necessary for exercise-induced adult hippocampal neurogenesis显示文摘 | FABEL K FABEL K TAM B | 2003 | Eur J Neurosci2003，18，10： | 1 |
| 11 | Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas显示文摘 | Loda M Cukor B Tam SW | 1997 | Nat Med1997，3，2： | 1 |
| 12 | Respiratory complications from nasalpacking;systematic review显示文摘 | Rotenberg B Tam S | 2010 | J Otolaryngol Head Neck Surg2010，39，5： | 1 |
| 13 | Homoclinic orbits for the coupled Schrfidinger - Boussinesq equation and coupled Higgs equation 显示文摘 | HU X B GUO B L TAM H | 2003 | J Phys Soc Jpn2003，71，1： | 1 |
| 14 | Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs显示文摘 | Lai EC Tam B Rubin GM | 2005 | Genes Dev2005，19，9： | 1 |
| 15 | HER- 2/neu and breast cancer 显示文摘 | Kaptain S Tam LK Chen B | 2001 | Diagn Mol Patho12001，10，： | 1 |
| 16 | Determination of plasma cholesterol sulfate by LC-APCI-MS/MS in the context of pediatric autism显示文摘 | FONG B M TAM S LEUNG K S | 2013 | Talanta2013，116，： | 1 |
| 17 | Urinary monocyte chemoattractant protein-1 (MCP-1) and conneetive tis- sue growth lactor (CCN2) as prognostic markers for progression of diabetic nephropathy显示文摘 | Tam F W Riser B L Meeran K | 2009 | Cytokine2009，47，： | 1 |
| 18 | Formation of stable homodi- met via the C-terminal alpha-helical domain of coronavirus nonstructural protein 9 is critical for its function in viral replication 显示文摘 | Chen B Fang S Tam J P | 2009 | Virology2009，383，2： | 1 |
| 19 | High efficiency and small roll-off electrophosphorescence from a new iridium complex with well-matched energy levels显示文摘 | Gao Z Q Mi B X Tam H L | | 0，，04： | 1 |
| 20 | Green,yellow,and or- ange defect emission from ZnO nanostructures: Influence of exci tation wavelength显示文摘 | DJUIRIS1C A B LEUNG Y H TAM K H | 2006 | Appl Phys Lett2006，，： | 1 |
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