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| 1 | Colorectal cancer surveillance in inflammatory bowel disease:Practice guidelines and recent developments显示文摘Patients with long-standing inflammatory bowel disease(IBD)involving at least 1/3 of the colon are at increased risk for colorectal cancer(CRC).Advancements in CRC screening and surveillance and improved treatment of IBD has reduced CRC incidence in patients with ulcerative colitis and Crohn’s colitis.Most cases of CRC are thought to arise from dysplasia,and recent evidence suggests that the majority of dysplastic lesions in patients with IBD are visible,in part thanks to advancements in high definition colonoscopy and chromoendoscopy.Recent practice guidelines have supported the use of chromoendoscopy with targeted biopsies of visible lesions rather than traditional random biopsies.Endoscopists are encouraged to endoscopically resect visible dysplasia and only recommend surgery when a complete resection is not possible.New technologies such as virtual chromoendoscopy are emerging as potential tools in CRC screening.Patients with IBD at increased risk for developing CRC should undergo surveillance colonoscopy using new approaches and techniques. | William T Clarke Joseph D Feuerstein | 2019 | World Journal of Gastroenterology2019，25，30： | 23 |
| 2 | Diagnosis of gastrointestinal bleeding: A practical guide for clinicians显示文摘Gastrointestinal bleeding is a common problem encountered in the emergency department and in the primary care setting. Acute or overt gastrointestinal bleeding is visible in the form of hematemesis, melena or hematochezia. Chronic or occult gastrointestinal bleeding is notapparent to the patient and usually presents as positive fecal occult blood or iron deficiency anemia. Obscure gastrointestinal bleeding is recurrent bleeding when the source remains unidentified after upper endoscopy and colonoscopic evaluation and is usually from the small intestine. Accurate clinical diagnosis is crucial and guides definitive investigations and interventions. This review summarizes the overall diagnostic approach to gastrointestinal bleeding and provides a practical guide for clinicians. | Bong Sik Matthew Kim Bob T Li Alexander Engel Jaswinder S Samra Stephen Clarke Ian D Norton Angela E Li | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，4： | 13 |
| 3 | World Review of Laparoscopic Liver Resection—2,804 Patients显示文摘 | Kevin Tri Nguyen T Clark Gamblin David A. Geller | 2009 | Annals of Surgery2009，，5： | 8 |
| 4 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009，7，4： | 3 |
| 5 | Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8^+ T cells during pregnancy显示文摘Listeria monocytogenes (Lm ) 为发展中的胎儿在怀孕和疾病的后果期间是有为全身的母亲的感染的唯一的倾向的一个细胞内部的细菌。给与出生前的 Lm 感染联系的高死亡,为在怀孕的极其脆弱的经期期间扩充保护的免疫的策略着急地被需要。此处,保护由在对随后的剧毒的 Lm 出生前的感染的怀孕被评估以前,管理的稀释 Lm 交谈了。因为显著地更多的细菌从母亲的纸巾被恢复,我们证明对在非怀孕的老鼠的第二等的 Lm 感染的保护严厉地在 allogeneic 怀孕期间被节制,尽管有病原体特定的 CD8 + T 房间的数字、功能的保藏。更重要地,因为各在怀孕和天真的怀孕控制以前与稀释 Lm 接种的老鼠在怀孕期间在 Lm 感染以后从单个 concepti 显示出近完全的胎儿的再吞和病原体恢复, preconceptual priming 不在 utero 侵略或胎儿的消耗量免于。显著地,对有在 allogeneic 怀孕的 preconceptual priming 的出生前的 Lm 感染的保护的缺乏在 syngeneic 怀孕期间被恢复。因此,母亲胎儿的抗原不和在出生前的 Lm 感染以后对胎儿的复杂并发症支配 preconceptual 种痘的低效率,尽管有病原体特定的 CD8 + T 房间的数字、功能的保藏。 | Dayna R Clark Vandana Chaturvedi Jeremy M Kinder Tony T Jiang Lijun Xin James M Ertelt Sing Sing Way | 2014 | Cellular & Molecular Immunology2014，11，6： | 3 |
| 6 | Passive Immunization of Channel Catfish (Ictalurus punctatus) against the Ciliated Protozoan Parasite Ichthyophthirius multifiliis by Use of Murine Monoclonal Antibodies显示文摘 | Lin Tian-Long Clark T G Dickerson H W | 1996 | Infection and Immunity1996，64，10： | 2 |
| 7 | Immunisation of Channel Catfish, Ictalurus punctatus, with Ichthyophthirius multifiliis Immobilisation antigens elicits serotype-specific protection 显示文摘 | Wang Xu-Ting Clark T G Jane Noe | 2002 | Fish Shellfish Immunol2002，13，： | 2 |
| 8 | The gene for an abundant parasite coat protein predicts tandemly repetitive mental binding domains 显示文摘 | Clark T G Lin Tian-Long Jackwood D A | 1999 | Gene1999，229，： | 2 |
| 9 | Stem cells,cancer,and cancer stem cells显示文摘 | Reya T Morrison SJ Clarke MF | | 0，，6859： | 2 |
| 10 | Immune response of fish to ciliates显示文摘 | Dickerson H W Clark T G | 1996 | Annu Rev of Fish Dis1996，6，： | 2 |
| 11 | Thermal degradation of Nicalon SiC fiber 显示文摘 | CLARK T J ARONS R M STAMATOFF J B | 1985 | Ceram Eng Sci Proc1985，6，78： | 2 |
| 12 | Isolation of an unidentified agent from the respiratory tract of chickens显示文摘 | Bankowski R A Corstert R E Clark C T | 1960 | Science1960，132，： | 2 |
| 13 | Prediction of the occurrence of slope instability phenomena through GIS-based hazard zonation显示文摘 | CLARK V W RENGERS M T TERLIEN J K | 1997 | Geology Rundsch1997，86，： | 2 |
| 14 | Tumor necrosis factor-alpha expression in ischemic neurons 显示文摘 | Liu T Clark RK McDonnell PC | 1994 | Stroke1994，25，： | 2 |
| 15 | The CN2 induction algorithm显示文摘 | Clark P Niblett T | 1989 | Machine Learning1989，3，4： | 2 |
| 16 | Tumor neurosis factor-alpha expression in ischemic neurons显示文摘 | Lin T Clark RK McDonnell PC | 1994 | Stroke1994，25，7： | 1 |
| 17 | Alumina-supported molybdenum phosphide hydroprocessing catalysts 显示文摘 | Clark P A Oyama S T | 2003 | Journal of Catalysis2003，218，： | 1 |
| 18 | Catalytic cracking of rosin显示文摘 | CLARK I T HARRIS E E | 1952 | Am Chem Soc1952，，74： | 1 |
| 19 | N-methyl-D-aspartate and brain-derived neurotrophic factor induce distinct profiles of extracellular signal-regulated kinase,mitogen-and stress-activated kinase,and ribosomal s6 kinase phosphorylation in cortical neurons显示文摘 | Rakhit S Clark CJ O'shaughnessy T C | 2005 | Mol Pharmacol2005，67，4： | 1 |
| 20 | J Mater Chem 显示文摘 | Tavener S J Barlow S T | 1995 | (5): 827-301995，，5： | 1 |
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