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| 1 | 心衰所致肠道血流减少或促进恶病质发生显示文摘慢性心力衰竭是一种多系统疾病,其最终阶段为心源性恶病质,而恶病质是一种严重的并发症,提示预后不良。越来越多证据表明胃肠道在慢性心力衰竭营养失调和恶病质中扮演着重要的病理生理角色,研究表明慢性心衰患者肠道形态和功能均发生显著变化,而肠道血流受限或许可以解释上述变化。 | Sandek A Swidsinski A Schroedl W | 2014 | 中华结直肠疾病电子杂志2014，3，5： | 47 |
| 2 | Spatial organization of bacterial flora in normal and inflamed intestine: A fluorescence in situ hybridization study in mice显示文摘AIM: To studythe role of intestinal flora in inflammatory bowel disease (IBD).METHODS: The spatial organization of intestinal flora was investigated in normal mice and in two models of murine colitis using fluorescence in situ hybridization.RESULTS: The murine small intestine was nearly bacteriafree. The normal colonic flora was organized in three distinct compartments (crypt, interlaced, and fecal), each with different bacterial compositions. Crypt bacteria were present in the cecum and proximal colon. The fecal compartment was composed of homogeneously mixed bacterial groups that directly contacted the colonic wall in the cecum but were separated from the proximal colonic wall by a dense interlaced layer. Beginning in the middle colon, a mucus gap of growing thickness physically separated all intestinal bacteria from contact with the epithelium. Colonic inflammation was accompanied with a depletion of bacteria within the fecal compartment, a reduced surface area in which feces had direct contact with the colonic wall, increased thickness and spread of the mucus gap, and massive increases of bacterial concentrations in the crypt and interlaced compartments. Adhesive and infiltrative bacteria were observed in inflamed colon only, with dominant Bacteroides species.CONCLUSION: The proximal and distal colons are functionally different organs with respect to the intestinal flora, representing a bioreactor and a Segregation device.The highly organized structure of the colonic flora, its specific arrangement in different colonic segments, and its specialized response to inflammatory stimuli indicate that the intestinal flora is an innate part of host immunity that is under complex control. | Alexander Swidsinski Vera Loening-Baucke Herbert Lochs Laura P.Hale | 2005 | World Journal of Gastroenterology2005，11，8： | 27 |
| 3 | Mucosal flora in inflammatory bowel disease显示文摘 | Alexander Swidsinski Axel Ladhoff Annelie Pernthaler Sonja Swidsinski Vera Loening-Baucke Marianne Ortner Jutta Weber Uwe Hoffmann Stefan Schreiber Manfred Dietel Herbert Lochs | 2002 | Gastroenterology2002，，1： | 2 |
| 4 | The role of bacteria in gallstone pathogenesis显示文摘 | Swidsinski A Lee SP | 2001 | Front Biosci2001，6，1： | 1 |
| 5 | Molecular genetic evidence of bactetial colonization of cholesterol gallastones 显示文摘 | Swidsinski A Ludwig W Pahlig H | 1995 | Gastroenterology1995，108，6： | 1 |
| 6 | The role of bacteriain gallstone pathogenesis显示文摘 | Swidsinski A Lee SP | 2001 | Front Biosci2001，6，： | 1 |
| 7 | Mucosal fla in inflmmatory bowel disease显示文摘 | SWIDSINSKI A LADHO PERNTHALER A | 2002 | Gastro- enterology2002，122，： | 1 |
| 8 | Gardnerella biofilm involves females and males and is transmitted sexually 显示文摘 | Swidsinski A Doerffel Y Loening-Baucke V | 2010 | Gynecol Obstet Invest2010，70，4： | 1 |
| 9 | Response of Gardnerella vaginalis biofilm to 5 days of moxifloxacin treatment 显示文摘 | Swidsinski A Dorffel Y Loening-Baucke V | 2011 | FEMS Immunol Med Microbiol2011，61，1： | 1 |
| 10 | An adherent Gardnerella vaginalis biofilm persists on the vaginal epithelium after standard therapy with oral metronidazole显示文摘 | Swidsinski A Mendling W Loening-Baucke V | | 0，，01： | 1 |
| 11 | Mucosal flora in inflammatory bowel disease显示文摘 | SWIDSINSKI A LADHOFF A PERNTHALER A | | 0，，01： | 1 |
| 12 | Mucosal flora in inflammatory bowel disease 显示文摘 | Swidsinski A Ladhoff A Pernthaler A | 2002 | Gastroenterology2002，122，1： | 1 |
| 13 | An adherent gardnereUa vaginaris biofllm persists on the vaginal epithelium after standard therapy with oral metronidazoh显示文摘 | Swidsinski A Mend ling W Loening Bancke V | 2008 | Am J Obstet Gynecol2008，198，： | 1 |
| 14 | Mueosal flora in inflammatory bowel disease显示文摘 | SWIDSINSKI A LADHOFF A PEMTHALER A | 2002 | Gastroenterology2002，122，： | 1 |
| 15 | An adherent Gardnerella vaginalis biofilm persists on the vaginal epithelium after standard therapy with oral metronidazole显示文摘 | Swidsinski A Mendling W Loening-Baucke V | 2008 | Am J Obstet Gynecol2008，198，97： | 1 |
| 16 | Mucosal flora in Crohn's disease and ulcerative colitis-an overview显示文摘 | Swidsinski A Loening-Baucke V Herber A | | 0，，6： | 1 |
| 17 | Active Crohn's disease and ulcerative colitis can be specifically diagnosed and monitored based on the biostructure of the fecal flora显示文摘 | Swidsinski A Loening-Baucke V Vaneechoutte M | 2008 | Inflamm Bowel Dis2008，14，2： | 1 |
| 18 | Mueosal fla in inflmma- tory bowel disease 显示文摘 | Swidsinski A Ladho Pernthaler A | 2002 | Gastroenterology2002，122，： | 1 |
| 19 | Mucosal flora in inflammatory bowel disease显示文摘 | Swidsinski A Ladhoff A Pimthaler A | 2002 | Gastroenterology2002，122，1： | 1 |
| 20 | Molecular genetic evidence of bacterial colonization of cholesterol gallstones显示文摘 | Swidsinski A Ludwig W Pahlig H | 1995 | Gastroenterology1995，108，3： | 1 |
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