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| 1 | Risk of complications and urinary incontinence following cytoreductive prostatectomy: a multi-institutional study显示文摘当时,新兴的证据建议了 cytoreductive 前列腺切除术(CRP ) 允许优异 oncologic 控制与照顾雄激素剥夺标准的电流相比治疗独自一个。然而,在变形前列腺癌症(mPCa ) 的 cytoreduction 的安全和利益没被证明。因此,我们评估了在最新与 mPCa 诊断的人跟随 CRP 的复杂并发症的发生。在四个第三级的外科的中心从 2006 ~ 2014 经历了 CRP 的 68 个病人的一个总数与为临床上局部性的前列腺癌症(PCa ) 经历了激进的前列腺切除术的 598 个人相比。尿不能自制被定义为任何垫的使用。CRP 有更长起作用的时间(200 min 对 140 min, P < 0.0001 ) 并且更高估计的血损失(250 ml 对 125 ml, P < 0.0001 ) 与控制组相比。然而,外套(8.82% 对 5.85%) 和主要复杂并发症率(4.41% 对 2.17%) 在二个组之间是可比较的。重要地,尿不能自制率在在外科以后 1 年在 CRP 组是显著地更高的(57.4% 对 90.8% , P < 0.0001 ) 。Univariate 逻辑分析证明估计的血损失在 unadjusted 模型两个都是 perioperative 复杂并发症的唯一的独立预言者(或:1.18;95% CI:1.02-1.37;P = 0.025 ) 并且外科调整类型的模型(或:1.17;95% CI:1.01-1.36;P = 0.034 ) 。在结论, CRP 比激进的前列腺切除术更挑战性、与尿不能自制的尤其是更高的发生联系。不过, CRP 是为选择谁的 PCa 病人的一个技术上可行、安全的手术与节点积极或多骨的转移在场当由富有经验的外科医生表现了时。未来的、多机构的临床的试用当前是在进行之中的验证这个概念。 | Dae Keun Kim Jaspreet Singh Parihar Young Suk Kwon Sinae Kim Brian Shinder Nara Lee Nicholas Farber Thomas Ahlering Douglas Skarecky Bertram Yuh Nora Ruel Wun-lae Kim Koon Ho Rha Isaac Yi Kim | 2018 | Asian Journal of Andrology2018,20,1: | 5 |
| 2 | Achievements and prospects of grass pea(Lathyrus sativus L.) improvement for sustainable food production显示文摘Grass pea offers an attractive choice for sustainable food production, owing to its intrinsic properties including limited water requirement and drought tolerance. However, low productivity and the presence of a neurotoxin(ODAP) have posed major obstacles to its genetic improvement. Also, biotechnological investments remain limited and the genome is complex and not well understood. Strategies that allow identification of genotypes with reduced ODAP content, coupling of low ODAP content with enhanced yield, and effective seed detoxification methods merit immediate attention. Breeder-friendly genomic tools are being increasingly made available to improve the efficiency of breeding protocols. To this end, the application of next-generation sequencing has provided a means of leveraging the repertoire of genomic resources for this somewhat neglected crop. In this review, we describe progress achieved in Lathyrus genetic improvement. We also explore potential opportunities in Lathyrus research and identify urgent research needs. | Girish Prasad Dixit Ashok Kumar Parihar Abhishek Bohra Narendra Pratap Singh | 2016 | The Crop Journal2016,4,5: | 3 |
| 3 | Next-Generation Intelligent MXene-Based Electrochemical Aptasensors for Point-of-Care Cancer Diagnostics显示文摘Delayed diagnosis of cancer using conventional diagnostic modalities needs to be addressed to reduce the mortality rate of cancer.Recently,2 D nanomaterial-enabled advanced biosensors have shown potential towards the early diagnosis of cancer.The high surface area,surface functional groups availability,and excellent electrical conductivity of MXene make it the 2 D material of choice for the fabrication of advanced electrochemical biosensors for disease diagnostics.MXene-enabled electrochemical aptasensors have shown great promise for the detection of cancer biomarkers with a femtomolar limit of detection.Additionally,the stability,ease of synthesis,good reproducibility,and high specificity offered by MXene-enabled aptasensors hold promise to be the mainstream diagnostic approach.In this review,the design and fabrication of MXene-based electrochemical aptasensors for the detection of cancer biomarkers have been discussed.Besides,various synthetic processes and useful properties of MXenes which can be tuned and optimized easily and efficiently to fabricate sensitive biosensors have been elucidated.Further,futuristic sensing applications along with challenges will be deliberated herein. | Arpana Parihar Ayushi Singhal Neeraj Kumar Raju Khan MohdAkram Khan Avanish KSrivastava | 2022 | Nano-Micro Letters2022,14,6: | 2 |
| 4 | Interleukin-2 enhances the natural cell response to Herceptin-coated Her2/neu-positive breast cancer cells显示文摘 | Carson WE Parihar R Lindemann MJ | 2001 | Eur J Immunol2001,31,10: | 1 |
| 5 | A chimeric multi-human epidermal growth factor receptor-2 B cell epitope peptide vaecine mediates superior antitumor responses显示文摘 | Dakappagari N K Pyles J Parihar R | 2003 | J Immunol2003,170,8: | 1 |
| 6 | Silicide/Si1-xGex Schottky barrier long-wavelength infrareddetectors显示文摘 | XIAO X STURM J C PARIHAR S R | 1992 | Electron Device Meeting Technical Digest1992,,1316: | 1 |
| 7 | Efficient SpuriousRejection and Null Steering Using Slot Antennas 显示文摘 | Parihar M S Basu A Koul S K | 2011 | IEEE Antennas and Wireless Propagation Letters2011,10,1: | 1 |
| 8 | Oxidative stress and anti-ox- idative mobilization in burn injury显示文摘 | Parihar A Parihar M S Milner S | 2008 | Burns2008,34,1: | 1 |
| 9 | Response of superoxide dismutase, glmathione peroxidase and reduced glutathione antioxidant defenses in gills of the freshwater catfish ( Heteropneustes fossilis ) to short-term elevated temperature 显示文摘 | Parihar M S Tarangini J Taruna H | 1997 | Journal of Thermal Biology1997,22,3: | 1 |
| 10 | Changes in free nucleotides,nucleosides and bases during thermal processing of goat and sheep meats显示文摘 | Arya S S Parihar D B | 1979 | Die Nahrung1979,23,: | 1 |
| 11 | Human papillomavirus E6 and E7 oncoproteins as risk factors for tumorigenesis 显示文摘 | Ganguly N Parihar SP | 2009 | J Biosci2009,34,1: | 1 |
| 12 | Charaeterization of a Thyristor Controlled Reactor 显示文摘 | Parihar P Karady G G | 1997 | Electric Power Systems Research1997,41,: | 1 |
| 13 | Experimental excitotoxicity provokes oxidetive damage in mice brain and attenuation by extract of Asparagus racemosus显示文摘 | Parihar MS Hemnani T | 2004 | J Neural Transm2004,111,1: | 1 |
| 14 | Gallic acid based steroidal phenstatin analogues for selective targeting of breast cancer cells through inhibiting tubulin polymerization显示文摘 | Swati Parihar Atul Gupta Amit K | 2012 | Sterodis2012,77,89: | 1 |
| 15 | Efficient SpuriousRejection and Null Steering Using Slot Antennas 显示文摘 | Parihar M S Basu A Koul S K | 2011 | IEEE Antennas and Wireless Propagation Letters2011,10,3: | 1 |
| 16 | Oxidative stress and anti - oxidative mobilization in burn injury 显示文摘 | Parihar A Parihar MS Milner S | 2008 | Bums2008,34,1: | 1 |
| 17 | Response of superoxide dismutase, glutathione peroxidase and reduced glutathione antioxidant defenses in gills of the freshwater catfish (Heteropneustes fossilis ) to short term elevated temperature显示文摘 | PARIHAR M S JAVERI T HEMNANI T | 1997 | Journal of Thermal Biology1997,22,2: | 1 |
| 18 | Endoscopic transoral excision of odontoid process in irreducible at- lantoaxial dislocation: our experience of 34 patients 显示文摘 | Yadav YR Madhariya SN Parihar VS | 2013 | J Neurol Surg A Cent Eur Neurosurg2013,74,3: | 1 |
| 19 | Endoscopic Vascular Decompression of the Trigeminal Nerve显示文摘 | Y. Yadav V. Parihar M. Agarwal S. Sherekar P. Bhatele | 2011 | Minim Invasive Neurosurg2011,,03: | 1 |
| 20 | Endo- scopic treatment of the suprasellar arachnoid cyst 显示文摘 | YADAV Y R PARIHAR V SINHA M | 2010 | Neurol India2010,58,2: | 1 |