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3篇 您的检索式:作者名="Suprabhat Mukherjee"
    题名 作者 年代 出处 被引量
1Potential use of polyphenol oxidases (PPO) in the bioremediation of phenolic contaminants containing industrial wastewater显示文摘Suprabhat Mukherjee Bikram Basak Biswanath Bhunia Apurba Dey Biswanath Mondal 2013Reviews in Environmental Science and Bio/Technology2013,,1:1
2In vitro antifilarial activity of Azadirachta indica aqueous extract through reactive oxygen species enhancement显示文摘Objective:To evaluate an aqueous preparation from the Azadirachta indica leaves(AEA) against Setaria cervi(S.cervi),a model filarial parasite.Methods:In vitro efficacy of AEA was evaluated against S.cervi through estimation of relative motility value,dye exclusion test and MTT assay.Visible morphological alterations were monitored using conventional microscopic techniques in microfilariae and haematoxylin-eosin stained sections of AEA-treated adults.Results:Enhancement of reactive oxygen species in S.cervi treated with AEA was established through alteration in the activity of glutathione S-transferase,superoxide dismutase,catalase,peroxidase and level of superoxide anion and reduced glutathione.Conclusions:In vitro filaricidal activity of AEA is possibly through disturbing redox homeostasis by down-regulating and altering the level of some key antioxidants and regulatory enzymes like reduced glutathione,glutathione S-transferase,superoxide dismutase,catalase and glutathione peroxidase of S.cervi.Niladri Mukherjee Prasanta Saini Suprabhat Mukherjee Priya Roy Santi P.Sinha Babu 2014Asian Pacific Journal of Tropical Medicine2014,7,11:0
3Molecular evidence on the occurrence of co-infection with Pichia guilliermondii and Wuchereria bancrofti in two filarial endemic districts of India显示文摘Background:Lymphatic filariasis(LF),a vector-borne parasitic disease,is endemic in several parts of India and mostly affects the poor or those with a low-income.The disease results in huge numbers of morbidities,disabilities,and deaths every year.Association of co-infection with other pathogens makes the condition more severe.Although co-infection is becoming a growing area of research,it is yet to emerge as a frontier research topic in filarial research specifically.This study reports the occurrence of a fungal infection in a large number of patients suffering from bancroftian filariasis in two districts of West Bengal,India.Methods:Nocturnal blood samples from filarial patients containing parasites and fungus were initially co-cultured,and further the fungus was isolated and characterized.Molecular identification of the isolate was carried out by PCR-based selective amplification and sequencing of highly-conserved D1/D2 region of 26S rDNA,whereas pathogenicity was determined by amplification of the RPS0 gene.A phylogenetic tree was constructed to study the relationship between the isolate and common pathogenic yeasts.The isolate was studied for antibiotic sensitivity,whereas morphological characterization was performed by microscopic techniques.Results:The isolate was identified as Pichia guilliermondii and this fungus was found to exist in co-infection with Wuchereria bancrofti in filarial patients.The fungus showed resistance to azole antifungals,griseofulvin,and,amphotericin B,whereas significant susceptibility was evident in cases of nystatin and cycloheximide.A total of 197 out of 222 patients showed this co-infection.Conclusion:This study revealed,for the first time,that P.guilliermondii exists as a co-infection in microfilaraemic individuals living in a filarial endemic zone.The findings are important and have relevance to human health,especially for filarial patients.Suprabhat Mukherjee Niladri Mukherjee Prasanta Saini Prajna Gayen Priya Roy Santi P Sinha Babu 2014Infectious Diseases of Poverty2014,3,1:0
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