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| 1 | Visual acuity and endothelial cell density with respect to the graft thickness in Descemet's stripping automated endothelial keratoplasty: one year results显示文摘AIM: To evaluate the visual acuity and endothelial cell density according to the thickness in Descemet's stripping automated endothelial keratoplasty(DSAEK)one year after surgery.METHODS: DSAEK patients' data were reviewed. Thirty seven eyes of 37 patients who underwent DSAEK for pseudophakic bullous keratopathy(PBK) were included in this study. Graft thickness was measured with optical coherence tomography(OCT) 12 mo after DSAEK. Eyes were divided into 3 groups based on the graft thickness:thick(>200 μm), medium-thick(150-200 μm) and thin(<150 μm). Best corrected visual acuity(BCVA),endothelial cells density(ECD) and complications were assessed and comparisons were done between groups.RESULTS: Median thickness of postoperative grafts was 188(range 73-317 μm). There was no significant difference in age, sex, preoperative BCVA, or follow-up period between DSAEK groups. At postoperative 12 mo,mean BCVA was 0.28±0.10 in thick graft group, 0.52±0.08 in medium-thick graft group, and 0.72 ±0.06 in thin graft group. Thin grafts showed better postoperative BCVA as compared with the medium-thick and thick grafts(P =0.001). Thick graft group had 1637.44 ±88.19-mm2,medium thick graft had 1764.50±34.28-mm2 and thin graft group had 1845.30 ±65.62-mm2. Thin graft group had better ECD at 12 mo after surgery(P =0.001).CONCLUSION: Thin grafts after DSAEK ensure better visual rehabilitation. Eyes with thin grafts had significantly lesser loss of ECD compared to eyes withmedium-thick and thick grafts one year after surgery. | Banu Torun Acar Mehmet Orcun Akdemir Suphi Acar | 2014 | International Journal of Ophthalmology(English edition)2014，7，6： | 3 |
| 2 | Potential effects of L-NAME on alcohol-induced oxidative stress显示文摘AIM: Nitric oxide (NO) is a highly reactive oxidant synthesized from L-arginine by nitric oxide synthase (NOS). NO may cause injury through the generation of potent radicals. Nwnitro-L-arginine methyl ester (L-NAME) is a non-selective inhibitor of NOS. We aimed to evaluate whether L-NAME treatment had protective effects against oxidative stress in rats intragastrically fed with ethanol during a 4 wk-period.METHODS: Thirty-six male Wistar rats were divided into 3 equal groups: group 1 (control group-isocaloric dextrose was given), group 2 (6 g/kg.d ethanol-induced group) and group 3 (both ethanol 6 g/kg.d and L-NAME 500 mg/L in drinking water-given group). Animals were sacrificed at the end of 4 wk-experimental period, and intracardiac blood and liver tissues were obtained. Biochemical measurements were performed both in plasma and in homogenized liver tissues. Alanine amino transferase (ALT), aspartate amino transferase (AST), malondialdehyde (MDA), NO, superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH) levels were measured by spectrophotometry.RESULTS: ALT and AST in group 2 (62 U/L and 128 U/L,respectively) were higher than those in group 1 (24 U/L and 38 U/L) and group 3 (37 U/L and 81 U/L) (P<0.001 for both).Plasma and tissue levels of MDA in group 2 (4.66 μmol/L and 0.55 nmol/mg protein) were higher than in group 1 (2.65 μmol/L and 0.34 nmol/mg protein) and group 3 (3.43 μmol/L and 0.36 nmol/mg protein) (P<0.001 for both). Plasma and liver tissue levels of NO in group 2 (54.67 μmol/L and 586.50 nmol/mg protein) were higher than in group 1 (34.67 μmol/L and 435.33 nmol/mg protein)and group 3 (27.50 μmol/L and 412.75 nmol/mg protein )(P<0.001 for both). Plasma and liver tissue SOD activities in group 2 (15.25 U/mL and 5.38 U/ mg protein,respectively) were lower than in group 1 (20.00 U/mL and 8.13 U/mg protein) and group 3 (19.00 U/mL and 6.93 U/mg protein) (P<0.001 for both). Plasma and liver tissue CAT activities in group 2 (145 U/mL and 37 U/ mg protein,respectively) were lower than in group 1 (176 U/mL and 73 U/mg protein) and group 3 (167 U/mL and 61 U/mg protein) (P<0.001 for both). Meanwhile, erythrocytes and liver tissue levels of GSH in group 2 (4.12 mg/g Hb and 5.38 nmol/mg protein, respectively) were lower than in group 1 (5.52 mg/g Hb and 4.49 nmol/mg protein) and group 3 (5.64 mg/g Hb and 4.18 nmol/mg protein) (P<0.001 for both).CONCLUSION: Our findings show that L-NAME may produce a restorative effect on ethanol-induced liver damage via decreasing oxidative stress and increasing antioxidant status. | Hafize Uzun Gonul Simsek Seval Aydin Ethem Unal Yesari Karter Nermin Karaturan Yelmen Suphi Vehid Asl Curgunlu Safiye Kaya | 2005 | World Journal of Gastroenterology2005，11，4： | 1 |
| 3 | Studies of the relationship between mineral matter and grinding properties for low-rank coals显示文摘 | U Suphi A Mustafa | 2004 | International Journal of Coal Geology2004，60，1： | 1 |
| 4 | The effect of different doses of subconjunctival bevacizumab injection on corneal neovascularization显示文摘 | Banu Torun Acar Elvin Halili Suphi Acar | 2013 | International Ophthalmology2013，，5： | 1 |
| 5 | Microalgae for a raacroenergy word显示文摘 | Suphi S Oncel | 2013 | Renewable andSustainable Energy Review2013，26，： | 1 |
| 6 | Studies of the relationship between mineral matter and grinding properties for low-rank coals 显示文摘 | Suphi Ural Mustafa Akyildiz | 2004 | International Journal of Coal Geology2004，60，： | 1 |
| 7 | Torque Distribution ina Six-Legged Robot显示文摘 | Mustafa Suphi Erden Kemal Leblebicioglu | 2007 | IEEE Transactions on Robotics2007，23，1： | 1 |
| 8 | Free gait geeration with reinforcement learning for a six-legged robot 显示文摘 | Mustafa Suphi Erden Kemal Leblebicioglu | 2008 | Robotics and Autonomous Systems2008，56，： | 1 |
| 9 | Studies of the relationship between mineral matter and grinding properties for low-rank coals显示文摘 | Suphi Ural Mustafa Akyildiz | 2004 | International Journal of Coal Geology2004，60，： | 1 |
| 10 | Comparison of fly ash properties from Afsin-Elbistan coal basin, Turkey 显示文摘 | SUPHI URAL | 2005 | Journal of Hazardous Materials2005，119，13： | 1 |
| 11 | Changes in endothelial cell density following penetrating keratoplasty and deep anterior lamellar keratoplasty显示文摘· AIM: To compare the corneal endothelial cell density (ECD) of clear grafts after penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK). · METHODS: The study included 44 and 54 patients treated with PK and DALK, respectively, between March 2006 and April 2010. Corneal ECD was examined using specular microscopy at postoperative 1, 3, 6, 12, and 18 months, and the values were compared. · RESULTS: Corneal ECD reduction in the PK group was 7.4%, 15.2%, 23.5%, and 28.9% at 3, 6, 12 and 18 months respectively after surgery, compared with 4.2 % in the first month (P <0.01). These figures were 3.0%, 6.7%, 7.2%, and 7.7% at 3, 6, 12 and 18 months respectively, compared with 2.2 % in the first month in the DALK group (P >0.05). · CONCLUSION: Compared with DALK,PK significantly reduced ECD of the clear grafts. These results suggest that survival of endothelial cells in grafts is better after DALK than after PK. · | Banu Torun Acar Ece Turan Vural Suphi Acar | 2011 | International Journal of Ophthalmology(English edition)2011，4，6： | 1 |
| 12 | Corneal endothelial cell loss in post-penetrating keratoplasty patients after cataract surgery: Phacoemulsification versus planned extracapsular cataract extraction显示文摘 | Banu Torun Acar Ibrahim Bulent Buttanri Mehmet Sahin Sevim Suphi Acar | 2011 | Journal of Cataract & Refractive Surgery2011，，8： | 1 |
| 13 | Use of Chromium Oxide and Alkane Indicator Methods for Determination of Feed Intake for Grazing Sheep显示文摘 | Selcuk Altacli Suphi Deniz | 2017 | Journal of Agricultural Science and Technology(A)2017，7，3： | 0 |
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