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102篇 您的检索式:作者名="Sunderman"
    题名 作者 年代 出处 被引量
1镁对镍、钴、锌、镉离子致蟾蜍胚胎毒性的影响显示文摘[目的 ]用FETAX设计 ,研究Mg2 + 对Ni2 + 、Co2 + 、Zn2 + 和Cd2 + 致Xenopus胚胎的胚胎毒性与致畸作用的影响。 [方法 ]在 7次检测中 ,分别于含Mg2 + 5个等级浓度 (0、6 2、62、62 0、62 0 0 μmol/L)的FETAX培养液中 ,设空白对照与加入NiCl2 (5 6μmol/L)、CoCl2 (180 0 μmol/L)、ZnCl2 (3 0 0 μmol/L)和CdCl2 (18μmol/L)的 2 5个组 ,每个组内的受精卵均经 5~10 1h孵育。在该检测中限定Mg2 + (62 0 μmol/L)为标准浓度。在该浓度时Ni2 + 、Co2 + 、Zn2 + 和Cd2 + 组胚胎死亡率 <10 % ,畸形率 >95 %。 [结果 ]对照组于标准浓度时平均畸形率为 (5 4± 1 3 ) % ,低于该等级的 62 μmol/L为 (3 2± 7) % ,≤ 6 2μmol/L为 10 0 %。表明Mg2 + 不足与补加可极显著地增强与降低胚胎畸形率及其严重程度与胚胎毒性 (P <0 0 0 0 1,ANO VA分析 )。 [结论 ]对此 ,推测这可能与涉及在两价金属离子转运之间的金属吸收、细胞通道或对关键性分子靶 (即DNA聚合酶 )结合的竞争有关。罗圣庆 Marilyn C.Plowman Sidney M.Hopfer F.William Sunderman JR 2002环境与职业医学2002,19,1:4
2Effects of teratogenic exposures to Zn2+, Cd2+, Ni2+, Co2+ and Cu2+ on metal- lothionein and metallothionein- mRNA contents of xenopus embryos显示文摘Sunderman F W Jr Plownam M C Kroftova O S 1995Pharmacol Toxicol1995,76,3:2
3Nickel carcinogenesis显示文摘KASPRZAK K S SUNDERMAN F W SALNIKOW K 2003Mutation Research2003,533,:1
4Nickel carcinogenesis显示文摘Kasprzak KS Sunderman FW Salnikow K 2003Mutat Res2003,533,12:1
5Recent advances in carcinogenesis显示文摘Sunderman FW Jr 1984Ann Lab Clin Sci1984,14,1:1
6Remote sensing approaches for reconstructing fire perimeters and burn severity mosaics in desert spring ecosystems显示文摘Sunderman S O Weisberg P J 2011Remote Sensing of Environment2011,115,9:1
7Nickel carcinogenesis 显示文摘Kasprzak K S Sunderman F W Salnikow K 2003Mutation Research2003,533,12:1
8Nickel carcinogenesis显示文摘KASPRZAK K S SUNDERMAN F W Jr SALNIKOW K 2003Mutat Res2003,533,12:1
9Nickel absorption and kinetics in human volunteers(42881)显示文摘Sunderman Jr FW Hopfer SM Sweeney KR 0,,:1
10Nickel carc-nogenesis显示文摘Kasprzak KS Sunderman Jr FW Salnikow K 2003Mutat Res2003,533,:1
11A survey of the accuracy of chemical analyses in clinical laboratories显示文摘Belk W P Sunderman F W 1947American Journal of Clinical Pathology1947,17,11:1
12Effects of teratogenic exposures to Zn2 + ,Cd2 +, Ni2 + , Co2 + and Cu2 + on metallothionein and metallothionein - mRNA contents of xenopus embryos 显示文摘Sunderman F W Jr Plownam M C Kroftova O S 1995Pharmacol Toxicol1995,76,3:1
13The history of proficiency testing/ quality control 显示文摘Sunderman F W 1992Clinical Chemistry1992,38,7:1
14Histopathology of sinonasal and lung cancers in nickel refinery worker 显示文摘Sunderman FW Morgan LG Andersen A 1989Ann Clin Lab Sci1989,19,1:1
15Forty-five years of proficiency testing 显示文摘Sunderman F W 1991Annals of Clinical and Laboratory Science1991,21,2:1
16Regulation of gene expression by metal inons: zinc finger-loop domains in hormone re- ceptors, transcription factors, and Proteins encoded oncogenes显示文摘Sunderman F W 1990Trace Elem Med1990,7,4:1
17The carcinogenicity of intravenous nickel carbonyl in rats 显示文摘LAU T J HACKETT R L SUNDERMAN F W JR 1972Cancer Res1972,32,10:1
18Effect of complete veneer crowns on the compressive strength of endodontically posterior teeth显示文摘Gelfand M Goldman M Sunderman EJ 1984J Prosthet Dent1984,52,6:1
19Regulation of gene expression by metal inons:zinc finger-loop domains in hormone receptors, tran seription factors,and proteins encoded oncogenes显示文摘Sunderman F W 1990Trace Elem Med1990,7,4:1
20Remote sensing approaches for recon- structing fire perimeters and burn severity mosaics in desert spring ecosystems显示文摘Sunderman SO Weisberg PJ 2011Remote Sensing of Environment2011,115,9:1
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