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| 1 | Response gene to complement 32 (RGC-32) expression on M2-polarized and tumor-associated macrophages is M-CSF-dependent and enhanced by tumor-derived IL-4显示文摘补充 32 的反应基因(RGC-32 ) 是涉及房间的增长,区别和迁居的一个房间周期管理者并且也在 angiogenesis 被含有。这里,我们证明在巨噬细胞的那 RGC-32 表情被 IL-4 导致并且由 LPS 减少了,显示在 RGC-32 表示和 M2 极化之间的一个连接。我们证明 RGC-32 的增加的表示或者激活的巨噬细胞,这蛋白质在压制支持 inflammatory cytokine IL-6 的生产并且支持反煽动性的调停人 TGF-β 的生产是特征的;。与一致在 vitro,数据, RGC-32 高级的联系肿瘤的巨噬细胞(TAM ) 快车,和这个表达式被导出肿瘤的腹水的液体以一种 M-CSF- 或 IL-4-dependent 方式导致。一起,这些结果为 M2 巨噬细胞极化作为一个标记建立 RGC-32 并且显示这蛋白质是为癌症免疫疗法的一个潜在的目标,指向联系肿瘤的巨噬细胞。 | Peng Zhao Daiqing Gao Qingjie Wang Bingfeng Song Qianqian Shao Jintang Sun Chunyan Ji Xingang Li Peng Li Xun Qu | 2015 | Cellular & Molecular Immunology2015，12，6： | 12 |
| 2 | Trends in Incidence Rates,Mortality Rates,and Age-Period-Cohort Effects of Cervical Cancer—China,2003–2017显示文摘Introduction:This study reported the trends and analyzed the age-period-cohort effects on the incidence and mortality rates of cervical cancer in China.Methods:The age-standardized incidence rate(ASIR)and mortality rate(ASMR)by Segi’s world standard population were calculated using qualified consecutive data from 22 cancer registries from 2003 to 2017 in China.We performed joinpoint analysis to describe the trends and age-period-cohort analysis to estimate the independent effects of age,period and cohort on trends in incidence and mortality rates of cervical cancer.Results:The ASIR and ASMR for cervical cancer in females over 20 years old increased during 2003−2017.For females<50 years,a decreasing trend in ASIR and a stable trend in ASMR were observed in urban areas after 2009.But the ASIR and ASMR kept increasing in rural areas during the whole period.For females>50 years,the ASIR and ASMR increased both in urban and rural areas.Age-period-cohort analysis showed increasing period effects on cervical cancer incidence and mortality during the whole period.The cohort effects exhibited a downward-upwarddownward pattern for the incidence(1918–1938,1938–1963,1963–1993)and mortality rates(1918–1943,1943–1963,1963–1993)in urban areas,a fluctuating pattern for incidence rate and a continuing downward pattern for mortality rate(1918–1993)in rural areas.Conclusions:The increases in cervical cancer incidence and mortality rates can be mostly explained by period effects.We observed decreases in risk for cervical cancer incidence and mortality in young female generations,which were more obvious in urban areas. | Kexin Sun Rongshou Zheng Lin Lei Siwei Zhang Hongmei Zeng Shaoming Wang Li Li Ru Chen Bingfeng Han Ji Peng Wenqiang Wei Jie He | 2022 | China CDC weekly2022，4，48： | 4 |
| 3 | Equilibrium model and algorithm of urban transit assignment based on augmented network显示文摘The passenger flow assignment problem for the urban transit network is relatively complicated due to the complexity of the network structure and many factors influencing the passengers' route and line choices. In the past three decades, many models have been proposed to solve the passenger flow assignment problem. However, the common-line problem remains challenging in transit flow assignment. In this paper, the characteristics of the urban transit network is analysed and a new technique of augmented network is proposed to represent the urban transit system. The purpose is to eliminate the complex common-line problem when modeling transit passenger flow assignment. Through this augmentation technique, the urban transit system can be represented by an augmented network-it then behaves like a simple network and can be used as a generalized network for traffic assignment or network analysis. This paper presents a user equilibrium model for the urban transit assignment problem based on such a technique. A numerical example is also provided to illustrate the approach. | SI BingFeng ZHONG Ming SUN HuiJun GAO ZiYou | 2009 | Science China(Technological Sciences)2009，52，11： | 3 |
| 4 | A new approach to the bicyclo[3.3.1]nonane framework of huperzine A-like molecules via palladium-catalyzed intramolecular γ-arylation显示文摘In our synthetic studies toward huperzine A, a diastereoselective α′-alkylation of the α-amido-γ-methyl hexenone 4 was realized through a dianion intermediate which significantly enhanced the reactivity. Under the attempted Heck reaction conditions, an unexpected and unprecedented palladium-catalyzed intramolecular γ-arylation of 3 was observed, which generated 18 with bicyclo[3.3.1]nonane framework in satisfactory yield. | DING Rui LU YunYu YAO HeQuan SUN BingFeng LIN GuoQiang | 2012 | Science China Chemistry2012，55，6： | 2 |
| 5 | Multifunctional poly ( d,1-lactide-co-glycolide )/montmorillonite ( PLGA/MMT ) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer 显示文摘 | Sun Bingfeng Balu Ranganathan Feng Si-Shen | 2008 | Biomaterials2008，29，4： | 1 |
| 6 | Trends in Incidence Rates,Mortality Rates,and Age-Period-Cohort Effects of Female Breast Cancer—China,2003-2017显示文摘Introduction:This study reported the trends in female breast cancer incidence and mortality rates in China,and analyzed the corresponding age-periodcohort effects.Methods:Data from 22 population-based cancer registries in China between 2003 and 2017 were analyzed.Age-standardized incidence rates(ASIR)and mortality rates(ASMR)were calculated using Segi’s world standard population.Joinpoint regression was employed to evaluate trends,and age-period-cohort effects were examined using the intrinsic estimator method.Results:The ASIR for female breast cancer exhibited a more rapid increase in rural areas compared to urban areas across all age groups.The most substantial increase was observed in the 20-34 age group in rural areas[annual percent change(APC)=9.0%,95%confidence interval(CI):7.0%-11.0%,P<0.001].The ASMR for females under 50 years old remained stable from 2003 to 2017 in both urban and rural areas.However,the ASMR for females over 50 in rural areas and those over 65 in urban areas demonstrated a significant increase,with the most pronounced increase observed among females over 65 in rural areas(APC=4.9%,95%CI:2.8%-7.0%,P<0.001).Age-period-cohort analysis revealed increasing period effects and decreasing cohort effects for female breast cancer incidence and mortality rates in both urban and rural settings.Notably,the cohort effect for incidence displayed a slight upward trend for females born between 1983 and 1992 in rural areas.Conclusions:Our study revealed a rapid increase in breast cancer incidence among younger generations and an accelerated mortality rate in older populations residing in rural areas.To effectively address the growing burden of female breast cancer in China,it is essential to develop and implement targeted intervention strategies. | Kexin Sun Lin Lei Rongshou Zheng Siwei Zhang Hongmei Zeng Shaoming Wang Li Li Ru Chen Bingfeng Han Ji Peng Wenqiang Wei Jie He | 2023 | China CDC weekly2023，5，15： | 1 |
| 7 | Muhifunctional poly(d,1-lactide co glycolide)/montmorillonite (PLGA/MMT) nanoparticles decorated by Trasiuzumab for targeted chemotherapy of breast cancer显示文摘 | Bingfeng Sun Balu Rangsmathan Si- Shen Feng | 2008 | Biomaterials2008，29，47： | 1 |
| 8 | Multifunctional poly (d,1-lactide-co-glycolide)/monntmorillonite (PLGA/MMT) nanopardcles decorated by Trastuzumab for targeted chemotherapy of breast cancer 显示文摘 | SUN Bingfeng BALU Ranganathan FENG Si-Shen | 2008 | Biomaterials2008，29，4： | 1 |
| 9 | An efficient total synthesis of (-)-epothilone B 显示文摘 | WANG Jie SUN Bingfeng CUI Kai | 2012 | Org Lett2012，14，24： | 1 |
| 10 | Multifunctional poly ( D, L-lactide-co-glycolide )/montmorillonitte (PLGA/MMT) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer 显示文摘 | Sun Bingfeng Ranganathan Balu Feng Si-Shen | 2008 | Biomaterials2008，29，： | 1 |
| 11 | Incidence and Mortality of Cancers in Female Genital Organs—China,2022显示文摘Introduction:This study presented the incidence and mortality rates of cancers affecting the female genital organs in China,along with their trends spanning from 2010 to 2018.Methods:700 population-based cancer registries provided relevant cancer incidence and mortality data for the year 2018.Among these,106 registries had continuous monitoring data suitable for trend analysis from 2010 to 2018.We focused specifically on cancers affecting female genital organs(ICD10=C51-C54,C56)and projected their incidences and mortalities in China for 2022 based on data from 2018 and the trends observed from 2010 to 2018.Age-standardized incidence rate(ASIR)and mortality rate(ASMR)were calculated using Segi’s world standard population.Results:In 2022,there were an estimated 296,300 new cases and 104,900 deaths from female cancers in China.ASIRs for vulva(C51),vagina(C52),cervix uteri(C53),corpus uteri(C54),and ovary(C56)were 0.32,0.23,13.83,6.84,and 5.68 per 100,000 population.ASIRs for corpus uteri and ovary cancers were higher in urban areas.ASMRs for vulva,vagina,cervix,corpus uteri,and ovary cancers were 0.14,0.08,4.54,1.05,and 2.64 per 100,000 population,respectively.ASMR for ovarian cancer was higher in urban areas.ASIRs and ASMRs for most female genital organ cancers increased from 2010 to 2018,although the rate of increase for vulvar and cervical cancers in rural areas has slowed recently.Conclusions:Tailored cancer prevention and control programs specific to each region are necessary to address the growing disease burden. | Kexin Sun Bingfeng Han Hongmei Zeng Shaoming Wang Li Li Ru Chen Rongshou Zheng Wenqiang Wei | 2024 | China CDC weekly2024，6，10： | 0 |
| 12 | Thickness-driven spin reorientation transition in ultrathin films显示文摘We review recent studies by different experimental means of ultrathin films,exhibiting thickness-driven spin reorientation transitions(SRTs).The stage is set by determining,via phenomenological thermodynamic description,of the relevant phase diagrams for the possible types of SRT with and without applied magnetic field.Suitable representation may be chosen such that best use is made of the linear character(under thickness variation) of the system's path in anisotropy space.The latter involves higher-order bulk and surface anisotropies in a substantial way.We examine sensitive experimental techniques for the detection and quantification of SRTs,such as hysteresis measurements with magneto-optical Kerr effect(MOKE),micromagnetic studies utilizing scanning electron microscopy with polarization analysis(SEMPA),photoemission electron microscopy(PEEM) and spin-polarized low-energy electron microscopy(SPLEEM) as well as ac magnetic susceptibility measurements via MOKE.Key issues are conclusively discussed including the identification of reliable experimental fingerprints about whether a given SRT proceeds via a phase of coexistence or via a cone(canted) phase.We demonstrate how the application of the general theoretical ideas to carefully designed measurements leads to the determination of the most important material parameters in any ultrathin-film SRT,namely,the surface(interface) magnetic anisotropy constants.The review concludes by our personal outline for future promising work on SRTs. | MIAO BingFeng MILLEV YonkoTimtchev SUN Liang YOU Biao ZHANG Wei DING HaiFeng | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，1： | 0 |
| 13 | 2-2 Lifetime Measurement of the Low-lying Excited States 7/21^+in^87Zr显示文摘Lifetime measurements of low-lying excited states in^87Zr have been performed viaβ-γcoincidences.The 127 MeV^32S beam was delivered from the Sector-Focusing Cyclotron(SFC)of the Heavy Ion Research Facility in Lanzhou(HIRFL).The parent nuclei^87Nb were produced by the reaction 58Ni(32S,2p1n),at a beam energy 127 MeV through a 8 um Al degrader.A 200ug/cm^2 layer of 58Ni evaporated onto a 200ug/cm^2 thick carbon foil was employed as the target.After evaporation residues were separated from the projectile beams by the gas-filled recoil separator SHANS[1],the nuclei of interest 87Zr can be obtained with a higher purity and then were implanted into a 300um silicon detector. | Qiang Yunhua Liu Minliang Zhou Xiaohong Wang Jianguo Guo Song Wang Kailong Lv Bingfeng Zheng Yong Gan Zaiguo Ma Long Yang Huabin Ding Bing Huang Tianheng Sun Mingdao | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
| 14 | Combat network link prediction based on embedding learning显示文摘Link prediction of combat networks is of significant military value for precisely identifying the vital infrastructure of the enemy target and optimizing the operational plan of our side.Due to the profound uncertainty in the battleground circumstances, the acquired topological information of the opponent combat network always presents sparse characteristics. To solve this problem, a novel approach named network embedding based combat network link prediction(NECLP) is put forward to predict missing links of sparse combat networks. First,node embedding techniques are presented to preserve as much information of the combat network as possible using a low-dimensional space. Then, we put forward a solution algorithm to predict links between combat networks based on node embedding similarity. Last, massive experiments are carried out on a real-world combat network case to verify the validity and practicality of the proposed NECLP. This paper compares six baseline methods, and experimental results show that the NECLP has outstanding performance and substantially outperforms the baseline methods. | SUN Jianbin LI Jichao YOU Yaqian JIANG Jiang Ge Bingfeng | 2022 | Journal of Systems Engineering and Electronics2022，33，2： | 0 |
| 15 | 2-2 Lifetime Measurements of the Low-lying Excited States in 87 Zr and 87 Nb显示文摘Lifetime measurements of low-lying excited states in 87Zr and 87Nb have been performed via and coincidences. The 124 MeV 32S beam was delivered from the Sector-Focusing Cyclotron (SFC) of the Heavy Ion R-esearch Facility in Lanzhou (HIRFL). The parent nuclei 87Nb and 87Mo were produced by the respective reactions 58Ni (32S, 3p) and 58Ni (32S, 2p1n), at a beam energy 100 MeV through the 8 m Al degrader. | Qiang Yunhua Liu Minliang Zhou Xiaohong Wang Jianguo Wang Kailong Lv Bingfeng Zheng Yong Gan Zaiguo Zhang Zhiyuan Ma Long Yang Huabin Yu Lin Jiang Jian Sun Mingdao | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
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