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| 1 | Response gene to complement 32 (RGC-32) expression on M2-polarized and tumor-associated macrophages is M-CSF-dependent and enhanced by tumor-derived IL-4显示文摘补充 32 的反应基因(RGC-32 ) 是涉及房间的增长,区别和迁居的一个房间周期管理者并且也在 angiogenesis 被含有。这里,我们证明在巨噬细胞的那 RGC-32 表情被 IL-4 导致并且由 LPS 减少了,显示在 RGC-32 表示和 M2 极化之间的一个连接。我们证明 RGC-32 的增加的表示或者激活的巨噬细胞,这蛋白质在压制支持 inflammatory cytokine IL-6 的生产并且支持反煽动性的调停人 TGF-β 的生产是特征的;。与一致在 vitro,数据, RGC-32 高级的联系肿瘤的巨噬细胞(TAM ) 快车,和这个表达式被导出肿瘤的腹水的液体以一种 M-CSF- 或 IL-4-dependent 方式导致。一起,这些结果为 M2 巨噬细胞极化作为一个标记建立 RGC-32 并且显示这蛋白质是为癌症免疫疗法的一个潜在的目标,指向联系肿瘤的巨噬细胞。 | Peng Zhao Daiqing Gao Qingjie Wang Bingfeng Song Qianqian Shao Jintang Sun Chunyan Ji Xingang Li Peng Li Xun Qu | 2015 | Cellular & Molecular Immunology2015，12，6： | 12 |
| 2 | MiR-375 suppresses invasion and metastasis by direct targeting of SHOX2 in esophageal squamous cell carcinoma显示文摘食道的有鳞的房间癌(ESCC ) 是在中国的最普通的组织学的类型。MicroRNAs 内长地在哺乳动物被表示并且由指向潜在的下游的基因在肿瘤侵略和转移起一个重要作用。在现在的学习, microarray 分析证明那 miR-375 表情是显然在 ESCC 的 downregulated 与那相比在正常食道的上皮纸巾。然后,酶记者试金证明 SHOX2 是 miR-375 的直接下游的目标,这个相互作用被营救实验证实。量的聚合酶链反应结果也证明那 SHOX2 表情是在 ESCC 房间和纸巾的 upregulated。进一步的分析证明 SHOX2 在 vivo 并且在 vitro 导致了 ESCC 的增长,侵略,和转移。而且,在 miR-375 和 SHOX2 之间的相互作用影响了 epithelial-to-mesenchymal 转变。我们断定 miR-375 可以由直接指向 SHOX2 压制 ESCC 的侵略和转移。miR-375/SHOX2 轴可以是为 ESCC 的一个新奇治疗学的目标。 | Jun Yi Li Jin Jing Chen BingFeng Zhenyue He Longbang Chen Haizhu Song | 2017 | Acta Biochimica et Biophysica Sinica2017，49，2： | 11 |
| 3 | Analysis and Suggestions of the Satisfaction of Postgraduate Education in Engineering Universities —Take Harbin Institute of Technology (Weihai) for Example显示文摘Accelerating the development of students is the basic goal of postgraduate talent cultivation.The final research results,employment situation and satisfaction of postgraduate students with school education are more important indicators of the quality of talent cultivation in a university.For having a deeper understanding of the satisfaction of postgraduates in Harbin Institute of Technology(Weihai)in terms of motivation,tutor situation,management service and employment situation,a questionnaire survey was conducted on postgraduates.The survey results show that the overall satisfaction of postgraduates is high.In terms of studying motivation,most postgraduates think that their majors are more related to employment;in terms of professors,most of them can get along well with their professors and learn from the advantages of their professors;in terms of school management,they respond well to the'library',but think that the'dormitory'and'canteen'need further improvement;in terms of employment,most of postgraduates choose to be employed,while a few of them choose to further their studies,most of which have applied to study in domestic or foreign universities. | Lianmao Yang Yiqun Liu Xiaoguo Song Bingfeng Liu | 2022 | 教育研究前沿(中英文版)2022，12，2： | 0 |
| 4 | 2-2 Lifetime Measurement of the Low-lying Excited States 7/21^+in^87Zr显示文摘Lifetime measurements of low-lying excited states in^87Zr have been performed viaβ-γcoincidences.The 127 MeV^32S beam was delivered from the Sector-Focusing Cyclotron(SFC)of the Heavy Ion Research Facility in Lanzhou(HIRFL).The parent nuclei^87Nb were produced by the reaction 58Ni(32S,2p1n),at a beam energy 127 MeV through a 8 um Al degrader.A 200ug/cm^2 layer of 58Ni evaporated onto a 200ug/cm^2 thick carbon foil was employed as the target.After evaporation residues were separated from the projectile beams by the gas-filled recoil separator SHANS[1],the nuclei of interest 87Zr can be obtained with a higher purity and then were implanted into a 300um silicon detector. | Qiang Yunhua Liu Minliang Zhou Xiaohong Wang Jianguo Guo Song Wang Kailong Lv Bingfeng Zheng Yong Gan Zaiguo Ma Long Yang Huabin Ding Bing Huang Tianheng Sun Mingdao | 2016 | IMP & HIRFL Annual Report2016，，1： | 0 |
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