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| 1 | FY-4A/GIIRS Temperature Validation in Winter and Application to Cold Wave Monitoring显示文摘In order to improve the operational application ability of the Fengyun-4A(FY-4A)new sounding dataset,in this paper,validation of the FY-4A Geosynchronous Interferometric Infrared Sounder(FY-4A/GIIRS)temperature was carried out using the balloon sounding temperature from meteorological sounding stations.More than 350,000 samples were obtained through time–space matching,and the results show that the FY-4A/GIIRS temperature mean bias(MB)is 0.07°C,the mean absolute error(MAE)is 1.80°C,the root-mean-square error(RMSE)is 2.546°C,and the correlation coefficient(RR)is 0.95.The FY-4A/GIIRS temperature error is relatively larger in the upper and lower troposphere,and relatively smaller in the middle troposphere;that is,the temperature at 500 hPa is better than that at 850 hPa.The temporal variation is smaller in the upper and middle troposphere than in the lower troposphere.The reconstruction of missing data of FY-4A/GIIRS temperature in cloudy areas is also carried out and the results are evaluated.The spatial distribution of reconstructed FY-4A/GIIRS temperature and the fifth generation ECMWF reanalysis(ERA5)data is consistent and completely retains the minimum temperature center with high precision of FY-4A/GIIRS.There are more detailed characteristics of intensity and position at the cold center than that of the reanalysis data.Therefore,an operational satellite retrieval temperature product with time–space continuity and high accuracy is formed.The reconstructed FY-4A/GIIRS temperature is used to monitor a strong cold wave event in November 2021.The results show that the product effectively monitors the movement and intensity of cold air activities,and it also has good indication for the phase transition of rain and snow triggered by cold wave. | Suling REN Jianying JIANG Xiang FANG Hui LIU Zhiqiang CAO | 2022 | Journal of Meteorological Research2022，36，4： | 3 |
| 2 | Impact of tropical cyclone development on the instability of South Asian High and the summer monsoon onset over Bay of Bengal显示文摘 | Guoxiong Wu Suling Ren Jianmin Xu Dongxiao Wang Qing Bao Boqi Liu Yimin Liu | 2013 | Climate Dynamics (-)2013，，9： | 1 |
| 3 | Impact of tropical cyclone development on the instability ofSouth Asian high and the summer monsoon onset over bay ofBengal显示文摘 | WU GUOXIONG REN SULING XU JIANMIN 2013 | 2013 | Climate Dynamics2013，41，910： | 1 |
| 4 | Global Rainstorm Disaster Risk Monitoring Based on Satellite Remote Sensing显示文摘Methods of rainstorm disaster risk monitoring(RDRM)based on retrieved satellite rainfall data are studied.Due to significant regional differences,the global rainstorm disasters are not only affected by geography(such as topography and surface properties),but also by climate events.It is necessary to study rainstorm disaster-causing factors,hazard-formative environments,and hazard-affected incidents based on the climate distribution of precipitation and rainstorms worldwide.According to a global flood disaster dataset for the last 20 years,the top four flood disaster causes(accounting for 96.8%in total)related to rainstorms,from most to least influential,are heavy rain(accounting for 61.6%),brief torrential rain(16.7%),monsoonal rain(9.4%),and tropical cyclone/storm rain(9.1%).A dynamic global rainstorm disaster threshold is identified by using global climate data based on 3319 rainstorm-induced floods and rainfall data retrieved by satellites in the last 20 years.Taking the 7-day accumulated rainfall,3-and 12-h maximum rainfall,24-h rainfall,rainstorm threshold,and others as the main parameters,a rainstorm intensity index is constructed.Calculation and global mapping of hazard-formative environmental factor and hazard-affected body factor of rainstorm disasters are performed based on terrain and river data,population data,and economic data.Finally,a satellite remote sensing RDRM model is developed,incorporating the above three factors(rainstorm intensity index,hazard-formative environment factor,and hazard-affected body factor).The results show that the model can well capture the rainstorm disasters that happened in the middle and lower reaches of the Yangtze River in China and in South Asia in 2020. | Suling REN Xiuzhen HAN Jun YANG Shihao TANG Yang ZHANG Tianchan SHAN Cheng LIU | 2022 | Journal of Meteorological Research2022，36，1： | 0 |
| 5 | Intratumoral CD103+CD8+T cells predict response to neoadjuvant chemoimmunotherapy in advanced head and neck squamous cell carcinoma显示文摘Background Immune cell heterogenicity is known to determine the therapeutic response to cancer progression.Neoadjuvant chemoimmunotherapy(NACI)has shown clinical benefits in some patients with advanced head and neck squamous cell carcinoma(HNSCC),but the underlying mechanism behind this clinical response is unknown.The efficacy of NACI needs to be potentiated by identifying accurate biomarkers to predict clinical responses.Here,we attempted to identify molecules predicting NACI response in advanced HNSCC.Methods We performed combined single-cell RNA sequencing(scRNA-seq)and multiplex immunofluorescence(mIHC)staining with tumor samples derived from NACI-treated HNSCC patients to identify a new tumor-infiltrating cell(TIL)subtype,CD103+CD8+TILs,associated with clinical response,while both in vitro and in vivo assays were carried out to determine its antitumor efficiency.The regulatory mechanism of the CD103+CD8+TILs population was examined by performing cell-cell interaction analysis of the scRNA-seq data and spatial analysis of the mIHC images.Results We established intratumoral CD103+CD8+TILs density as a determinant of NACI efficacy in cancers.Our scRNA-seq results indicated that the population of CD103+CD8+TILs was dramatically increased in the responders of NACI-treated HNSCC patients,while mIHC analysis confirmed the correlation between intratumoral CD103+CD8+TILs density and NACI efficacy in HNSCC patients.Further receiver operating characteristic curve analysis defined this TIL subset as a potent marker to predict patient response to NACI.Functional assays showed that CD103+CD8+TILs were tumor-reactive T cells,while programmed cell death protein-1(PD-1)blockade enhanced CD103+CD8+TILs cytotoxicity against tumor growth in vivo.Mechanistically,targeting the triggering receptor expressed on myeloid cells 2-positive(TREM2+)macrophages might enhance the population of CD103+CD8+TILs and facilitate antitumor immunity during NACI treatment.Conclusions Our study highlights the impact of intratumoral CD103+CD8+TILs density on NACI efficacy in different cancers,while the efforts to elevate its population warrant further clinical investigation. | Siqi Ren Tianjun Lan Fan Wu Suling Chen Xue Jiang Chuying Huo Zitian Li Shule Xie Donghui Wu Ruixin Wang Yanyan Li Lin Qiu Guoxin Huang Shurui Li Xiaojuan Wang Meifeng Cen Tingting Cai Zhaoyu Lin Jinsong Li Bowen Li | 2023 | Cancer Communications2023，43，10： | 0 |
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