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| 1 | Emergency resection surgery for colorectal cancer: Patterns of recurrent disease and survival显示文摘AIM To evaluate prognostic pathological factors associated with early metachronous disease and adverse longterm survival in these patients.METHODS Clinical and histological features were analysed retrospectively over an eight-year period for prognostic impact on recurrent disease and overall survival in patients undergoing curative resection of a primary colorectal cancer. RESULTS A total of 266 patients underwent curative surgery during the study period. The median age of the study cohort was 68 year(range 26 to 91) with a followup of 7.9 years(range 4.6 to 12.6). Resection was undertaken electively in 225(84.6%) patients and emergency resection in 35(13.2%). Data on timing of surgery was missing in 6 patients. Recurrence was noted in 67(25.2%) during the study period and was predominantly early within 3 years(82.1%) and involved hepatic metastasis in 73.1%. Emergency resection(OR = 3.60, P = 0.001), T4 stage(OR = 4.33, P < 0.001) and lymphovascular invasion(LVI) (OR = 2.37, P = 0.032) were associated with higher risk of recurrent disease. Emergency resection, T4 disease and a high lymph node ratio(LNR) were strong independent predictors of adverse long-term survival. CONCLUSION Emergency surgery is associated with adverse disease free and long-term survival. T4 disease, LVI and LNR provide strong independent predictive value of longterm outcome and can inform surveillance strategies to improve outcomes. | Joe Littlechild Muneer Junejo Anne-Marie Simons Finlay Curran Darren Subar | 2018 | World Journal of Gastrointestinal Pathophysiology2018，9，1： | 5 |
| 2 | Laparoscopic Versus Open Appendectomy in Adults with Complicated Appendicitis: Systematic Review and Meta-analysis显示文摘 | Georgios Markides Daren Subar Kallingal Riyad | 2010 | World Journal of Surgery2010，，9： | 2 |
| 3 | Fruit,vegetable,and cancer prevention:a review of epidemiological evidence显示文摘 | Block G Patterson B Subar A | 1992 | Nutr Cancer1992，18，： | 1 |
| 4 | Reducing nasopharyngeal trauma:the urethral catheter-Assisted nasotracheal intubation technique显示文摘 | Wong A Subar P Witherell H | 2011 | Anesthesia Pro2011，58，1： | 1 |
| 5 | Fruit, vegetables, and cancer prevention : a review of the epidemiological evidence 显示文摘 | Block G Patterson B Subar A | 1992 | Nutr Cancer1992，18，3： | 1 |
| 6 | Control of enzymatic browning of foods显示文摘 | PILIZOTA V SUBARIC D | 1998 | Food Technology and Biotechnology1998，36，3： | 1 |
| 7 | Design and seren?dipity in establishing a large cohort with wide dietary intake distri?butions : the National Institutes of Health-American Association of Retired Persons Diet and Health Study显示文摘 | Schatzkin A Subar AF Thompson FE | 2001 | AmJ Epidemiol2001，154，12： | 1 |
| 8 | A compara- tive study of exemestane versus anastrozole in patients with postmenopausal breast cancer with visceral metasta-ses显示文摘 | Campos SM Guastalla JP Subar M | 2009 | Clin Breast Cancer2009，9，1： | 1 |
| 9 | Coffee consumption and the risk of overall and fatal prostate cancer in the NIH-AARP Diet and Health Study显示文摘 | BosireC Stampfer MJ Subar AF | 2013 | Cancer Causes Control2013，24，8： | 1 |
| 10 | Nasal septal deformities in ear,nose, and throat patients: An international study显示文摘 | Mladina R Cujic E Subaric M | 2008 | Am J Otolaryngol2008，29，2： | 1 |
| 11 | Ameri- cans do not meet federal dietary recommendations 显示文摘 | Krebs-Smith SM Guenther PM Subar AF | 2010 | Journal of Nutrition2010，140，10： | 1 |
| 12 | Use of vitamin, mineral, nonvitamin, and nonmineral supplements in the United States: the 1987,1992, and 2000 National Health Interview Survey results显示文摘 | MILLEN A E DODD K W SUBAR A F | 2004 | J Am Diet Assoc2004，104，： | 1 |
| 13 | Fruit,vegetable,and cancer prevention:a review of epidemiological evidence显示文摘 | Block G Patterson B Subar A | 1992 | Nutr Cancer1992，18，1： | 1 |
| 14 | Control of enzymatic browning of foods 显示文摘 | Pilizota V Subaric D | 1998 | Food Technology And Bioteehnology1998，36，3： | 1 |
| 15 | Effect of chitosan on lingual hemostasis in rabbits with platelet dysfunction induced by epoprostenol 显示文摘 | Klokkevold PR Subar P Fukayama H | 1992 | J Oral Maxillofac surg1992，50，1： | 1 |
| 16 | Association between prescription co-payment amount and compliance with adjuvant hormonal therapy in women with early-stage breast cancer显示文摘 | Neugut AI Subar M Wilde ET | 2011 | J Clin Oncol2011，29，18： | 1 |
| 17 | A prospective study ofmeat and fat intake in relation to small intestinal cancer 显示文摘 | Cross AJ Leitzmann MF Subar AF | 2008 | CancerRes2008，68，22： | 1 |
| 18 | Fruit and vegetable intake and esophageal cancer in a large prospeetive cohort study显示文摘 | Freedman ND Park Y Subar AF | 2007 | Int J Cancer2007，121，12： | 1 |
| 19 | Laparoscopic versus open appendec- tomy in adults with complicated appendicitis:systematic review and meta-analysis显示文摘 | Markides G Subar D Riyad K | 2010 | World J Surg2010，31，4： | 1 |
| 20 | Effect of chitosan on lingual hemostasis in rabbits with platelet dysfunction induced by epoprostenol显示文摘 | Klokkevold PR Subar P Fukayama H | 1992 | J Oral Max-illofac Surg1992，50，1： | 1 |
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