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80篇 您的检索式：作者名="Styner"

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	题名	作者	年代	出处	被引量
1	Transgenic rhesus monkeys carrying the human MCPH1 gene copies show human-like neoteny of brain development显示文摘Brain size and cognitive skills are the most dramatically changed traits in humans during evolution and yet the genetic mechanisms underlying these human-specific changes remain elusive.Here,we successfully generated 11 transgenic rhesus monkeys(8 first-generation and 3 second-generation)carrying human copies of MCPH1,an important gene for brain development and brain evolution.Brain-image and tissue-section analyses indicated an altered pattern of neural-cell differentiation,resulting in a delayed neuronal maturation and neural-fiber myelination of the transgenic monkeys,similar to the known evolutionary change of developmental delay(neoteny)in humans.Further brain-transcriptome and tissue-section analyses of major developmental stages showed a marked human-like expression delay of neuron differentiation and synaptic-signaling genes,providing a molecular explanation for the observed brain-developmental delay of the transgenic monkeys.More importantly,the transgenic monkeys exhibited better short-term memory and shorter reaction time compared with the wild-type controls in the delayed-matching-to-sample task.The presented data represent the first attempt to experimentally interrogate the genetic basis of human brain origin using a transgenic monkey model and it values the use of non-human primates in understanding unique human traits.	Lei Shi Xin Luo Jin Jiang Yongchang chen Cirong Liu Ting Hu Min Li Qiang Lin Yanjiao Li Jun Huang Hong Wang Yuyu Niu Yundi Shi Martin Styner Jianhong Wang Yi Lu Xuejin Sun Hualin Yu Weizhi Ji Bing Su	2019	National Science Review2019，6，3：	12
2	Image analysis and superimposition of 3-dimensional cone-beam computed tomography models 显示文摘	Cevidanes LH Styner MA Proffit WR	2006	Am J Orthod Dentofacial Orthop2006，129，5：	1
3	Pharyngeal airway vol- ume and shape from cone-beam computed tomography:relationshipto facial morphology显示文摘	Grauer D Cevidanes LS Styner MA	2009	Am J Orthod Dentofacial Orthop2009，136，6：	1
4	Parametric estimate of intensity inhomogeneities applied to MRI显示文摘	STYNER M BRECHBUHLER C SZEKELY G	2000	I EEE Trans on Medi- cal Imaging2000，19，3：	1
5	Comparison and evaluation of methods for liver segmentation from CT datasets显示文摘	Heimann T van Ginneken B Styner M A	2009	IEEE Transactions on Medical Imaging2009，28，8：	1
6	Evaluation of 2d/3d bias correction with 1 +les-optimization显示文摘	Styner M Gerig G		0，，：	1
7	Comparison and evaluation of methods for liver segmentation from CT datasets显示文摘	Heimann T Ginneken B Styner MA	2009	IEEE Transactions on Medical Imaging2009，28，8：	1
8	Comparison and evaluation of methods for liver segmentation from CT datasets 显示文摘	Heimann T van Ginneken B Styner M A	2009	IEEE Transactions on Medical Imaging (S0278-0062)2009，28，8：	1
9	Pharyngeal airway volume and shape from cone-beam computed to-mography:Relationship to facial morphology显示文摘	Grauer D Cevidanes LS Styner MA		0，，06：	1
10	Parametric estimate of intensity inhomogeneities applied to MRI显示文摘	Styner M Brechbuhler C Szckely G	2000	IEEE Transactions on Medical Imaging2000，19，3：	1
11	Statistical Deformable Bone Models for Robust 3D Surface Extrapolation from Sparse Data 显示文摘	Rajamani M Styner H Talib	2007	Medical Image Analysis2007，，11：	1
12	Comparison and evaluation of methods for liver segmentation from CT datasets显示文摘	Heimann T van Ginneken B Styner MA Arzhaeva Y Aurich V Bauer C Beck A Becket C Beichel R Bekes G Bello F Binnig G Bischof H Bornik A Cashman PM Chi Y Cordova A Dawant BM Fidrich M Furst JD Furukawa D Grenacher L Hornegger J Kainmuller D Kitney RI Kobatake H Lamecker H Lange T Lee J Lennon B Li R Li S Meinzer HP Nemeth G Raicu DS Rau AM van Rikxoort EM Rousson M Rusko L Saddi KA Schmidt G Seghers D Shimizu A Slagmolen P Sorantin E Soza G Susomboon R Waite JM Wimmer A Wolf I	2009	IEEE Transactions on Medical Imaging2009，28，8：	1
13	Parametric estimate of intensity inhomogeneities applied to MRI 显示文摘	Styner M Brechbuhler C Szekely G	2000	IEEE Trans Med Imaging2000，19，3：	1
14	Pharyngeal airway volume and shape from cone-beam computed tomography: relationship to facial morphology显示文摘	Grauer D Cevidanes LS Styner MA	2009	Am J Orthod Dentofacial Orthop2009，136，6：	1
15	Pharyngeal airway volume and shape from cone-beam computed tomography: relationship to facial morphology显示文摘	Grauer D Cevidanes LS Styner MA	2009	Am J Orthod Dentofacial Orthop2009，136，6：	1
16	Image analysis andsuperimposition of 3-dimensional cone-beam computedtomography models显示文摘	Cevidanes LH Styner MA Proffit WR	2006	Am J Orthod Dentofacial Orthop2006，129，5：	1
17	Comparison and evaluation of methods for liver segmentation from CT datasets 显示文摘	Heimann T Ginneken van B Styner M A	2009	IEEE Transactions on Medical Imaging2009，28，8：	1
18	Pharyngeal airway vol- ume and shape from cone-beam computed tomography:relationship to facial morphology 显示文摘	Grauer D Cevidanes LS Styner MA	2009	Am J Orthod Dentofacial Orthop2009，136，6：	1
19	White matter hyperintensities, systemic inflammation, brain growth and cognitive functions in children exposed to air pollu- tion 显示文摘	Calderon-Garciduefias L Mora-Tiscarefio A Styner M	2012	J Alzheimers Dis2012，31，1：	1
20	Parametric estimate of intensity inhomogeneities applied to MRI显示文摘	Brechbtühler C Székely G	2000	IEEE Trans Med Imaging2000，19，3：	1

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