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| 1 | Macrophage polarization in response to wear particles in vitro显示文摘全部的联合代替是为有停用关节炎和联合机能障碍的病人的治疗的一个高度成功的外科的过程。随着时间的过去,与活动的高水平和关节的用法,然而植入穿粒子从明白表示的表面被产生。这些穿粒子能在 implant (periprosthetic osteolysis ) 附近导致煽动性的反应,和随后的骨头再吞的激活。单核白血球 / 巨噬细胞系的房间安排这长期的煽动性的回答,它被支持 inflammatory (M1 ) 统治巨噬细胞显型而非一反煽动性的支持织物的愈合(M2 ) 巨噬细胞显型。当它被显示出时,那 interleukin-4 (IL-4 ) 有选择地极化向支持骨头愈合的 M2 反煽动性的显型的巨噬细胞,而非发炎,很少对这在通过 IL-4 的极化在哪个是很有效的在发生或调节的时间功课被知道。这个工作的目标是与 polymethyl methacrylate (PMMA ) 的联合响应挑战学习鼠科的巨噬细胞极化和 cytokine 版本的时间功课粒子, lipopolysaccharide (LPS ) 和在 vitro 的 IL-4。有 IL-4 的质问粒子的单核白血球 / 巨噬细胞的处理导致了支持 inflammatory cytokines 和可诱导的氮的氧化物 synthase (iNOS ) 的起始的抑制生产和随后的极化进 M2 反煽动性的显型。当 IL-4 在 PMMA 粒子挑战前被交付时,这结果被优化,到 M1 显型而非到未遂(M0 ) 巨噬细胞。这极化的效果在一堂 5 天的时间功课上被支撑。进 M2 显型的 M1 巨噬细胞的极化可以是策略减轻穿粒子联系 periprosthetic osteolysis。 | Joseph K Antonios Zhenyu Yao Chenguang Li Allison J Rao Stuart B Goodman | 2013 | Cellular & Molecular Immunology2013，10，6： | 10 |
| 2 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet2001，，9286： | 4 |
| 3 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet . 2001 (9286)2001，，9286： | 4 |
| 4 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | 2001 (9286)2001，，9286： | 4 |
| 5 | Efficacy of postoperative blood salvage follwing total hip arthroplasty in patients with and without deposited autologous units 显示文摘 | David Grosvenor Varish Goyal BS Stuart Goodman | 2000 | J Bone Joint Surg2000，82，： | 1 |
| 6 | Macrophage polarization: An opportunity for improved outcomes in biomaterials and regenerative medicine显示文摘 | Bryan N. Brown Buddy D. Ratner Stuart B. Goodman Salomon Amar Stephen F. Badylak | 2012 | Biomaterials2012，，15： | 1 |
| 7 | A conical-collared intramedullary stem can improve stress transfer and limit micromotion显示文摘 | Jay A. Mandell Dennis R. Carter Stuart B. Goodman David J. Schurman Gary S. Beaupré | 2004 | Clinical Biomechanics2004，，7： | 1 |
| 8 | Novel use of a custom stereotactic frame for placement of depth electrodes for epilepsy monitoring显示文摘 | Stuart RM Goodman RR | 2008 | Neurosurg Focus2008，25，3： | 1 |
| 9 | Specific amplification and restriction polymorphisms of the cyanobacterial rRNA operon spacer region显示文摘 | Neilan B A Stuart J L Goodman A E | 1997 | Systematic and Applied Microbiology1997，20，： | 1 |
| 10 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet2001，，9286： | 1 |
| 11 | Oxford meniscal bearing knee versus the Marmor knee in unicompartmental arthroplasty for arthrosis显示文摘 | Stefan Lewold Stuart Goodman Kaj Knutson Otto Robertson Lars Lidgren | 1995 | The Journal of Arthroplasty1995，，6： | 1 |
| 12 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet2001，，9286： | 1 |
| 13 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet2001，，9286： | 1 |
| 14 | Specific amplification and restriction polymorphisms of the cyanobacterial rRNA operon spacer re-gion显示文摘 | Neilan B A Stuart J L Goodman A E | 1997 | Systematic and Applied Microbiology1997，20，4： | 1 |
| 15 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet2001，，9286： | 1 |
| 16 | Wear Particles,Periprosthetic Osteolysis and the Immune System显示文摘 | Goodman Stuart B | 2007 | Biomaterials2007，28，34： | 1 |
| 17 | COX-2 selective NSAID decreases bone ingrowth in vivo显示文摘 | Stuart Goodman Ting Ma Michael Trindade Takashi Ikenoue Ippe Matsuura Neal Wong Nora Fox Mark Genovese Don Regula R.Lane Smith | 2002 | Journal of Orthopaedic Research2002，，6： | 1 |
| 18 | Complications of ilioschial reconstruction rings in revision total hip arthroplaety显示文摘 | Stuart Goodman Hillary S Nadav S | 2004 | J Arthrop2004，19，4： | 1 |
| 19 | Modulating osteogenesis of mesenchymal stem cells by modifying growth factor availability显示文摘 | Zhinong Huang Pei-Gen Ren Ting Ma R. Lane Smith Stuart B. Goodman | 2010 | Cytokine2010，，3： | 1 |
| 20 | Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial显示文摘 | Michael P Manns John G McHutchison Stuart C Gordon Vinod K Rustgi Mitchell Shiffman Robert Reindollar Zachary D Goodman Kenneth Koury Mei-Hsiu Ling Janice K Albrecht | 2001 | The Lancet2001，，9286： | 1 |
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