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| 1 | 肛裂临床诊治指南(第三次修订)显示文摘“美国结直肠外科医师协会(American Societyof ColonandRectal Surgeons.ASCRS)”(协会)致力于推进结直肠和肛门疾病的相关理论以及预防和诊疗水平的提高,给患者提供优质的医疗服务。“标准委员会”由协会中在结直肠外科方面有显著专长的成员组成。该委员会的建立是为了引领国际结直肠和肛门疾病诊治的发展,以建立具有循证医学证据的临床诊疗指南。指南是涵盖性的,非指令性的,目的是为临床决策提供信息,而非具体的治疗方法。指南适用于所有相关的医护人员以及希望得到相应指南中疾病的相关诊治信息的患者。 | Farshid Araghizadeh ~ Robin Boushey Sridhar Chalasani George Chang Robert Cima Gary Dunn Daniel Feingold Philip Fleshner Daniel Geisler Jill Genua Sharon Gregorcyk Daniel Herzig Andreas Kaiser Ravin Kumar David Larson Steven Mills John Monson P. Terry Phang Feza Remzi David Rivadeneira Howard Ross Peter Senatore Elin Sigurdson Thomas Stahl Scott Steele Scott Strong Charles Tement Judith Trudel Madhulika Varnna Martin Weiser 丁义江(译) 皇甫少华(译) 丁曙晴(译) | 2013 | 中华胃肠外科杂志2013，16，7： | 70 |
| 2 | Increased function of the TRPV1 channel in small sensory neurons after local inflammation or in vitro exposure to the pro-inflammatory cytokine GRO/KC显示文摘Objective Inflammation at the level of the sensory dorsal root ganglia (DRGs) leads to robust mechanical pain behavior and the local inflammation has direct excitatory effects on sensory neurons including small, primarily nociceptive, neurons. These neurons express the transient receptor potential vanilloid-1 (TRPV1) channel, which integrates multiple signals of pain and inflammation. The aim of this study was to characterize the regulation of the TRPV1 channel by local DRG inflammation and by growth-related oncogene (GRO/KC, systemic name: CXCL1), a cytokine known to be upregulated in inflamed DRGs. Methods Activation of the TRPV1 receptor with capsaicin was studied with patch clamp methods in acutely isolated small-diameter rat sensory neurons in primary culture. In vivo, behavioral effects of TRPV1 and GRO/KC were examined by paw injections. Results Neurons isolated from lumbar DRGs 3 days after local inflammation showed enhanced TRPV1 function: tachyphylaxis (the decline in response to repeated applications of capsaicin) was significantly reduced. A similar effect on tachyphylaxis was observed in neurons pre-treated for 4 h in vitro with GRO/KC. This effect was blocked by H-89, a protein kinase A inhibitor. Consistent with the in vitro results, in vivo behavioral responses to paw injection of capsaicin were enhanced and prolonged by pre-injecting the paw with GRO/KC 4 h before the capsaicin injection. GRO/KC paw injections alone did not elicit pain behaviors. Conclusion Function of the TRPV1 channel is enhanced by DRG inflammation and these effects are preserved in vitro during short-term culture. The effects (decreased tachyphylaxis) are mimicked by incubation with GRO/KC, which has previously been found to be strongly upregulated in this and other pain models. | Fei Dong Yi-Ru Du Wenrui Xie Judith A. Strong Xi-Jing He Jun-Ming Zhang | 2012 | Neuroscience Bulletin2012，28，2： | 9 |
| 3 | Recent evidence for activity-dependent initiation of sympathetic sprouting and neuropathic pain显示文摘Traumatic injury or inflammatory irritation of the peripheral nervous system often leads to persistent pathophysiological pain states.It has been well-documented that,after peripheral nerve injury or inflammation,functional and anatomical alterations sweep over the entire peripheral nervous system including the peripheral nerve endings,the injured or inflamed afferent fibers,the dorsal root ganglion(DRG),and the central afferent terminals in the spinal cord.Among all the changes,ectopic discharge or spontaneous activity of primary sensory neurons is of great clinical interest,as such discharges doubtless contribute to the develop-ment of pathological pain states such as neuropathic pain.Two key sources of abnormal spontaneous activity have been identified following peripheral nerve injury:the injured afferent fibers(neuroma) leading to the DRG,and the DRG somata.The purpose of this review is to provide a global account of the abnormal spontaneous activity in various animal models of pain.Particular attention is focused on the consequence of peripheral nerve injury and localized inflammation.Further,mechanisms involved in the generation of spontaneous activity are also reviewed;evidence of spontaneous activity in contributing to abnormal sympathetic sprouting in the axotomized DRG and to the initiation of neuropathic pain based on new findings from our research group are discussed.An improved understanding of the causes of spontaneous activity and the origins of neuropathic pain should facilitate the development of novel strategies for effective treatment of pathological pain. | Jun-Ming ZHANG Judith A. Strong | 2008 | 生理学报2008，60，5： | 9 |
| 4 | Endothelium-specific gene and stem cell-based therapy for erectile dysfunction显示文摘可勃起的机能障碍(编辑) 通常源于全身的脉管系统的内皮机能障碍。尽管磷酸二酯酶打 5,(PDE-5 ) 禁止者在对待编辑的大多数盒子是有效的,他们必须习惯性地被带并且为人的一个有意义的数字是徒劳的。在最近的年基因和茎,目标为阴茎内皮细胞层的基于房间的治疗在现出症状之前的潜的研究一直在获得动量。这些早研究揭示基于房间的治疗可以是的那基因和茎不朽并且有效,并且可以最后为下列评论将加亮我们基于房间的治疗在很多个实验动物模型执行了到日期的 endothelial 特定的基因和茎的当前的理解的编辑导致痊愈。 | Travis D. Strong Milena A. Gebska Arthur L. Bumett Hunter C. Champion Trinity J. Bivalacqua | 2008 | Asian Journal of Andrology2008，10，1： | 8 |
| 5 | 肝移植治疗原发性胆汁性肝硬化的疗效分析显示文摘目的 观察原发性胆汁性肝硬化(PBC)患者和移植肝的实际生存时间,肝移植后死亡的原因及肝移植后的复发率。 方法 根据QLTS的数据库中的随访资料,回顾性分析52例共接受54次肝移植的PBC患者。52例PBC肝移植患者中,平均年龄(5 3.2±6.7)岁,平均随访时间是(5 5.4±11.3)个月。分析术前的临床特征、移植后生存情况和死亡原因,采用欧洲模式计算未接受肝移植患者和接受肝移植的患者的生存率。 结果 PBC肝移植患者的1、5、1 0年的实际生存率分别为8 8.4%、80.1%和76.9%,未接受肝移植患者实际生存率分别为80.9%、6 5.4%和19.8%。PBC患者移植后的生存率比未接受肝移植的患者(欧洲模型)预期生存率高。有6例患者经肝活检后证实PBC复发,平均复发时间(34.1±10.2)个月。肝移植术后死亡的原因是多器官功能衰竭、腹腔内出血、肾功能衰竭、败血症及心血管疾病。 结论 肝移植可提高P B C患者的生存率,延长其生存时间。 | 许崇恩 Stephen V.Lynch Glenda A.Balderson Jonathan Fawcett Russell W Strong Shinn Yeong | 2004 | 中华肝脏病杂志2004，12，9： | 6 |
| 6 | Inflammatory Changes in Paravertebral Sympathetic Ganglia in Two Rat Pain Models显示文摘Injury to peripheral nerves can lead to neuropathic pain, along with well-studied effects on sensory neurons, including hyperexcitability, abnormal spontaneous activity, and neuroinflammation in the sensory ganglia. Neuropathic pain can be enhanced by sympathetic activity. Peripheral nerve injury may also damage sympathetic axons or expose them to an inflammatory environment. In this study, we examined the lumbar sympathetic ganglion responses to two rat pain models: ligation of the L5 spinal nerve, and local inflammation of the L5 dorsal root ganglion(DRG), which does not involve axotomy.Both models resulted in neuroinflammatory changes in the sympathetic ganglia, as indicated by macrophage responses, satellite glia activation, and increased numbers of T cells, along with very modest increases in sympathetic neuron excitability(but not spontaneous activity) measured in ex vivo recordings. The spinal nerve ligation model generally caused larger responses than DRG inflammation.Plasticity of the sympathetic system should be recognized in studies of sympathetic effects on pain. | Ai-Ling Li Jing-Dong Zhang Wenrui Xie Judith A. Strong Jun-Ming Zhang | 2018 | Neuroscience Bulletin2018，34，1： | 6 |
| 7 | Is Gastric Cancer Different in Korea and the United States? Impact of Tumor Location on Prognosis显示文摘 | Jung Ho Shim Kyo Young Song Hae Myung Jeon Cho Hyun Park Lindsay M. Jacks Mithat Gonen Manish A. Shah Murray F. Brennan Daniel G. Coit Vivian E. Strong | 2014 | Annals of Surgical Oncology2014，，7： | 3 |
| 8 | Comparison of Gastric Cancer Survival Following R0 Resection in the United States and Korea Using an Internationally Validated Nomogram显示文摘 | Vivian E. Strong Kyo Young Song Cho Hyun Park Lindsay M. Jacks Mithat Gonen Manish Shah Daniel G. Coit Murray F. Brennan | 2010 | Annals of Surgery2010，，4： | 3 |
| 9 | Status, prediction and prevention of introduced cordgrass Spartina spp. invasions in Pacific estuaries, USA显示文摘 | Curtis C. Daehler Donald R. Strong | 1996 | Biological Conservation1996，，1： | 2 |
| 10 | Positive Peritoneal Cytology in Patients with Gastric Cancer: Natural History and Outcome of 291 Patients显示文摘 | James J. Mezhir MD Manish A. Shah MD Lindsay M. Jacks MS Murray F. Brennan MD Daniel G. Coit MD Vivian E. Strong MD | 2010 | Annals of Surgical Oncology2010，，12： | 2 |
| 11 | Changes in soil organic matter with cropping as measured by organic carbon fractions and 13C natural isotope abundance显示文摘 | Rod D. B. Lefroy Graeme J. Blair Wayne M. Strong | 1993 | Plant and Soil1993，，1： | 2 |
| 12 | Smoking is associated with advanced coronary atherosclerosis in youth显示文摘 | Arthur W. Zieske C. Alex McMahan Henry C. McGill Satoki Homma Hidehiro Takei Gray T. Malcom Richard E. Tracy Jack P. Strong | 2004 | Atherosclerosis2004，，1： | 2 |
| 13 | Evaluating the Environmental Health Effect of Bamboo-Derived Volatile Organic Compounds through Analysis the Metabolic Indices of the Disorder Animal Model显示文摘Objective To identify the bamboo VOCs(volatile organic compounds) effect on animal physiological indices, which associated with human health. Methods GC/MS was used to analyze the volatile organic compounds from Moso bamboo(Phyllostachys heterocyla cv. pubescens). The effect of VOCs on environmental health was evaluated by analyzing the metabolic indices of the type 2 diabetic mouse model. Results Spectra of VOC generated by GC/MS were blasted against an in-house MS library confirming the identification of 33 major components that were manually validated. The relative constituent compounds as a percentage of total VOCs determined were alcohols(34.63%), followed by ether(22.02%), aldehyde(15.84%), ketone(11.47%), ester(4.98%), terpenoid(4.38%), and acids(3.83%). Further experimentation established that the metabolic incidence of the disease can be improved if treated with vanillin, leaf alcohol, β-ionone and methyl salicylate. The effects of these VOCs on type 2 diabetes were evident in the blood lipid and blood glucose levels. Conclusion Our model suggests that VOCs can potentially control the metabolic indices in type 2 diabetes mice. This experiment data also provides the scientific basis for the comprehensive utilization of ornamental bamboos and some reference for other similar study of environmental plants. | GUO Ming HU Zheng Qing STRONG P.James SMIT Anne-Marie XU Jian Wei FAN Jun WANG Hai Long | 2015 | Biomedical and Environmental Sciences2015，28，8： | 2 |
| 14 | Neuromuscular electrical stimulation and the treatment of lower urinary tract dysfunction in multiple sclerosis— A double blind, placebo controlled, randomised clinical trial显示文摘 | D.McClurg R.G.Ashe A.S.Lowe‐Strong | 2008 | Urodyn2008，，3： | 2 |
| 15 | Minimally invasive surgery for gastric cancer显示文摘 | Zubin M. Bamboat Vivian E. Strong | 2012 | J Surg Oncol2012，，3： | 2 |
| 16 | Further studies on Diamond Growth Rates and Physical Properties of Laboratory made Diamond显示文摘 | Strong H M Chrenko R M | 1971 | J Phys Chem1971，75，： | 1 |
| 17 | Preventing stroke: saving lives around the world显示文摘 | Strong K Mathers C Bonita R | 2007 | Lancet Neurol2007，6，1： | 1 |
| 18 | Man-made diamonds显示文摘 | Bundy F P Hall H T Strong H M | 1955 | Nature1955，176，： | 1 |
| 19 | Early exclusive use of the affected forelimb after moderate transient focal ischemia in rats: functional and anatomic outcome显示文摘 | Bland ST Schallert T Strong R | 2000 | Stroke2000，31，5： | 1 |
| 20 | Ore deposits models-5: A model for granophile mineral deposits显示文摘 | Strong D F | 1981 | Geoscience Canada1981，8，4： | 1 |
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