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240篇 您的检索式：作者名="Stickel"

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	题名	作者	年代	出处	被引量
1	Increased liver stiffness in alcoholic liver disease:Differentiating fibrosis from steatohepatitis显示文摘AIM:To test if inflammation also interferes with liver stiffness (LS) assessment in alcoholic liver disease (ALD) and to provide a clinical algorithm for reliable fibrosis assessment in ALD by FibroScan (FS).METHODS:We first performed sequential LS analysis before and after normalization of serum transaminases in a learning cohort of 50 patients with ALD admitted for alcohol detoxification. LS decreased in almost all patients within a mean observation interval of 5.3 d. Six patients (12%) would have been misdiagnosed with F3and F4 fibrosis but LS decreased below critical cut-off values of 8 and 12.5 kPa after normalization of trans-aminases. RESULTS:Of the serum transaminases,the decrease in LS correlated best with the decrease in glutamic oxaloacetic transaminase (GOT). No significant chang-es in LS were observed below GOT levels of 100 U/L. After establishing the association between LS and GOT levels,we applied the rule of GOT < 100 U/L for reliable LS assessment in a second validation cohort of 101 patients with histologically confi rmed ALD. By ex-cluding those patients with GOT > 100 U/L at the time of LS assessment from this cohort,the area under the receiver operating characteristic (AUROC) for cirrhosis detection by FS improved from 0.921 to 0.945 while specificity increased from 80% to 90% at a sensitivity of 96%. A similar AUROC could be obtained for lower F3 fibrosis stage if LS measurements were restricted to patients with GOT < 50 U/L. Histological grading of inflammation did not further improve the diagnostic accuracy of LS.CONCLUSION:Coexisting steatohepatitis markedly increases LS in patients with ALD independent of fibrosis stage. Postponing cirrhosis assessment by FS during alcohol withdrawal until GOT decreases to < 100 U/mL signif icantly improves the diagnostic accuracy.	Sebastian Mueller Gunda Millonig Lucie Sarovska Stefanie Friedrich Frank M Reimann Maria Pritsch Silke Eisele Felix Stickel Thomas Longerich Peter Schirmacher Helmut Karl Seitz	2010	World Journal of Gastroenterology2010，16，8：	10
2	Carbide refining heat treatments for 52100 bearing steel显示文摘	C. A. Stickels	1974	Metallurgical Transactions1974，，4：	2
3	Fermented Noniexudate (fNE): a mediator between immune system and anti-tumor activity 显示文摘	Li J Stickel SL Bouton-Verville H etal	2008	Oncol Rep2008，20，6：	1
4	Cardiac safety of pegylated liposomal doxorubicin (PLD) in combination with trastuzumab (T) in patients with metastatic breast cancer (MBC) : results from a muhicenter phase Ⅱ study 显示文摘	Stickeler E Watermann DO Woll J	2007	J Clin Oncol 2007 ASCO Meeting Proceedings Part 12007，25，18：	1
5	Evidence that Volume Sustains Stock Price Changes显示文摘	STICKEL S E VERRECCHIA R E	1994	Financial Analyst Journal1994，50，6：	1
6	Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice显示文摘	Fanli Meng Kai Wang Tomonori Aoyama Sergei I. Grivennikov YongHan Paik David Scholten Min Cong Keiko Iwaisako Xiao Liu Mingjun Zhang Christoph H. ?sterreicher Felix Stickel Klaus Ley David A. Brenner Tatiana Kisseleva	2012	Gastroenterology2012，，3：	1
7	Coxsackie and adenovi- rus receptor promotes adenocarcinoma cell survival and is expres- sionallyactivated after transition from preneoplastic precursor le- sions to invasive adenocarcinomas显示文摘	Bruning A Stickeler E Diederich D	2005	Clin Cancer Res2005，11，12：	1
8	The characterization of enzymatically amplified eukaryotic 16S-like rRNA-coding regions 显示文摘	MEDLIN L ELWOOD H J STICKEL S	1988	Gene1988，71，2：	1
9	Transketolase protein TKTL 1 overexpression : A potential biomarker and therapeutic target in breast cancer 显示文摘	Foldi M Stickeler E Bau L	2007	Oncol Rep2007，17，4：	1
10	Telecentric beam position for advanced E-beam lithography显示文摘	Stickel W Langner G O	1992	Microcircuit Eng1992，17，4：	1
11	Fermented Noni exudate (t'NE): a mediator between immune system and anti-tumor activity显示文摘	LI J STICKEL SL BOUTON-VERVILLE H	2008	Oncol Rep2008，20，6：	1
12	Inhibition of Integrin αvβ6 on Cholangiocytes Blocks Transforming Growth Factor-β Activation and Retards Biliary Fibrosis Progression显示文摘	Eleonora Patsenker Yury Popov Felix Stickel Alfred Jonczyk Simon L. Goodman Detlef Schuppan	2008	Gastroenterology2008，，2：	1
13	Fermented Noni exudate(fNE):a mediator between immune system and anti-tumor activity显示文摘	LI J STICKEL S L BOUTON-VERVILLE H	2008	Oncol Rep2008，20，6：	1
14	Herbal medicine in the treatment of liver diseases显示文摘	Stickel F Schuppan D	2007	Dig Liver Dis2007，39，4：	1
15	Weak expression of focal adhesion kinase (pp125FAK) in patients with cervical cancer is associated with poor disease outcome 显示文摘	Gabriel B zur Hausen A Stickeler E	2006	Clln Cancer Res2006，12，8：	1
16	Reputation and performance among security analysts显示文摘	Stickel S	1992	Journal of Finance1992，47，5：	1
17	Fermented Noni exudate(f NE):a mediator between immune system and anti-tumor activity显示文摘	Li J Stickel SL Bouton-Verville H	2008	Oncol Rep2008，20，6：	1
18	Inhibition of integrin alpha-beta on cholangiocytes blocks transforming growth factor-beta activation and re-tards biliary fibrosis progression 显示文摘	Patsenker E Popov Y Stickel F	2008	Gastroenterology2008，135，3：	1
19	Intron 9 retention in gene transcripts suggests involvement of CD44 in the tumorigenesis of ovarian cancer 显示文摘	Kieback D G Stickeler E Mobus V J	2004	Anticancer Res2004，37，6：	1
20	Alcoholic liver disease from pathophysiology to therapy 显示文摘	Seitz HK Lieber CS Stickel F	2005	Alcohol Clin Exp Res2005，29，7：	1

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