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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study显示文摘 | Pierre Fenaux Ghulam J Mufti Eva Hellstrom-Lindberg Valeria Santini Carlo Finelli Aristoteles Giagounidis Robert Schoch Norbert Gattermann Guillermo Sanz Alan List Steven D Gore John F Seymour John M Bennett John Byrd Jay Backstrom Linda Zimmerman David M | 2009 | Lancet Oncology2009，，： | 2 |
| 3 | Reoperation for prosthetic aortic valve obstruction in the era of echocardiography: trends in diagnostic testing and comparison with surgical findings显示文摘 | Steven E Girard Fletcher A Miller Thomas A Orszulak Charles J Mullany Samantha Montgomery William D Edwards Henry D Tazelaar Joseph F Malouf A.Jamil Tajik | 2001 | Journal of the American College of Cardiology2001，，2： | 2 |
| 4 | Apparent digestibility of gross nutrients from feedstuffs in extruded feeds for rainbow trout (Oncorhynchus mykiss ) 显示文摘 | GAYLORD T G BARROWS F T STEVEN D R | 2008 | Journal of the World Aquaculture Society2008，39，6： | 1 |
| 5 | C-Methyl-flavonoids from the leaf waxes of some Myrtaceae显示文摘 | Eckhard Wollenweber Rüdiger Wehde Marion D?rr Günter Lang Jan F Stevens | 2000 | Phytochemistry2000，，8： | 1 |
| 6 | Contour integration in the peripheral field显示文摘 | Hess R F Steven C D | 1999 | Vision Research1999，39，5： | 1 |
| 7 | Cancellation of GLONASS signals from radio astronomy da- ta 显示文摘 | ELLINGSON Steven W BUNTON John D BELL Jon F | 2009 | The Smithsonian/NASA Astrophysics Data System2009，4015，： | 1 |
| 8 | Interpersonal Aggression and the Type A Coronary-Prone Behavior Pattern:A Theoretical Distinction and Practical Implications显示文摘 | Strube M J Turner D W Cerro D Stevens J & Hinchey F | 1984 | Journal of Personality and Social Psychology1984，47，： | 1 |
| 9 | Temozolomide:mechanisms of action,repair and resistance显示文摘 | Zhang J Stevens M F Bradshaw T D | 2012 | Curr Mol Pharmacol2012，5，1： | 1 |
| 10 | High spectral resolution data for determining leaf water content 显示文摘 | F M Danson M D Steven T J Malthus | 1992 | International Journal of Remote Sensing1992，13，3： | 1 |
| 11 | Effect of stacking sequence on micro-cracking in a cryogenically cycled carbon/ bismaleimide composite 显示文摘 | Bethel V T Mark B F Steven L D | 2003 | Composites: Part A2003，34，7： | 1 |
| 12 | The Aerodynamics of free- flight maneuvers in drosophila 显示文摘 | Steven N F Rosalyn S Michael H D | 2003 | Science2003，300，： | 1 |
| 13 | Avian and hu-man receptor binding by hemagglutinins of influenza A viruses显示文摘 | Russell R J Stevens D J HaireL F | | 0，，： | 1 |
| 14 | Complication: Neuropathy, Pathogenetic considerations 显示文摘 | Sima A A F Stevens M J | 1992 | Diabetes Care1992，15，： | 1 |
| 15 | In- tercalibration of vegetation indices from different sensor systems显示文摘 | STEVEN M D MALTHUS T J BARET F | 2003 | Remote Sensing of Environment2003，88，4： | 1 |
| 16 | ptimization of soil-adjusted vegetation indices显示文摘 | Rondeaux G Steven M D Baret F | 1996 | Remote Sensing of Environment1996，55，： | 1 |
| 17 | The distribution and retention of hexavalent 233U in the beagle显示文摘 | Stevens W Bruenger F W Atherton D R | | 0，，01： | 1 |
| 18 | Decomposition of myceliar matrix and extraction of chitosan from Gongronella butlerl USDB 0201 and Absidia coeruleareak ATCC 14076显示文摘 | Nwe N Stevens W F Montet D | 2008 | Internation- al Journal of Biological Macromolecules2008，43，1： | 1 |
| 19 | Crystal size distribution in continuous crystallizer when growth rate is size-dependent 显示文摘 | Abegg C F Stevens J D Larson M A | 1968 | AIChE J1968，14，： | 1 |
| 20 | The regiospecific synthesis of 5-and 7-monosubstituted and 5,6-disubstituted 2-arylbenzothiazoles显示文摘 | Hutchinson I Stevens M F G Westwell A D | 2000 | Tetrahedron Lett2000，41，3： | 1 |
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