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| 1 | Encapsulating peritoneal sclerosis显示文摘Encapsulating peritoneal sclerosis(EPS) is a debilitating condition characterized by a fibrocollagenous membrane encasing the small intestine, resulting in recurrent small bowel obstructions. EPS is most commonly associated with long-term peritoneal dialysis, though medications, peritoneal infection, and systemic inflammatory disorders have been implicated. Many cases remain idiopathic. Diagnosis is often delayed given the rarity of the disorder combined with non-specific symptoms and laboratory findings. Although cross-sectional imaging with computed tomography of the abdomen can be suggestive of the disorder, many patients undergo exploratory laparotomy for diagnosis. Mortality approaches 50% one year after diagnosis. Treatment for EPS involves treating the underlying condition or eliminating possible inciting agents(i.e. peritoneal dialysis, medications, infections) and nutritional support, frequently with total parenteral nutrition. EPSspecific treatment depends on the disease stage. In the inflammatory stage, corticosteroids are the treatment of choice, while in the fibrotic stage, tamoxifen may be beneficial. In practice, distinguishing between stages may be difficult and both may be used. Surgical intervention, consisting of peritonectomy and enterolysis, is timeconsuming and high-risk and is reserved for situations in which conservative medical therapy fails in institutions with surgical expertise in this area. Herein we review the available literature of the etiology, pathogenesis, diagnosis, and treatment of this rare, but potentially devastating disease. | Christopher J Danford Steven C Lin Martin P Smith Jacqueline L Wolf | 2018 | World Journal of Gastroenterology2018，24，28： | 13 |
| 2 | N-acetylcysteine treats intravenous amiodarone induced liver injury显示文摘We report a case of intravenous(IV) amiodarone drug induced liver injury(DILI).The patient received IV N-acetylcysteine(NAC) which resulted in a rapid improvement in liver enzymes.While the specific mechanisms for the pathogenesis of IV amiodaroneDILI and the therapeutic action of IV NAC are both unknown, this case strongly implies at least some commonality.Because IV amiodarone is indicated for the treatment of serious cardiac arrhythmias in an intensive care unit setting, some degree of ischemic hepatitis is likely a cofactor in most cases. | Matthew L Mudalel Kartikeya P Dave James P Hummel Steven F Solga | 2015 | World Journal of Gastroenterology2015，21，9： | 5 |
| 3 | 生物素——抗结核药物新研究方向(英文)显示文摘耐药菌的出现对全球公共卫生构成了巨大的挑战,结核分枝杆菌(TB)是结核病的病原菌,是临床上最重要的病原体之一。新抗生素的研发用以治疗耐药性结核病已成为临床及公共卫生管理亟待解决的重要问题。生物素(维生素B7)在结核杆菌的代谢途径如脂肪酸合成和三羧酸循环中发挥重要作用,通过生物素蛋白连接酶连接活性辅助因子而被激活。生物素蛋白连接酶及其相关生物合成通路是微生物合成生物素过程中必不可或缺的关键分子,因而有可能成为新的药物靶点。遗传研究表明,结核杆菌需要由菌体进行生物素的全程合成,因此,生物素合成酶在在结核杆菌代谢过程中起着至关重要的作用,引起了抗结核药物研究者的高度重视。本文论述了结核杆菌生物素合成通路,并重点分析了生物素合成过程中可能成为药物靶点的关键酶,旨在为结核病的治疗提供新思路,具有重要的临床意义。 | THOMPSON Andrew P STERNICKI Louise M WEGENER Kate L 陆伟 竺丽梅 BOOKER Grant W POLYAK Steven W 李燕 | 2016 | 江苏预防医学2016，27，3： | 4 |
| 4 | Decay estimates for fourth order wave equations显示文摘 | Steven P L | 1998 | Journal of Differential Equations1998，143，： | 2 |
| 5 | Stability and instability of fourth-order solitary waves 显示文摘 | Steven P L | 1998 | Jottmal of Dynamics and Differential Equations1998，10，1： | 2 |
| 6 | Phenotypic instability and rapid gene silencing in newly formed Arabidopsis alloteraploids显示文摘 | Comai L Tyagi A P Winter K Holmes-Davis R Reynolds S H Stevens Y Byers B | 2000 | Plant Cell2000，12，9： | 2 |
| 7 | Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias显示文摘 | Steven L Higgins John D Hummel Imran K Niazi Michael C Giudici Seth J Worley Leslie A Saxon John P Boehmer Michael B Higginbotham Teresa De Marco Elyse Foster Patrick G Yong | 2003 | Journal of the American College of Cardiology2003，，8： | 2 |
| 8 | Vibration-Based model-dependent damage (delamination) identification and health monitoring for composite structures-a review 显示文摘 | Zou Y Tong L Steven G P | 2000 | Journal of Sound and vibration2000，230，2： | 1 |
| 9 | Vibration-based model-dependent damage (delamination) identification and health monitoring tor composite structures-a review 显示文摘 | Zou Y Tong L Steven G P | 2000 | Journal of Sound and Vibration2000，230，2： | 1 |
| 10 | Symbolic or substantive document? The influence of ethics codes on financial executives' decisions显示文摘 | Stevens J M Steensma H K Harrison D A Cochran P L | | 0，，2： | 1 |
| 11 | Micromechanics models for mechanicaland thermomechanical properties of 3D through-thethicknessangle interlock woven composites 显示文摘 | TAN P T L STEVEN G P | 1999 | CompositesPart A:Applied Science and Manufacturing1999，30，： | 1 |
| 12 | Effects of spirodiclofenon reproduction in a susceptible and resistant strain of tetranychusurticae显示文摘 | Steven V P Jahanqir K Thomas V L | 2009 | Experimental & AppliedAcarology2009，47，： | 1 |
| 13 | Modeling for predicting the mechanical properties of textile composites-a review显示文摘 | TAN P TONG L & STEVEN G P | 1997 | Composites:Part A1997，28，： | 1 |
| 14 | Modeling approaches for 3Dorthogonal woven composites显示文摘 | Tan P L Tong GP Steven | 1998 | Journal of Reinforced Plastics and Composites1998，17，6： | 1 |
| 15 | Characterization of isomeric sulfonamides using capilary zone exlectrophoresis coupled with nano-electrospray quasi-MS-MS-MS显示文摘 | Kevin P B Steven J L Dietrich A V | 1997 | J Mass Spectrom1997，，32： | 1 |
| 16 | Analysis of high-dispersion tracer tests in cores containing polymer gels显示文摘 | Aniello M Steven L B Thomas P L | 1999 | Journal of Petrole-um Science and Engineering1999，，23： | 1 |
| 17 | Piezoelectric Actuator Orientation Optimization for Static Shape Control of Composite Plates 显示文摘 | CHEE C TONG L STEVEN G P | 2002 | Composite Structures2002，55，： | 1 |
| 18 | VEGF induces Mcl-1 up-regulation and protects multiple my-eloma cells against apoptosis显示文摘 | STEVEN L G KLAUS P MARTINE A | 2004 | Blood2004，104，9： | 1 |
| 19 | A practical twostep quantitative clinical and ehetrophysiologieal assessment for the diagnosis and staging of diabetle neuropathy 显示文摘 | Feldman E L Stevens M J Thomas P K | 1994 | Diabetes Care1994，17，11： | 1 |
| 20 | A flexible datapath allocation method for architectural synthesis显示文摘 | Kyumyung C Steven P L | 1999 | ACM Transactions on Design Automation of Electronic Systems1999，4，4： | 1 |
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