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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | 中国3-18岁儿童青少年骨密度参照标准:2013-2015年中国儿童青少年心血管健康研究横断面结果显示文摘目的骨骼是构成人体的支架,是儿童青少年正常生长发育的基础。人体骨量在20岁左右达到峰值,骨峰值的80%在青少年时期形成。研究证明,峰值骨量决定了中老年的骨量丢失和发生骨质疏松的风险。正确评价儿童的骨密度对于评价正常儿童的生长发育,发现偏移、运动不足及营养相关导致的骨量不足以及继发性(原发病引起和药物引起)骨质疏松具有重要意义。目前,中国没有基于全国数据的儿童青少年骨密度参照标准,本研究旨在建立中国3~18岁儿童青少年骨密度参照值。方法数据来源于2013—2015年中国儿童青少年心血管健康横断面研究,采用双能x线(dualenergyx-ra,absorptiometry,DXA)骨密度仪对7省、自治区、直辖市的10818名3-18岁儿童青少年进行了骨密度检测。采用LMS曲线平滑技术对年龄别傍高别骨密度百分位曲线进行平滑,得出中国3~18岁儿童青少年年龄别/身高别骨密度参照标准。结果东北地区的吉林省儿童青少年平均去头骨密度(totalbodylessheadbonemineraldensity,TBLHBMD)最高,华东地区山东省儿童最低。TBLHBMD随着年龄和身高的增长而增加,男童的TBLHBMD高于女童。与美国儿童TBLHBMD对比发现,不论年龄别、身高别TBLHBMD,美国儿童在每个百分位均高于中国儿童;中美两国儿童身高别TBLHBMD存在很大差异,美国儿童显著高于中国儿童,其中中位数和第3百分位差距最大。结论本研究建立的标准是首个基于中国3-18岁儿童青少年的大样本、广地域人群的骨密度参照标准。以TBLHBMD低于平均水平0~1倍标准差(相当于第51百分位~第15.9百分位)和1~2倍标准差(相当于第15.8百分位~第2.3百分位)作为骨量发育不足和骨量发育严重不足的评价标准,不足者可通过生活方式和饮食干预;以低于2倍标准差(相当于低于第2.2百分位)作为骨量发育异常的评价标准,骨量发育异常者需结合临床进行干预。 | 刘军廷 王亮 孙景辉 刘功姝 严卫丽 席波 熊丰 丁文清 黄费民 Steven Heymsfield 米杰 | 2017 | 英国医学杂志中文版2017，20，9： | 10 |
| 3 | Skeletal Muscle Mass and Distribution in 468? Men and Women Aged 18-88 yr显示文摘 | IAN JANSSEN STEVEN B HEYMSFIELD ZIMIAN WANG | 2000 | Appl Physiol2000，89，： | 1 |
| 4 | Body mass index versus percentage body fat in Chinese, African-American and Caucasian postmenopausal women显示文摘Objective: The aim of the study was to investigate in postmenopausal women whether the relationship between percentage body fat (PBF) and body mass index (BMI) differs between Asians living in Beijing (BA) and African-Americans (AA), and Caucasians (Ca) living in New York City. Methods: Healthy postmenopausal women (231 BA; 113 AA, 95 Ca), aged 50-80 years, were studied. Weight, height and PBF by dual energy X-ray absorptiometry (DXA) were measured. The relationship between PBF and BMI was assessed by multiple regression analysis. Results: Race, reciprocal of BMI (1/BMI) and the interaction between race and 1/BMI were all significantly (P<0.05) related to PBF in this sample. The slope of the line relating 1/BMI to PBF was different for BA compared to AA (P=0.01) and Ca (P=0.003) while the slopes for AA and Ca were not different (P>0.05). At lower levels of BMI, Asians tended to have higher PBF comparable to AA and Ca, while at BMI >30 BA tended to have less PBF than the other groups. Conclusion: The relation between PBF and BMI in BA postmenopausal women differs from that of AA and Ca women in this sample. | 孙爱军 何清 林守清 田均平 Stan He-shka Jack Wang Steven Heymsfield Richard N. Pierson Dympna Gallagher | 2006 | 生殖医学杂志2006，15，B10： | 1 |
| 5 | Race-ethnicity-specific waist circumference cutoffs for identifying cardiovascular disease risk factors显示文摘 | Shankuan Zhu Steven B Heymsfield Hideaki Toyoshima | 2005 | Am J Clin Nutr2005，81，： | 1 |
| 6 | Short Sleep Duration as a Risk Factor for Hypertension: Analyses of the First National Health and Nutrition Examination Survey显示文摘 | James E. Gangwisch Steven B. Heymsfield Bernadette Boden-Albala Ruud M. Buijs Felix Kreier Thomas G. Pickering Andrew G. Rundle Gary K. Zammit Dolores Malaspina | 2006 | Hypertension2006，，： | 1 |
| 7 | Urinary Creatinine-Skeletal Muscle Mass Method:A Prediction Equation Based on Computerized Axial Tomography显示文摘A classic body composition method is estimation of total body skeletal muscle mass (SM, kg) from 24 h urinary creatinine excretion (Cr, g). Two types of prediction equations were suggested: one assumes a constant SM/Cr ratio; and the other assumes a highly variable SM/Cr ratio. We explored these two extreme possibilities by measuring SM with whole-body computerized axial tomography and collecting Cr during meat-free dietary conditions in 12 healthy young men. Prediction equations were developed in the men that fit these two equation types, SM = 21.8×Cr (SD and CV of SM/Cr ratio, 1.3 kg and 6.0%,respectively) and SM = 18.9 × Cr + 4.1 (r = 0.92, p = 2.55 × 10-5, and SEE = 1.9 kg). The validity of each model is reviewed. This is the first investigation of Cr-SM method using modern techniques for quantifying total body SM | ZI-MIAN WANG YUN-GAO SUN AND STEVEN B. HEYMSFIELD (Department of Medicine, Obesity Research Center, St. Luke’s-Roosevelt Hospital, Columbia University College of Physicians and Surgeons,Amsterdam Ave. 14C New York, N. Y., USA)(Obesity Research Center, We | 1996 | Biomedical and Environmental Sciences1996，9，2： | 0 |
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