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| 1 | Medical training fails to prepare providers to care for patients with chronic hepatitis B infection显示文摘AIM: To investigate physicians' knowledge including chronic hepatitis B(CHB) diagnosis, screening, and management in various stages of their training.METHODS: A voluntary 20-question survey was administered in Santa Clara County, CA where Asian and Pacific Islanders(API) account for a third of the population. Among the 219 physician participants,there were 63 interns, 60 second-year residents, 26 chief residents and 70 attending physicians. The survey asked questions regarding respondents' demographics,general hepatitis B virus knowledge questions(i.e.,transmission, prevalence, diagnostic testing, prevention,and treatment options), as well as, self-reported practice behavior and confidence in knowledge.RESULTS: Knowledge about screening and managing patients with CHB was poor: only 24% identified the correct tests to screen for CHB, 13% knew the next steps for patients testing positive for CHB, 18% knew the high prevalence rate among API, and 31% knew how to screen for liver cancer. Wald chi-square analysis determined the effect of training level on knowledge; in all cases except for knowledge of liver cancer screening(p = 0.0032), knowledge did not significantly increase with length in residency training or completion of residency.CONCLUSION: Even in a high-risk region, both medical school and residency training have not adequatelyprepared physicians in the screening and management of CHB. | Stephanie D Chao Bing-Mei Wang Ellen T Chang Li Ma Samuel K So | 2015 | World Journal of Gastroenterology2015，21，22： | 2 |
| 2 | 【特刊综述】雄激素和前列腺疾病显示文摘越来越多的文献认同睾酮治疗在性腺机能低下患者中具有促合成代谢作用。而关于老年男性使用外源性雄激素的风险和其对前列腺潜在副作用的研究数据仍然匮乏。老年和性腺机能低下男性接受睾酮治疗是否会加重下尿路症状或加剧、揭露,甚至刺激前列腺癌发展,这一问题使采用睾酮治疗的热情有所减缓,与此同时前列腺疾病被视作睾酮治疗的相对禁忌。雄激素对于前列腺的发育和维护是必要的。无论如何,流行病学研究并没有一致地发现内源性血清雄激素浓度与前列腺疾病风险之间存在正相关。虽然最新研究显示5α还原酶抑制剂降低了患低级别前列腺癌的风险,说明抑制雄激素代谢有利于前列腺健康,但是对于高级别前列腺癌并没有类似作用,因此对这些药物化学预防的真正临床效益提出了质疑。鉴于缺乏大样本随机试验,很难了解如何最好地研究雄激素和前列腺疾病发展之间的关系。越来越多研究质疑雄激素在血清中的变化与其在前列腺激素环境中的变化有类似效应或者改变腺体内雄激素的调节过程。需要长期的干预性研究来真正证实雄激素对前列腺组织和疾病风险的操控。然而,现有数据认为恢复血清雄激素至生理水平并不会触发前列腺疾病。 | Lori A Cooper Stephanie T Page | 2014 | Asian Journal of Andrology2014，16，2： | 2 |
| 3 | Bacterial RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condition 显示文摘 | Paolo C Dave W Robert J B Don C A Jay H Martin S Mark A Ganesh K Sara S Robert D Santiago N Stephanie B Mary F Jayaprakash T Santanu D Christopher B Michael H L Jacqueline E H | 2008 | Plant Physiology2008，147，2： | 1 |
| 4 | Sex reassignment of adolescent transsexuals: a follow-up study显示文摘 | Peggy T Cohen-Kettenis PhD Stephanie HM | 1997 | Am Acad Child Adolesc Psychiatry1997，36，： | 1 |
| 5 | Fostering resilience to extreme events within infrastructure systems:characterizing decision contexts for mitigation and adaptution显示文摘 | McDaniels T Stephanie Chang Darren Cole | 2008 | Global Environmental Change2008，18，： | 1 |
| 6 | Quantificadon of coronary artery stenoses:comparison of 64-slice and dual source CT angiography with cardiac catheterization显示文摘 | Stephanie B Nikolaou K Johnson T | 2007 | Radiologe2007，47，4： | 1 |
| 7 | A foundermutation of the MSH2 gene and hereditary nonpolyposis eolorectal cancer in the United States显示文摘 | HENRY T LYNCH STEPHANIE M CORONEL ROSS OKIMOTO | 2004 | JAMA2004，291，6： | 1 |
| 8 | Metal -ion sensing fluorophores with large two - photon absorption cross sections: aza - crown ether substituted donor - acceptor - donor distyryjbenzenes 显示文摘 | Stephanie J K P Osamu T Maria C R | 2004 | J Am Chem Soc2004，126，： | 1 |
| 9 | Inhibition of vascularization in rabbit corneals by heparin, cortisone pellets显示文摘 | Linbisa N Jadith F Stephanie T | 1986 | Invest Ophthalmol Vis Sci1986，27，4： | 1 |
| 10 | Evaluation the reinforcing effects of choice in comparison to reinforcement rate 显示文摘 | Rachel H T Wayne W F Stephanie A C | 1998 | Research in Developmental Disabilities1998，19，2： | 1 |
| 11 | Evaluation the reinforcing effects of choice in comparison to reinforcement rate显示文摘 | Rachel H T Wayne W F Stephanie A C | 1998 | Research in Developmental Disabilities1998，19，2： | 1 |
| 12 | Plasma concentration of N-terminal pro-brain natriurtic peptide in control children from the neonatal to adolescent period and in children with congestive heart failure显示文摘 | Mir T Stephani S Eiselt M | 2002 | Pediatrics2002，110，6： | 1 |
| 13 | Modulating Estrogen Receptor-related Receptor-α Activity Inhibits Cell Proliferation 显示文摘 | Stephanie B Olivia L Violaine T | 2009 | Journal of Biological Chemistry2009，284，23： | 1 |
| 14 | Genetic diversity of canine olfactory receptors 显示文摘 | STEPHANIE R SANDRINE T MAUD R | 2009 | Brae Genomies2009，10，1： | 1 |
| 15 | Calpain inhibitors improve myocardial dysfunction and inflammation induced by endotoxin in rats显示文摘 | Stephanie T Steve L Xavier M | 2004 | Shock2004，21，4： | 1 |
| 16 | Quantificalion of coronary artery stenoses: comparison of 64-slice and dual source CT angiography with cardiac catheterization 显示文摘 | Stephanie B Nikolaou K Johnson T | 2007 | Radiologe2007，47，4： | 1 |
| 17 | Cytochrome P450 specifieities of alkoxyresorufin O-dealkylation in human and rat liver显示文摘 | Burke MD Stephanie T Clifford RE | 1994 | Bioehem Pharmaeol1994，48，5： | 1 |
| 18 | Black carbon emissions in China显示文摘 | STREETS D G SHALINI G STEPHANIE T | 2001 | Atmospheric Environment2001，35，： | 1 |
| 19 | Turf grass establishment on various root zones显示文摘 | James A M H iranthi S Josh A H Lawson T J Stephanie L M | 2004 | USGA Green Section Record2004，42，4： | 1 |
| 20 | Recognition and management of nonrelaxing pelvic floor dysfunction显示文摘 | Stephanie S Faubion Lynne T Shuster Adil E | 2012 | Clinic proceedings2012，87，2： | 1 |
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