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| 1 | Increased resistance of drought by Trichoderma harzianum fungal treatment correlates with increased secondary metabolites and proline content显示文摘Plant secondary metabolites play vital role in plant stress response. In this study we investigated whether root colonization of tomato(Solanum lycopersicum) infected by Trichoderma harzianum leads to alterations in the biosynthesis of secondary plant metabolites including phytohormones and osmolyte proline under drought stress. Exposure of tomato to drought caused a drastic decline in plant growth and physiological parameters. Tomato inoculated with T. harzianum showed increased root and shoot growth and chlorophyll pigments as compared to uninoculated controls as well as drought stressed plants. Proline and total soluble protein content was increased in plants inoculated with T. harzianum under both normal as well as drought conditions. An obvious increase in phenol and flavonoid content was observed due to T. harzianum. In addition, T. harzianum inoculated plants maintained higher levels of growth regulators indole acetic acid, indole butyric acid, and gibberellic acid under drought stress. Improved secondary metabolites which play an important role in plant stress tolerance by T. harzianum may have coordinately worked for bringing the growth regulation by protecting membranes from reactive oxygen species(ROS) and enhance plant growth through accessing more nutrients by root system. | Mona S.Alwhibi Abeer Hashem Elsayed Fathi Abd_Allah Abdulaziz A.Alqarawi Dina Wafi K.Soliman Stephan Wirth Dilfuza Egamberdieva | 2017 | Journal of Integrative Agriculture2017，16，8： | 15 |
| 2 | Microbial activity in a sandy arable soil is governed by the fertilization regime显示文摘 | Timo Kautz Stephan Wirth Frank Ellmer | 2004 | European Journal of Soil Biology2004，，2： | 2 |
| 3 | Short-Term Response of Soil Respiration to Addition of Chars:Impact of Fermentation Post-Processing and Mineral Nitrogen显示文摘The biodegradability of chars derived from pyrolysis and hydrothermal carbonisation(HTC) was studied in short-term dynamic incubation experiments under controlled conditions. Carbon dioxide C(CO2) emissions from soil-char mixtures in combination with solid digestate or mineral nitrogen(N) fertiliser were measured in dynamic chambers for 10 d. Compared to the original material(maize straw), pyrolysis and HTC chars showed significantly lower CO2 emissions and slower decay dynamics; and compared to the soil control, HTC char increased soil respiration to a significant extent, while pyrolysis char did not. The addition of mineral N resulted in a delayed respiration dynamics for HTC char, while the addition of digestate resulted in an increase in the respired CO2 for pyrolysis char and a decrease for HTC char. For the first time, a peculiar two-stage decay kinetics was observed for HTC char,indicating a highly inhomogeneous substrate consisting at least of two C pools. | Giacomo LANZA Stephan WIRTH Arthur GESSLER Jrgen KERN | 2015 | Pedosphere2015，25，5： | 2 |
| 4 | Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death显示文摘 | Alexander Seiler Manuela Schneider Heidi F?rster Stephan Roth Eva K. Wirth Carsten Culmsee Nikolaus Plesnila Elisabeth Kremmer Olof R?dmark Wolfgang Wurst Georg W. Bornkamm Ulrich Schweizer Marcus Conrad | 2008 | Cell Metabolism2008，，3： | 2 |
| 5 | Prevalence of autoantibodies and the risk of autoimmune thyroid disease in children with chronic hepatitis C virus infection treated with interferon-α显示文摘AIM: To evaluate the prevalence of autoantibodies in chronic hepatitis C virus (HCV)-infected children focusing on thyroid autoimmunity. METHODS: We investigated the prevalence of auto- antibodies in 123 chronic HCV-infected children before, during and after monotherapy with interferon-alpha (IFN-α) or combined treatment with interferon-α or peginterferon-α and ribavirin. Besides antibodies against smooth muscle (SMA), nuclei (ANA), and liver/kidney microsomes (LKM), the incidence of anti- thyroid peroxidase antibodies as well as thyroid function parameters (TSH, FT3 and FT4) were determined. RESULTS: We found that 8% of children had autoantibodies before treatment. During treatment, 18% of children were found positive for at least one autoantibody; 15.5% of children developed pathologic thyroid values during IFN-α treatment compared to only one child before therapy. Six children had to be substituted while developing laboratory signs of hypothyroidism. CONCLUSION: Our data indicate a strong correlation between interferon-α treatment and autoimmune phenomena, notably the emergence of thyroid antibodies. The fact that some children required hormone replacement underlines the need of close monitoring in particularly those who respond to therapy and have to be treated for more than 6 mo. | Stephan Gehring Ulrike Kullmer Sabine Koeppelmann Patrick Gerner Philip Wintermeyer Stefan Wirth | 2006 | World Journal of Gastroenterology2006，12，36： | 2 |
| 6 | Microbial activity in a sandy arable soil is governed by the fertilization regime显示文摘 | Timo Kautz Stephan Wirth Frank Ellmer | 2004 | European Journal of Soil Biology2004，40，： | 1 |
| 7 | Cellulose-Degrading Potentials and Phylogenetic Classification of Carboxymethyl-cellulose Decomposing Bacteria Isolated from Soil显示文摘 | Stephan Wirth Andreas Ulrich | | 0，，25： | 1 |
| 8 | Secondary salinity effects on soil microbial biomass显示文摘 | Dilfuza Egamberdieva Giancarlo Renella Stephan Wirth Rafiq Islam | 2010 | Biology and Fertility of Soils2010，，5： | 1 |
| 9 | Recombinant alfa-interferon plus ribavirin therapy in children and adolescents with chronic hepatitis C显示文摘 | Stefan Wirth Thomas Lang Stephan Gehring Patrick Gerner | 2002 | Hepatology2002，，5： | 1 |
| 10 | Prevalence of hepatitis B virus precore stop codon mutations in chronically infected children显示文摘瞄准:为了发现是否在 precore 站的流行有有效差量,在在积极的 HBeAg 和 anti-HBe 之间的变化上哄骗积极孩子。方法:我们调查了 155 个欧洲孩子的一张大小儿科的人口(意味着年龄 10.9 年) 与由 PCR 并且直接定序的长期的肝炎 B。90 是积极的 HBeAg 和 65 有的 seroconversion 到 anti-HBe。另外, genotyping 被执行。结果:(48%) 74 定序的 HBV 紧张被归因于遗传型 D 并且 81 (52%) 到遗传型 A。在 90 个 HBeAg 积极病人的组, 2 (2.2%) 变化上的 1896-G-to-A 转变导致 precore 站鳕鱼被发现,并且在 65 anti-HBe 的组积极孩子,(7.7%) 5 被识别 harbouring HBeAg 减异种。差别不是统计上重要的(P = 0.13 ) 。结论:减占优势的病毒的 HB 紧张在欧洲孩子在长期的肝炎 B 期间起一个次要的作用的变体的 HBeAg。 | Philip Wintermeyer Patrick Gerner Stephan Gehring Afshin Karimi Stefan Wirth | 2006 | World Journal of Gastroenterology2006，12，14： | 1 |
| 11 | Endophytic bacteria associated with halophyte Seidlitzia rosmarinus Ehrenb.ex Boiss.from saline soil of Uzbekistan and their plant beneficial traits显示文摘Endophytic bacteria of halophytic plants play essential roles in salt stress tolerance.Therefore,an understanding of the true nature of plant-microbe interactions under extreme conditions is essential.The current study aimed to identify cultivable endophytic bacteria associated with the roots and shoots of Seidlitzia rosmarinus Ehrenb.ex Boiss.grown in the salt-affected soil in Uzbekistan and to evaluate their plant beneficial traits related to plant growth stimulation and stress tolerance.Bacteria were isolated from the roots and the shoots of S.rosmarinus using culture-dependent techniques and identified by the 16S rRNA gene.RFLP(Restriction Fragment Length Polymorphism)analysis was conducted to eliminate similar isolates.Results showed that the isolates from the roots of S.rosmarinus belonged to the genera Rothia,Kocuria,Pseudomonas,Staphylococcus,Paenibacillus and Brevibacterium.The bacterial isolates from the shoots of S.rosmarinus belonged to the genera Staphylococcus,Rothia,Stenotrophomonas,Brevibacterium,Halomonas,Planococcus,Planomicrobium and Pseudomonas,which differed from those of the roots.Notably,Staphylococcus,Rothia and Brevibacterium were detected in both roots and shoots,indicating possible migration of some species from roots to shoots.The root-associated bacteria showed higher levels of IAA(indole-3-acetic acid)synthesis compared with those isolated from the shoots,as well as the higher production of ACC(1-aminocyclopropane-1-carboxylate)deaminase.Our findings suggest that halophytic plants are valuable sources for the selection of microbes with a potential to improve plant fitness under saline soils. | Vyacheslav SHURIGIN Dilfuza EGAMBERDIEVA LI Li Kakhramon DAVRANOV Hovik PANOSYAN Nils-Kåre BIRKELAND Stephan WIRTH Sonoko D BELLINGRATH-KIMURA | 2020 | Journal of Arid Land2020，12，5： | 0 |
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