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| 1 | Esophageal squamous cell cancer in a highly endemic region显示文摘AIM: To identify risk factors associated with esophageal cancer in Zambia and association between dietary intake and urinary 8-iso prostaglandin F2α(8-iso PGF2α).METHODS: We conducted a prospective, case control study at the University Teaching Hospital. Subjects included both individuals admitted to the hospital and those presenting for an outpatient upper endoscopy. Esophageal cancer cases were compared to age and sex-matched controls. Cases were defined as patients with biopsy proven esophageal cancer; controls were defined as subjects without endoscopic evidence ofesophageal cancer. Clinical and dietary data were collected using a standard questionnaire, developed a priori. Blood was collected for human immunodeficiency virus(HIV) serology. Urine was collected, and 8-iso PGF2α was measured primarily by enzyme-linked immunosorbent assay and expressed as a ratio to creatinine.RESULTS: Forty five controls(mean age 54.2 ± 15.3, 31 male) and 27 cases(mean age 54.6 ± 16.4, 17 males) were studied. Body mass index was lower in cases(median 16.8) than controls(median 23.2), P = 0.01. Histopathologically, 25/27(93%) were squamous cell carcinoma and 2/27(7%) adenocarcinoma. More cases smoked cigarettes(OR = 11.24, 95%CI: 1.37-92.4, P = 0.02) but alcohol consumption and HIV seropositivity did not differ significantly(P = 0.14 for both). Fruit, vegetables and fish consumption did not differ significantly between groups(P = 0.11, 0.12, and 0.10, respectively). Mean isoprostane level was significantly higher in cases(0.03 ng/mg creatinine) than controls(0.01 ng/mg creatinine)(OR = 2.35, 95%CI: 1.19-4.65, P = 0.014).CONCLUSION: Smoking and isoprostane levels were significantly associated with esophageal cancer in Zambians, but diet, HIV status, and alcohol consumption were not. | Akwi W Asombang Violet Kayamba Mpala M Lisulo Kathryn Trinkaus Victor Mudenda Edford Sinkala Stayner Mwanamakondo Themba Banda Rose Soko Paul Kelly | 2016 | World Journal of Gastroenterology2016，22，9： | 2 |
| 2 | Effect of tyre modeling on tractor ride vibration predictions 显示文摘 | Crolla D A Horton D N L Stayner R M | 1990 | Journal of Agricultural Engineering Research1990，47，： | 1 |
| 3 | Mortality among a cohort of garment workers exposed to formaldehyde:an update显示文摘 | Pinkerton LE Hein MJ Stayner LT | 2004 | Occupational d Environmental Medicine2004，61，： | 1 |
| 4 | Lung cancer risk and workplace exposure to environmental tobacco smoke显示文摘 | Leslie Stayner James Bena MS | 2007 | American Journal of Public Health2007，97，3： | 1 |
| 5 | Occupational exposure to cHRysotile asbestos and cancer risk: a review of the amphibole hypothesis显示文摘 | STAYNER L T DANKOVlC D A LEMEN R A | | Am J Public Health0，86，2： | 1 |
| 6 | Lung cancer risk and work- place exposure to environmental tobacco smoke 显示文摘 | Leslie Stayner James Bena MS | 2007 | Ameri- can Journal of Public Health2007，97，3： | 1 |
| 7 | Occupational exposure to asbestos and ovarian cancer:a meta-analysis 显示文摘 | Camargo MC Stayner LT Straif K | 2011 | Environ Health Perspect2011，119，9： | 1 |
| 8 | Risk of suicide attempt in asthmatic children and young adults prescribed leukotriene-modifying agents:a nested case-control study 显示文摘 | Schumock GT Stayner LT Valuck R J | 2012 | J Allergy Clin Immunol2012，130，2： | 1 |
| 9 | Lung cancer risk and workplace exposure to environmental tobacco smoke 显示文摘 | Stayner L Bena J Sasco AJ | 2007 | American Journal of Public Health2007，97，3： | 1 |
| 10 | Cancer morbidity in iron and steel workers in Korea 显示文摘 | Ahn Y S Park R M stayner L | 2006 | American Journal of Industal Medicine2006，49，8： | 1 |
| 11 | Hexavalent chromium and lung cancer in the chromate industry: a quantitative risk assessment显示文摘 | PARK R M BENA J F STAYNER L T | 2004 | Risk Anal2004，24，5： | 1 |
| 12 | Assessment of silicosis risk for occupational exposure to silica 显示文摘 | Rice F L Stayner L T | 1995 | Scand J Work Environ Health1995，21，2： | 1 |
| 13 | Nasopharyngeal cancer,sinonasal cancer and occupation related to formaldehyde:a case control study显示文摘 | Roush GC Walrath J Stayner LT | | 0，，06： | 1 |
| 14 | Cancer morbidity in iron and steel workers in Korea显示文摘 | Ahn Y S Park R M stayner L | 2006 | American Journal of Industel Medicine2006，49，8： | 1 |
| 15 | Clonimg and characterization of the human pax2 promoter显示文摘 | Cherie K Stayner Heather E | 1998 | J Biol Chem1998，273，25： | 1 |
| 16 | Nasal cancer in aworker exposed to formaldehyde显示文摘 | HALPERIN W E GOODMAN M STAYNER L | 1983 | The Journal of the American MedicalAssociation1983，249，4： | 1 |
| 17 | Diesel Exhaust and Lung Cancer in The Trucking Industry: Exposure - Response Analyses and Risk Assessment显示文摘 | Deddens J Stayner L | 1998 | American Journal of Industrial Medicine1998，34，： | 1 |
| 18 | Lung Cancer Risk and Workplace Exposure to Environmental Tobacco Smoke显示文摘 | Leslie Stayner PhD James Bena MS | | 0，，03： | 1 |
| 19 | Mortality among a cohort of garment workers exposed to formaldehyde: an update 显示文摘 | Pinkenon LE Hein MJ Stayner LT | 2004 | Occup Environ Med2004，61，： | 1 |
| 20 | Lung cancer risk and workplace exposure to environmental tobacco smoke显示文摘 | Stayner L Bena J Sasco A J | 2007 | AJPH2007，97，3： | 1 |
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