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| 1 | Intestinal barrier in inflammatory bowel disease显示文摘A complex mucosal barrier protects as the first line of defense the surface of the healthy intestinal tract from adhesion and invasion by luminal microorganisms.In this review,we provide an overview about the major components of this protective system as for example an intact epithelium,the synthesis of various antimicrobial peptides(AMPs)and the formation of the mucus layer.We highlight the crucial importance of their correct functioning for the maintenance of a proper intestinal function and the prevention of dysbiosis and disease.Barrier disturbances including a defective production of AMPs,alterations in thickness or composition of the intestinal mucus layer,alterations of pattern-recognition receptors,defects in the process of autophagy as well as unresolved endoplasmic reticulum stress result in an inadequate host protection and are thought to play a crucial role in the pathogenesis of the inflammatory bowel diseases Crohn’s disease and ulcerative colitis. | Lena Antoni Sabine Nuding Jan Wehkamp Eduard F Stange | 2014 | World Journal of Gastroenterology2014，20，5： | 33 |
| 2 | Extraintestinal manifestations and complications in inflammatory bowel diseases显示文摘Crohn 的疾病(CD ) 和 ulcerative (UC ) 是经常包含胃肠道的除那些以外的机关的长期的煽动性的肠疾病(IBD ) 。这些非肠的爱被称为额外的肠的症状。把煽动性的肠疾病的真额外的肠的表明区分开来与第二等的额外的肠的复杂并发症,由治疗的营养不良,慢性炎或副作用引起了,可能困难。这评论在煽动性的肠疾病专注于频率,临床的演讲和额外的肠的症状的治疗学的含意。如果可能,肠的表明被区分开来与额外的肠的复杂并发症。特殊注意被给参与的更最近描述的地点;即中枢神经系统的 thromboembolic 事件,骨质疏松症,肺的参与和爱。 | Katja S Rothfuss Eduard F Stange Klaus R Herrlinger | 2006 | World Journal of Gastroenterology2006，12，30： | 26 |
| 3 | Food supply and seawater pCO2 impact calcification and internal shell disso- lution in the blue mussel Mytilus edulis显示文摘 | MELZNER F STANGE P TRUBENBACH K | 2011 | PLoS ONE2011，6，24： | 1 |
| 4 | European evidence based consensus on the diagnosis and management of Crohn's disease:current management显示文摘 | Travis SPL Stange E F Lémann M | 2006 | Gut2006，55，： | 1 |
| 5 | Analysis of an Orthotropic Deck Stiffened with a Cement-based Overlay 显示文摘 | WALTER R OLESEN J F STANG H | 2007 | Journal of Bridge Engineering2007，12，3： | 1 |
| 6 | The dorsal flag flap for skin coverage of finger and thumb - tip injuries 显示文摘 | STANG F RAB M VAN SCHOONHOVEN J | 2008 | Oper Orthop Traumatol2008，20，3： | 1 |
| 7 | Short term competition between crop plants and soil microbes for inorganic N fertilizer 显示文摘 | Inselsbaeher E Umana N H Stange F C | 2010 | Soil Biol Biochem2010，42，： | 1 |
| 8 | A process-oriented model of N2O and NO emissions from forest soils: 2, Sensitivity analysis and validation显示文摘 | LI C S ABER J STANGE F | 2000 | Journal of Geophysical Research2000，105，： | 1 |
| 9 | Evaluation of nitrate and ammonium as sources of NO and N2O emissions from black earth soils(Haplic Chernozem)based on 15N field experiments显示文摘 | RUSSOW R SPOTT O STANGE G F | 2008 | Soil Biology and Biochemistry2008，40，2： | 1 |
| 10 | Evaluation of nitrate and ammonium as sources of NO and N20 emissions from black earth soils (Haplic Chemozem) based on 15N field experiments显示文摘 | Russow R Spott O Stange C F | 2008 | Soil Biology & Biochemistry2008，40，2： | 1 |
| 11 | Regional inventory of nitric oxide and nitrous oxide emissions for forest soils of south-east Germany using the biogeochemical model PnET-NDNDC显示文摘 | BUTTERBACH-BAHL K STANGE F PAPEN H | 2001 | Journal of Geophysical Research2001，1，06： | 1 |
| 12 | European evidence based consensus pn the diagnosis and management of Crohn' s disease : current management显示文摘 | Trvis S P L Stang E F L6mann M | 2006 | Gut2006，，： | 1 |
| 13 | Staging colorectal cancer with the TNM 7^(th):The presumption of innocence when applying the M category显示文摘One of the main changes of the current TNM-7 is the elimination of the category MX,since it has been a source of ambiguity and misinterpretation,especially by pathologists.Therefore the ultimate staging would be better performed by the patient's clinician who can classify the disease M0(no distant metastasis) or M1(presence of distant metastasis),having access to the completeness of data resulting from clinical examination,imaging workup and pathology report.However this important change doesn't take into account the diagnostic value and the challenge of small indeterminate visceral lesions encountered,in particular,during radiological staging of patients with colorectal cancer.In this article the diagnosis of these lesions with multiple imaging modalities,their frequency,significance and relevance to staging and disease management are described in a multidisciplinary way.In particular the interplay between clinical,radiological and pathological staging,which are usually conducted independently,is discussed.The integrated approach shows that there are both advantages and disadvantages to abandoning the MX category.To avoid ambiguity arising both by applying and interpreting MX category for stage assigning,its abandoning seems reasonable.The recognition of the importance of small lesion characterization raises the need for applying a separate category;therefore a proposal for their categorization is put forward.By using the proposed categorization the lack of consideration for indeterminate visceral lesions with the current staging system will be overcome,also optimizing tailored follow-up. | Giacomo Puppa Graeme Poston Per Jess Guy F Nash Kenneth Coenegrachts Axel Stang | 2013 | World Journal of Gastroenterology2013，19，8： | 1 |
| 14 | Regional inventory of nitric oxide and nitrous oxide emissions for forest soils of south-east Germany using the biogeochemical model PnET-NDNDC显示文摘 | Stange F Papen H | 2001 | Journal of Geophysical Research2001，106，34： | 1 |
| 15 | Analysis of complex leaf and flower characters in Rhododendron using a molecular linkage map显示文摘 | Dunemann F Kahnau R Stange I | 1999 | Springer-Verlag Heidelberg1999，98，67： | 1 |
| 16 | European evidence based consensus on the diagnosis and management of Crohn's disease: current management显示文摘 | Travis S P L Stange E F Lemann M | 2006 | Gut2006，55，1： | 1 |
| 17 | S3-Leitlinie ?Diagnostik und Therapie des Morbus Crohn”显示文摘 | J Hoffmann J Prei? F Autschbach H Buhr W H?user K Herrlinger W H?hne S Koletzko C Krieglstein W Kruis H Matthes G Moser M Reinshagen G Rogler S Schreiber A Schreyer B Sido B Siegmund A Stallmach B Bokemeyer E Stange M Zeitz | 2008 | Z Gastroenterol2008，，09： | 1 |
| 18 | Light affected the compotation for inorganic and organic nitrogen between maize and soil microorganisms显示文摘 | Xu X L Kuzyakov Y Stange F | 2008 | Plant and Soil2008，304，： | 1 |
| 19 | Transdifferentiated mesenchymal stem cells as altemativetherapy in supporting nerve regeneration and myelination 显示文摘 | Keilhoff G Stang F Goihl A | 2006 | Cell Mol Neurobiol2006，26，： | 1 |
| 20 | Seasonal variation in nitrification and nitrate-reduction pathways in coastal sediments in the Gulf of Finland, Baltic Sea显示文摘 | Jantti H Stange F Leskinen E | 2011 | Aquatic Microbial Ecology2011，63，2： | 1 |
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