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| 1 | Parkin gene alterations in hepatocellular carcinoma显示文摘 | Wang F Stacy D Lai JP | 2004 | Genes Cheomosomaes & Cancer2004，40，2： | 1 |
| 2 | Ordered mesoprous alumina-supported metal oxides 显示文摘 | Stacy M Morris Pasquale F Fulvio Mietek Jaroniec | 2008 | J Am Chem Soc2008，1340，15： | 1 |
| 3 | The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity显示文摘 | Beck Stacy Wojdyla Daniel Say Lale Betran Ana Pilar Merialdi Mario Requejo Jennifer Harris Rubens Craig Menon Ramkumar Van Look Paul F A | 2010 | Bulletin of the World Health Organization2010，，1： | 1 |
| 4 | Serological profiling of Crohn’s disease and ulcerative colitis patients reveals anti-microbial antibody signatures显示文摘BACKGROUND The healthcare burden of inflammatory bowel disease(IBD)is rising globally and there are limited non-invasive biomarkers for accurate and early diagnosis.AIM To understand the important role that intestinal microbiota play in IBD pathogenesis and identify anti-microbial antibody signatures that benefit clinical management of IBD patients.METHODS We performed serological profiling of 100 Crohn’s disease(CD)patients,100 ulcerative colitis(UC)patients and 100 healthy controls against 1173 bacterial and 397 viral proteins from 50 bacteria and 33 viruses on protein microarrays.The study subjects were randomly divided into discovery(n=150)and validation(n=150)sets.Statistical analysis was performed using R packages.RESULTS Anti-bacterial antibody responses showed greater differential prevalence among the three subject groups than anti-viral antibody responses.We identified novel antibodies against the antigens of Bacteroidetes vulgatus(BVU_0562)and Streptococcus pneumoniae(SP_1992)showing higher prevalence in CD patients relative to healthy controls.We also identified antibodies against the antigen of Streptococcus pyogenes(SPy_2009)showing higher prevalence in healthy controls relative to UC patients.Using these novel antibodies,we built biomarker panels with area under the curve(AUC)of 0.81,0.87,and 0.82 distinguishing CD vs control,UC vs control,and CD vs UC,respectively.Subgroup analysis revealed that penetrating CD behavior,colonic CD location,CD patients with a history of surgery,and extensive UC exhibited highest antibody prevalence among all patients.We demonstrated that autoantibodies and anti-microbial antibodies in CD patients had minimal correlation.CONCLUSION We have identified antibody signatures for CD and UC using a comprehensive analysis of antimicrobial antibody response in IBD.These antibodies and the source microorganisms of their target antigens improve our understanding of the role of specific microorganisms in IBD pathogenesis and,after future validation,should aid early and accurate diagnosis of IBD. | Mahasish Shome Lusheng Song Stacy Williams Yunro Chung Vel Murugan Jin G Park William Faubion Shabana F Pasha Jonathan A Leighton Joshua LaBaer Ji Qiu | 2022 | World Journal of Gastroenterology2022，28，30： | 1 |
| 5 | Making energy conservation pay through automation 显示文摘 | FUNK G L HONSTON B F STACY G D | 1978 | Chemical Engineering Process1978，74，5： | 1 |
| 6 | Prices,incentives and choice of management form显示文摘 | Sirmans C F Turnbull Geoffrey K | 1999 | Regional Science and Urban Economics1999，29，2： | 1 |
| 7 | Enhanced circulating half-life and antitu- mor activity of a site-specific pegylated interferon- protein therapeutic显示文摘 | STACIE J B CHRISTINE M F ELIZABETH A C | 2008 | Bioconjugate Chem2008，19，1： | 1 |
| 8 | Informa- tion Quality Issues in Municipal Governments显示文摘 | Stacy F Hobson Rangachari Anand Xuan Liu | 2011 | IEEE2011，，： | 1 |
| 9 | Is iron gluconate really safer than iron dextran显示文摘 | Quentin E Stacy F Sunny D | 2003 | Blood2003，101，9： | 1 |
| 10 | Finite strain theory and comparison with seismological data 显示文摘 | STACY F D BRENNAN B J | 1981 | Geophysic1981，4，： | 1 |
| 11 | The K - primed approach to high pressure equations of state 显示文摘 | STACY F D | 2000 | Phys J Int2000，143，： | 1 |
| 12 | Finite strain thermodynamics and the earth's core 显示文摘 | STACY F D | 2001 | Phys Earth Planet Int2001，128，： | 1 |
| 13 | High pressure equations of state with application to lower mantle and the earth 显示文摘 | STACY F D DAVIS P M | 2004 | Phys Earth Planet Int2004，142，： | 1 |
| 14 | Cyclosporin A is a broad-spectrum multidrug resistance modulator显示文摘 | Misbah Q Kieran O Stacy F | 2005 | Clin Cancer Res2005，11，： | 1 |
| 15 | Prices, incentives and choice of management显示文摘 | G Stacy Sirmans C F Sirmans Geoffrey K Turnbull | 1999 | Regional Science & Urban Economics1999，29，2： | 1 |
| 16 | Differential Expression of SPARC in intestinal-type gastric cancer correlates with tumor progression and nodal spread显示文摘 | KONRAD F STACY C M FRIEDRICH-WILHELM R | 2009 | Translational Oncology2009，2，4： | 1 |
| 17 | Effectiveness of purge-and-trap for measurement of volatile organic compounds in aged soils显示文摘 | Minoo D F Askari Michael P Maskarinec Stacy M Smith | 1996 | A ncd Chem1996，68，： | 1 |
| 18 | Interaction of sulfur dioxide with active carbon显示文摘 | Stacy W O Vastola F J Walker Jr P L | 1968 | Carbon1968，6，6： | 1 |
| 19 | Runxl expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo 显示文摘 | NORTH T E DE BRUIJN M F STACY T | 2002 | Immunity2002，16，5： | 1 |
| 20 | Cyclosporin A is a Broad-Spectrum Muhidrug Resistance Modulator显示文摘 | Misbah Q Kieran O Stacy F | 2005 | Clin Cancer Res2005，11，6： | 1 |
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