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| 1 | Gossypol inhibits proliferation of endometrioma cells in culture显示文摘瞄准:为了在子宫内膜瘤评估 anti-proliferative 活动和棉子酚的 mitochondrial 毒性,房间在短期的文化维持了。方法:三 endometriomacell 从病人衬里的(A) 与 25 或 50 nmol/L 棉子酚被对待多达 12 天。细胞生长上的棉子酚的效果被记录。(B) A 磷光氧分析器被用来从病人在六根子宫内膜瘤房间线的 mitochondrial 耗氧量上决定棉子酚的效果。(C) 在从病人的三根子宫内膜瘤房间线的细胞的棉子酚累积被高压的液相色谱法测量。结果:endometriomacells 的增长被 25 和 50 nmol/L 棉子酚禁止。子宫内膜瘤房间的呼吸被 10 μ m ol/L 棉子酚禁止。细胞的棉子酚在与 10 和 0.3 μ m ol/L 棉子酚为 24 h 被对待的子宫内膜瘤房间线被检测。结论:棉子酚在有教养的子宫内膜瘤房间上调用有势力毒性。 | Shawky Z. A. Badawy Abdul-Kader Souid Violeta Cuenca Nicholas Montalto Frances Shue | 2007 | Asian Journal of Andrology2007，9，3： | 3 |
| 2 | Profiling cellular bioenergetics, glutathione levels, and caspase activities in stomach biopsies of patients with upper gastrointestinal symptoms显示文摘AIM: To measure biochemical parameters in stomach biopsies and test their suitability as diagnostic biomarkers for gastritis and precancerous lesions.METHODS: Biopsies were obtained from the stomachs of two groups of patients(n = 40) undergoing fiberoptic endoscopy due to upper gastrointestinal symptoms. In the first group(n = 17), only the corpus region was examined. Biopsies were processed for microscopic examination and measurement of mitochondrial O2 consumption(cellular respiration), cellular adenosine triphosphate(ATP), glutathione(GSH), and caspase activity. In the second group of patients(n = 23), both corpus and antral regions were studied. Some biopsies were processed for microscopic examination, while the others were used for measurements of cellular respiration and GSH level.RESULTS: Microscopic examinations of gastric corpus biopsies from 17 patients revealed normal mucosae in 8 patients, superficial gastritis in 7 patients, and chronic atrophic gastritis in 1 patient. In patients with normal histology, the rate(mean ± SD) of cellular respiration was 0.17 ± 0.02 μmol/L O2 min-1 mg-1, ATP content was 487 ± 493 pmol/mg, and GSH was 469 ± 98 pmol/mg. Caspase activity was detected in 3 out of 8 specimens. The values of ATP and caspase activity were highly variable. The presence of superficial gastritis had insignificant effects on the measured biomarkers. In the patient with atrophic gastritis, cellular respiration was high andATP was relatively low, suggesting uncoupling oxidative phosphorylation. In the second cohort of patients, the examined biopsies showed either normal or superficial gastritis. The rate of cellular respiration(O2. μmol/L min-1 mg-1) was slightly higher in the corpus than the antrum(0.18 ± 0.05 vs 0.15 ± 0.04, P = 0.019). The value of GSH was about the same in both tissues(310 ± 135 vs 322 ± 155, P = 0.692).CONCLUSION: The corpus mucosa was metabolically more active than the antrum tissue. The data in this study will help in understanding the pathophysiology of gastric mucosa. | Ali S Alfazari Bayan Al-Dabbagh Wafa Al-Dhaheri Mazen S Taha Ahmad A Chebli Eva M Fontagnier Zaher Koutoubi Jose Kochiyi Sherif M Karam Abdul-Kader Souid | 2015 | World Journal of Gastroenterology2015，21，2： | 2 |
| 3 | In vitro study on the pulmonary cytotoxicity of amiodarone显示文摘 | Alsamri MT Pramathan T Souid AK | 2013 | Toxicol Mech Methods2013，23，8： | 1 |
| 4 | WR-2721 (amifostine) infusion in patients with Ewing’s sarcoma receiving ifosfamide and cyclophosphamide with mesna: drug and thiol levels in plasma and blood cells, a Pediatric Oncology Group study显示文摘 | Abdul-Kader Souid Robert C. Fahey Ronald L. Dubowy Gerald L. Newton Mark L. Bernstein | 1999 | Cancer Chemotherapy and Pharmacology1999，，6： | 1 |
| 5 | Dermoscopic fea-tures of clinically inflammatory dermatoses and their correla-tion with histopathologic reaction patterns 显示文摘 | Goncharova Y Attia EA Souid K | 2015 | Arch Derma-tol Res2015，307，1： | 1 |
| 6 | Allelopathic effects of humus phenolics on growth and respiration of mycorrhizal fungi显示文摘 | SOUID C PELLISSIER F CHIAPUSIO G | 2000 | Journal of Chenmical Ecology2000，26，9： | 1 |
| 7 | Hemolysis-induced a- cute pancrcatitis secondary to kinked hemodialysis blood lines 显示文摘 | Mahdi ABTAHI Martine UZAN Marc SOUID | 2007 | Hemodialysis International2007，11，1： | 1 |
| 8 | Determinationof the cytoprotective agent WR-2721 (Amifostine, Ethyol) and itsmetabolites in human blood using monobromobimane fluorescentlabeling and high-performance liquid chromatography 显示文摘 | SOUID A K NEWTON G L DUBOWY R L | 1998 | CancerChemother Pharmacol1998，42，5： | 1 |
| 9 | Lead accumulation pattern and molecular biomarkers of oxidative stress in seabream (Sparus aurata) under short-term metal treatment显示文摘 | Souid G Souayed N Yaktiti F | 2015 | Drug Chem Toxicol2015，38，1： | 1 |
| 10 | Myeloperoxidase autoantibodies ( MPO-ANCA )-related rapidly progressive glomerulonephritis (RPGN) and pulmonary fibrosis (PF)with dissociated evolution 显示文摘 | Souid M Terki NH Nochy D | 2001 | Clin Nephrol2001，55，4： | 1 |
| 11 | Dermoscopic features of facial pigmented skin lesions显示文摘 | Goncharova Y Attia EA Souid K | 2013 | ISRN Dermatol2013，，54： | 1 |
| 12 | Histiocytic sarcoma in a 3-year-old male:a case report 显示文摘 | Buonocore S Valente AL Nightingale D Bogart J Souid AK | 2005 | Pediatrics2005，116，8： | 1 |
| 13 | Determination Of the cytoprotective agent WR-2721 (amifostine, Ethyol) and its metabolites in human blood using monobromobimane fluorescent labeling and high-performance liquid chromatography 显示文摘 | SOUID A K NEWTON G L DUBOWY R L | 1998 | Cancer Chemo Ther Pharmacol1998，42，： | 1 |
| 14 | Determination Of the cytoprotective agent WR-2721(amifostine,Ethyol)and its metabolites in human blood using monobromobimane fluorescent labeling and high-performance liquid chromatography显示文摘 | Souid A K Newton G L Dubowy R L et al | 1998 | Cancer Chemo Ther Pharmacol1998，42，： | 1 |
| 15 | The xbp-1 gene is essential for development in Drosophila显示文摘 | Sami Souid Jean-Antoine Lepesant Constantin Yanicostas | 2007 | Development Genes and Evolution2007，，2： | 1 |
| 16 | The xbp-1 gene is essential for development in Drosophila显示文摘 | Sami Souid Jean-Antoine Lepesant Constantin Yanicostas | 2007 | Development Genes and Evolution2007，，2： | 1 |
| 17 | In vitro study on the pulmonary cytotoxicity of amiodarone显示文摘 | Msamri MT Pramathan T Souid AK | | 0，，08： | 1 |
| 18 | Optimal temperature forwhole-body hypothermia in the newborn: an in vitro studyusing foreskin mitochondrial oxygen consumption 显示文摘 | Al Zaabi A Rahmani AY Souid A | 2014 | JNeonatal Perinatal Med2014，7，3： | 1 |
| 19 | A generalized model for predicting yarn global quality index显示文摘 | SOUID H SAHNOUN M BABAY A | 2012 | The Open Textile Journal2012，，5： | 1 |
| 20 | Dermoscopic fea-tures of clinically inflammatory dermatoses and their correla-tion with histopathologic reaction patterns显示文摘 | Goncharova Y Attia EA Souid K | 2015 | Arch DermatolRes2015，，： | 1 |
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