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| 1 | NF-κB Signaling Pathway, Inflammation and Colorectal Cancer显示文摘 | Soly Wang Zhanjie Liu Lunshan Wang Xiaoren Zhang | 2009 | Cellular & Molecular Immunology2009,6,5: | 46 |
| 2 | 耳鸣评价量表的临床应用价值研究显示文摘目的探讨耳鸣评价量表(tinnitus evaluation questionnaire,TEQ)的临床应用价值。方法以耳鸣为第一主诉初诊的187例患者(13~80岁,平均42.5±13.5岁)为研究对象,由专业医务人员进行TEQ评估,以患者自填的耳鸣残疾量表(tinnitus handicap inventory,THI)作为对照,研究TEQ的汇聚效度;从中抽取96例患者由两名专业医务人员在半天内对同一患者进行2次TEQ评估,评估耳鸣严重程度,以比较不同测试者间的重测信度;抽取57例患者给予治疗一个月,根据治疗前后患者主观感觉耳鸣有无变化,应用效应量(effect size,ES)计算公式评估TEQ反应度(responsiveness);记录TEQ评估每位患者的测试用时及患者自填THI的时间,以比较测试时效。结果 187例患者TEQ、THI总分分别为10.69±2.88和43.12±19.40,相关系数r=0.79(P<0.01),TEQ与THI汇聚效度好;接受两名测试者评估的96例患者不同测试者间TEQ重测信度为0.94(P<0.01),TEQ的重测信度良好;57例患者治疗一个月后自觉耳鸣症状改善组(36例)治疗前TEQ得分10.69±2.74分,治疗后为7.83±2.74分,效应量为1.04,为较大效应量;说明TEQ能敏感反映患者症状变化,反应度良好。TEQ评估时间(3.27±1.01分钟)显著短于THI评估时间(11.17±3.11分钟)(P<0.01)。结论 TEQ的准确性、可靠性、敏感性及可操作性均较理想,且费时少,具有良好的临床实用价值,适用于对耳鸣严重程度和疗效的评估。 | 陈知己 郑芸 钟萍 李刚 Sigfrid D Soli | 2017 | 听力学及言语疾病杂志2017,25,3: | 38 |
| 3 | 简易版普通话早期言语感知测试(LV-MESP)的临床应用简介显示文摘儿童时期是听觉-言语-语言能力发育的重要时期,幼儿期的言语发育尤为关键[1,2]。听障幼儿言语语言的成功康复需要早期干预。普遍新生儿听力筛查的开展、助听器和人工耳蜗等各种早期干预技术的迅速发展和推广,使听障幼儿的早期诊断和干预成为可能。 | 郑芸 孟照莉 王恺 Sigfrid D. Soli | 2012 | 听力学及言语疾病杂志2012,20,3: | 9 |
| 4 | 噪声条件下听力测试的应用显示文摘 | Wong LN Chan CY Soli SD | 2009 | 听力学及言语疾病杂志2009,17,4: | 5 |
| 5 | Molecular mechanism of extrinsic factors affecting antiaging of stem cells显示文摘Scientific evidence suggests that stem cells possess the anti-aging ability to self-renew and maintain differentiation potentials, and quiescent state. The objective of this review is to discuss the microenvironment where stem cells reside in vivo, the secreted factors to which stem cells are exposed, thehypoxic environment, and intracellular factors including genome stability, mitochondria integrity, epigenetic regulators, calorie restrictions, nutrients, and vitamin D. Secreted tumor growth factor-β and fibroblast growth factor-2 are reported to play a role in stem cell quiescence. Extracellular matrices may interact with caveolin-1, the lipid raft on cell membrane to regulate quiescence. N-cadherin, the adhesive protein on niche cells provides support for stem cells. The hypoxic micro-environment turns on hypoxia-inducible factor-1 to prevent mesenchymal stem cells aging through p16 and p21 down-regulation. Mitochondria express glucosephosphate isomerase to undergo glycolysis and prevent cellular aging. Epigenetic regulators such as p300, protein inhibitors of activated Stats and H19 help maintain stem cell quiescence. In addition, calorie restriction may lead to secretion of paracrines cyclic ADP-ribose by intestinal niche cells, which help maintain intestinal stem cells. In conclusion, it is crucial to understand the anti-aging phenomena of stem cells at the molecular level so that the key to solving the aging mystery may be unlocked. | Tzyy Yue Wong Mairim Alexandra Solis Ying-Hui Chen Lynn Ling-Huei Huang | 2015 | World Journal of Stem Cells2015,7,2: | 4 |
| 6 | Evaluation of sexual function in subjects taking finasteride for the treatment of androgenetic alopeeia显示文摘 | Tosti A Piraceini BM Soli M | 2001 | J Eur Acad Dermatol Venereol2001,15,5: | 1 |
| 7 | Polyploid recurrent formation and genome evolution显示文摘 | Solis D E Soltis P S | 1999 | Trends in Ecology and Evolution1999,14,: | 1 |
| 8 | Is anticoagulation indicated for asymptomatic postoperative calf vein thrombosis? 显示文摘 | SOLIS MM RANVAL TJ NIX ML | 1992 | J Vase Surg1992,16,3: | 1 |
| 9 | Crude Oil Market Efficiency and Modeling:Insights from the Multiscaling Autocorrelation Pattern显示文摘 | Jose Alvarez-Ramirez Jesus Alvarez Ricardo Solis | | 0,,05: | 1 |
| 10 | Anormative study of early prelingual auditory development显示文摘 | Zheng Y Soli SD Wang K | 2009 | Audiol Neurootol2009,14,: | 1 |
| 11 | Numerical Study on Pressure Fluctuations Reduction in Centrifugal Pumps: Influence of Radial Gap and Splitter Blades显示文摘 | Solis M Bakir F Khelladi S | 2011 | ISRN Mechanical Engineering2011,2011,: | 1 |
| 12 | Minimization by random research techniques显示文摘 | Solis F Wets R | 1981 | Mathematics of Operations Research1981,6,1: | 1 |
| 13 | Submeter spatial variability of selected soil and bermudagrass production variables显示文摘 | Solie J B Raun W R Stone M L | 1999 | Soil Sci Soc Am J1999,63,: | 1 |
| 14 | Continuous model update of natural fractures characterization in Sinan field to optimize production 显示文摘 | Solis S | 2005 | SPE969632005,,: | 1 |
| 15 | Kinetics and Mechanism of Low - temperature SCR of NO with NH, Over Vanadium Oxide Supported on Carbon - ceramic Cellular Monoliths 显示文摘 | Valdes - Solis T Marban G Fuertes A B | 2004 | Ind EngChem Res2004,43,10: | 1 |
| 16 | Minimization by random search techniques 显示文摘 | Solis F J Wets R J B | 1981 | Mathematics of Operations Research (S0364-765X)1981,6,1: | 1 |
| 17 | Mitochondiral KATP dependent potassium channels mediate non-ischemio preconditioning by tachycardia in dogs 显示文摘 | Macho P Solis E Sanchez O | 2001 | Mol Cell Biochem2001,216,: | 1 |
| 18 | PIXE Analysis of Zn Enzymes显示文摘 | Solis C Oliver A Andrade E | 1999 | Nucl Instrum Meth B1999,150,: | 1 |
| 19 | Characterization and protective potential of the immune response to Taenia solium paramyosin in a murine model of Cysticercosis显示文摘 | VAZQUEZ-TALAVERA J SOLIS C F TERRAZAS L I | 2001 | Infect Immun2001,69,: | 1 |
| 20 | The Trans- Pacific Partnership: Can the UnitedStates Lead the Way in Asia - Pacific Integration显示文摘 | Mireya Solis | 2012 | Pacific Focus2012,,3: | 1 |