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| 1 | Analysis of bacterial communities on aging flue-cured tobacco leaves by 16S rDNA PCR-DGGE technology显示文摘 | Zhao MQ Wang BX Li FX Qiu LY Li FF Wang SM Cui JK | 2007 | 中国生物学文摘2007，21，9： | 23 |
| 2 | Orthotopic liver transplantation for fulminant hepatitis B显示文摘INTRODUCTION When fulminant hepatitis progress to deep encephalopathy,with stage Ⅲ or Ⅳ coma,it is commonly irreversible with a high mortality rate(80%-100%).Liver transplantation may be | He XS Huang JF Chen GH Fu Q Zhu XF Lu MQ Wang GD Guan XD | 2000 | World Journal of Gastroenterology2000，6，3： | 14 |
| 3 | Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility:A meta-analysis显示文摘AIM: To assess the association between Interleu-kin-10 (IL-10) gene IL-10-1082 (G/A), IL-10-592(C/A), IL-10-819 (T/C) polymorphisms and hepatocellular carcinoma (HCC) susceptibility.METHODS: Two investigators independently searched the Medline, Embase, China National Knowledge Infrastructure, and Chinese Biomedicine Database. Summary odds ratios (ORs) and 95% conf idence intervals (95% CIs) for IL-10 polymorphisms and HCC were cal-culated in a fixed-effects model (the Mantel-Haenszel method) and a random-effects model (the DerSimonian and Laird method) when appropriate. RESULTS: This meta analysis included seven eligiblestudies, which included 1012 HCC cases and 2308 controls. Overall, IL-10-1082 G/A polymorphism was not associated with the risk of HCC (AA vs AG + GG, OR = 1.11, 95% CI = 0.90-1.37). When stratifying for ethnicity, the results were similar (Asian, OR = 1.12, 95% CI = 0.87-1.44; non-Asian, OR = 1.10, 95% CI = 0.75-1.60). In the overall analysis, the IL-10 polymorphism at position -592 (C/A) was identified as a genetic risk factor for HCC among Asians; patients carrying the IL-10-592*C allele had an increased risk of HCC (OR = 1.29, 95% CI = 1.12-1.49). No association was observed between the IL-10-819 T/C polymorphism and HCC susceptibility (TT vs TC + CC, OR = 1.02, 95% CI = 0.79-1.32).CONCLUSION: This meta-analysis suggests that IL-10-592 A/C polymorphism may be associated with HCC among Asians. IL-10-1082 G/A and IL-10-819 T/C polymorphisms were not detected to be related to the risk for HCC. | Yong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin YangYong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin Yang, Department of Liver and Vascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Prov- ince, China Author contributions: Wei YG and Liu F designed the study, collected and analyzed the data and wrote the manuscript Li B collected and analyzed the data and wrote the manuscript Chen X and Ma Y collected and analyzed the data Yan LN analyzed the data and contributed to the discussion Wen TF and Xu MQ revised the manuscript Wang WT and Yang JY contributed to the discussion Wei YG and Liu F contributed equally to this work. | 2011 | World Journal of Gastroenterology2011，17，34： | 3 |
| 4 | VP22的细胞间传递作用对HSV-tk/GCV的肿瘤细胞杀伤促进效应显示文摘目的 :探讨VP2 2的细胞间传递作用对HSV tk/GCV杀伤肿瘤细胞的促进作用。方法 :将VP2 2与报告基因 绿色荧光蛋白基因 (GFP)或前药酶基因 单纯疱疹病毒胸苷激酶基因 (HSV tk)构建在同一载体上 ,进行DNA序列分析鉴定 ;将此融合基因载体转染 2 93T或COS7细胞 ,免疫荧光分析确定转染情况和细胞间传递作用 ;在前药GCV不同浓度、转染与未转染细胞比例不同时 ,MTT法检测细胞增殖情况 ;利用转染细胞培养液上清培养未转染细胞 ,确定旁观者效应是否由培养液转移。结果 :PCR及序列分析显示融合基因插入载体正确 ;对 2 93T或COS7细胞转染率可达 2 5 %~ 3 0 % ,且证明融合蛋白已被表达并在细胞间传递 ;HSV tk与VP2 2融合后在前药GCV浓度低至 0 .1μg/ml时就可显示出细胞杀伤效应增强 ,并随着表达VP2 2 HSV tk细胞比例的增加 ,细胞杀伤作用增强。结论 :VP2 2介导的自杀基因产物的细胞间传递作用可解决自杀基因的低效细胞毒作用 ,明显增强细胞杀伤效应。 | 刘春生 孔北华 马道新 王文霞 MQ Wei KAO Ellem | 2001 | 中国肿瘤生物治疗杂志2001，8，2： | 2 |
| 5 | Alpha-2 adrenergic receptor activation by brimonidine reduces neuronal apoptosis by inducing new protein synthesis that maintains mitochondrial pore closure显示文摘 | Chalmers-Redman RME Elstner MQ Mammen M | 2000 | Exp Eye Res2000，71，： | 2 |
| 6 | Thermodynamic Aspect in Synthesis of AlN Powders by Carbothermal Reduction and Nitridation Process显示文摘A thermodynamical calculation shows that AlN powders were synthesized in the process bythe overall reaction Al2O3(s)+3C(s)+N2(g)=2AlN(s)+3CO(g) and its minimum reaction tem-perature T0=1852 K, if all reactants and products were in standard states. ln the practicalexperiments, AlN phase appeared obviously at only 1300℃, the major reasons are related to thepartial pressure of its gaseous product pco and the mixed free energy. The synthesis temperaturecould be lowered by either increasing N2 flow rate or elevating N2 pressure. On the other hand,as the temperature decreases, the equilibrium constant Km also reduces, and the reducing ratestrongly depends on the temperature: the lower the temperature, the higher the rate. | Dai, XM Li, QF Ding, MQ Tian, JM | 1999 | Journal of Materials Science & Technology1999，15，1： | 2 |
| 7 | POEMS syndrome:definitions and long-term outcome显示文摘 | Dispenzieri A Kyle RA Lacy MQ | 2003 | Blood2003，101，7： | 1 |
| 8 | Association between symptom severity and internal capsule volume in obsessive-compulsive disorder显示文摘 | Duran FL Hoexter MQ Valente AA Jr | 2009 | Neurosci Lett2009，452，1： | 1 |
| 9 | POEMS syndrome:definitions and long-term outcome显示文摘 | Dispenzieri A Kyle RA Lacy MQ et ai | 2003 | Blood2003，101，7： | 1 |
| 10 | Rapamycin inhibits cell growth by induction of apoptosis on hepatocellular carcinoma cells in vitro显示文摘 | Zhang JF Liu JJ Lu MQ | 2007 | Transpl Immunol2007，17，3： | 1 |
| 11 | Does the relation of blood pressure to coronary heart disease risl change with haging? The Framinghan Heart Study显示文摘 | Franklin SS Larson MQ Khan SA | 2001 | Circulation2001，103，： | 1 |
| 12 | POEMS syndrome:definition and long-term outcome显示文摘 | Dispenzieri A Kyle RA Lacy MQ | 2003 | Blood2003，101，7： | 1 |
| 13 | Crystal structure of a minmi-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing显示文摘 | Ding Y Xu MQ Ghosh I | 2003 | J Biol Chem2003，278，39： | 1 |
| 14 | POEMS syndrome: definitions and long-term outcome 显示文摘 | Dispenzieri A Kyle RA Lacy MQ | 2003 | Blood2003，101，7： | 1 |
| 15 | POEMS syndrome:definition and long-term outcome显示文摘 | Dispenzieri A Kyle RA Lacy MQ | 2003 | Blood2003，101，7： | 1 |
| 16 | Design and fabrica-tion of magnetic nanoparticles for targeted drug delivery and ima-ging 显示文摘 | VEISEH O GUNN JW ZHANG MQ | 2010 | Adv Drug Deliv Rev2010，62，3： | 1 |
| 17 | Prenatal malnutrition and adult schizophrenia: further evidence from the 1959-1961 Chinese famine显示文摘 | Xu MQ Sun WS Liu BX | 2009 | Schizophr Bull2009，35，3： | 1 |
| 18 | Epicardial fat can mimic peri-cardial effusion on transoesophageal echocardiogram显示文摘 | Najib MQ Ganji JL Raizada A | 2011 | Eur J Echocar-diogr2011，12，10： | 1 |
| 19 | Altered baseline brain activity in children with ADHD revealed by resting- state functional MRI显示文摘 | Zang YF He Y Zhu CZ Cao QJ Sui MQ Liang M | 2007 | Brain Dev2007，29，2： | 1 |
| 20 | A phase I study of docetaxel and bexarotene显示文摘 | Wildi JD Baggstrom MQ Suresh R | 2008 | Chemotherapy2008，54，： | 1 |
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