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| 1 | Opisthorchiasis and Opisthorchis -associated cholangiocarcinoma in Thailand and Laos显示文摘 | Banchob Sripa Jeffrey M. Bethony Paiboon Sithithaworn Sasithorn Kaewkes Eimorn Mairiang Alex Loukas Jason Mulvenna Thewarach Laha Peter J. Hotez Paul J. Brindley | 2010 | Acta Tropica2010,,: | 2 |
| 2 | Thinking beyond Opisthorchis viverrini for risk of cholangiocarcinoma in the lower Mekong region:a systematic review and meta-analysis显示文摘Background:Cholangiocarcinoma(CCA)is a fatal bile duct cancer associated with infection by the liver fluke,Opisthorchis viverrini,in the lower Mekong region.Numerous public health interventions have focused on reducing exposure to O.viverrini,but incidence of CCA in the region remains high.While this may indicate the inefficacy of public health interventions due to complex social and cultural factors,it may further indicate other risk factors or interactions with the parasite are important in pathogenesis of CCA.This systematic review aims to provide a comprehensive analysis of described risk factors for CCA in addition to O.viverrini to guide future integrative interventions.Main body:We searched five international and seven Thai research databases to identify studies relevant to risk factors for CCA in the lower Mekong region.Selected studies were assessed for risk of bias and quality in terms of study design,population,CCA diagnostic methods,and statistical methods.The final 18 included studies reported numerous risk factors which were grouped into behaviors,socioeconomics,diet,genetics,gender,immune response,other infections,and treatment for O.viverrini.Seventeen risk factors were reported by two or more studies and were assessed with random effects models during meta-analysis.This meta-analysis indicates that the combination of alcohol and smoking(OR=11.1,95%CI:5.63-21.92,P<0.0001)is most significantly associated with increased risk for CCA and is an even greater risk factor than O.viverrini exposure.This analysis also suggests that family history of cancer,consumption of raw cyprinoid fish,consumption of high nitrate foods,and praziquantel treatment are associated with significantly increased risk.These risk factors may have complex relationships with the host,parasite,or pathogenesis of CCA,and many of these risk factors were found to interact with each other in one or more studies.Conclusions:Our findings suggest that a complex variety of risk factors in addition to O.viverrini infection should be addressed in future public health interventions to reduce CCA in affected regions.In particular,smoking and alcohol use,dietary patterns,and socioeconomic factors should be considered when developing intervention programs to reduce CCA. | Jennifer A.Steele Carsten H.Richter Pierre Echaubard Parichat Saenna Virginia Stout Paiboon Sithithaworn Bruce A.Wilcox | 2018 | Infectious Diseases of Poverty2018,7,1: | 2 |
| 3 | Risk factors for cholangiocarcinoma in high-risk area of Thailand: Role of lifestyle, diet and methylenetetrahydrofolate reductase polymorphisms显示文摘 | Nopparat Songserm Supannee Promthet Paiboon Sithithaworn Chamsai Pientong Tipaya Ekalaksananan Peechanika Chopjitt Donald Maxwell Parkin | 2011 | Cancer Epidemiology2011,,2: | 1 |
| 4 | An ecological study of Bithynia snails, the first intermediate host of Opisthorchis viverrini in northeast Thailand显示文摘 | Yi-Chen Wang Richard Cheng Yong Ho Chen-Chieh Feng Jutamas Namsanor Paiboon Sithithaworn | 2014 | Acta Tropica2014,,: | 1 |
| 5 | Ultrasonography assessment of hepatobiliary abnormalities in 3359 subjects with Opisthorchis viverrini infection in endemic areas of Thailand显示文摘 | Eimorn Mairiang Thewarach Laha Jeffrey M. Bethony Bandit Thinkhamrop Sasithorn Kaewkes Paiboon Sithithaworn Smarn Tesana Alex Loukas Paul J. Brindley Banchob Sripa | 2011 | Parasitology International2011,,1: | 1 |
| 6 | The ecology of the Bithynia first intermediate hosts of Opisthorchis viverrini显示文摘 | Trevor Petney Paiboon Sithithaworn Ross Andrews Nadda Kiatsopit Smarn Tesana Carl Grundy-Warr Alan Ziegler | 2011 | Parasitology International2011,,1: | 1 |
| 7 | Towards improved diagnosis of zoonotic trematode infections in southeast asia显示文摘 | Johansen MV Sithithaworn P Bergquist R | 2010 | Adv Parasitol2010,73,: | 1 |
| 8 | Roles of liver fluke infection as risk factor for cholangiocarcinoma显示文摘 | Sithithaworn P Yongvanit P Duenngai K | 2014 | J Hepatobiliary Pancreat Sci2014,21,5: | 1 |
| 9 | Angiostrongylus infections in rats and snails in northeast Thailand显示文摘 | Pipitgool V Sithithaworn P Pongmuttasaya P | 1997 | Southeast Asian J Trop Med Pub Health1997,28,: | 1 |
| 10 | Risk factors for cholangiocarcinoma in high-risk area of Thailand: role of lifestyle, diet and methylenetetrahydrofolate reductase polymorphisms显示文摘 | Songserm N Promthet S Sithithaworn P | 2012 | Cancer Epidemiol2012,36,2: | 1 |
| 11 | Angiostrongylus infections in rats and snails in northeast Thailand显示文摘 | Pipitgool V Sithithaworn P Pongmuttasaya P | 1997 | Southeast Asian J Trop Med Pub Health1997,28,: | 1 |
| 12 | A ngiostrongylus cantonensis : experimental study on the susceptibility of apple snails, Pomacea canaliculata compared to Pila polita 显示文摘 | Tesana S Srisawangwong T Sithithaworn P | 2008 | Exp Parasitol2008,118,4: | 1 |
| 13 | Towards im- proved diagnosis of zoonotic trematode infections in Southeast A sia显示文摘 | Johansen MV Sithithaworn P Bergquist R | 2010 | AdvParasitol2010,73,: | 1 |
| 14 | Risk factors for cholangiocarcinoma in high-risk area of Thailand: Role of lifestyle, diet and methylenetetrahydrofolate reductase polymorphisms显示文摘 | Nopparat Songserm Supannee Promthet Paiboon Sithithaworn Chamsai Pientong Tipaya Ekalaksananan Peechanika Chopjitt Donald Maxwell Parkin | 2011 | Cancer Epidemiology2011,,2: | 1 |
| 15 | Human contact influences the foraging behaviour and parasite community in long- tailed macaques 显示文摘 | Wenz-Miicke A Sithithaworn P Petney TN | 2013 | Parasitology2013,140,6: | 1 |
| 16 | Morphology and ultrastructure of the digestive gland of Bithynia siamensis goniomophalus(Prosobranehia:Bithyniidae) and alterations induced by infection with the liver fluke Opisthorchis viverrini(Trematoda:Digenea)显示文摘 | Adam R Pipitgool V Sithithaworn P | 1995 | Parasitol Res1995,81,: | 1 |
| 17 | Epidemiology of Opisthorchis viverrini显示文摘 | Sithithaworn P Haswell-Elkins M | 2003 | Aeta Tropica2003,88,3: | 1 |
| 18 | Spatial and temporal genetic variation of Echinostoma revolutum (Trematoda: Echinostomatidae) from Thailand and the Lao PDR显示文摘 | Weerachai Saijuntha Chairat Tantrawatpan Paiboon Sithithaworn Ross H. Andrews Trevor N. Petney | 2011 | Acta Tropica2011,,2: | 1 |
| 19 | Epidemiology of Opisthorchis viverrini 显示文摘 | Sithithaworn P Haswell-Elkins M | 2003 | Acta Tropica2003,88,3: | 1 |
| 20 | Roles of liver fluke infection as risk factor for cholangiocarcinoma 显示文摘 | Sithithaworn P Yongvanit P Duenngai K | 2014 | J Hepatobiliary Pancreat Sci2014,21,5: | 1 |