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9篇 您的检索式:作者名="Sireesh"
    题名 作者 年代 出处 被引量
1The emerging role of redox-sensitive Nrf2-Keap1 pathway in diabetes显示文摘Bhakkiyalakshmi E Sireesh D Rajaguru P 2014Pharmacol Res2014,,:1
2Use of lightweight ECS as a fill material to control approach embankment settlements显示文摘Sireesh S Anand J Richard W 2010Journal of Materials in Civil Engineering ASCE2010,,6:1
3模型研究的基础上对圆片底部支持土工格室碎石垫层砂由软粘土显示文摘Dash S K Sireesh S Sitharam T G 2003土工织物和土工膜2003,,04:1
4Bearing capacity of circular footing on geocell-sand mattress overlying clay bed with void显示文摘Sireesh S Sitharam T G Dash S K 2009Geotextiles and Geomembranes2009,27,2:1
5圆形基础承载力在土工格室砂床垫上覆粘土床空隙显示文摘Sireesh S Sitharam T G Dash S K 2009土工织物和土工膜2009,,02:1
6Caffeic acid and protocatechuic acid modulate Nrf2 and inhibit Ehrlich ascites carcinomas in mice显示文摘Objective:To assess the nuclear factor-erythroid 2-related factor-2(Nrf2)modulatory effect of caffeic acid and protocatechuic acid and determine the anti-tumor activity of these phenolic compounds against Ehrlich ascites carcinoma growth in mice.Methods:Antioxidant activity of protocatechuic acid and caffeic acid was assessed using ferric reducing antioxidant power(FRAP)and 2,2-diphenyl-1-picrylhydrazyl(DPPH).Nrf2 activation potential of phenolic compounds was tested by quantitative realtime polymerase chain reaction,and luciferase complementation reporter assays.In vivo efficacy was tested using the Ehrlich ascites carcinoma model.Results:FRAP and DPPH radical scavenging assays showed that caffeic acid and protocatechuic acid were more potent compared with cinnamic acid and benzoic acid.Luciferase complementation reporter assays identified caffeic acid and protocatechuic acid as the activators of Nrf2.Both caffeic acid and protocatechuic acid upregulated the expression of Nrf2 target genes heme oxygenase-1(HO-1),glutamate-cysteine ligase catalytic subunit(GCLC),and glutamate-cysteine ligase modifier subunit(GCLM)and the activity of NAD(P)H:quinone oxidoreductase 1(NQO1)when tested on HCT-116 cells using a cell-based assay system at 9 h.In addition,intraperitoneal administration of caffeic acid and protocatechuic acid to Ehrlich ascites carcinoma bearing mice suppressed tumor growth and angiogenesis.Conclusions:Caffeic acid and protocatechuic acid can modulate Nrf2 and inhibit Ehrlich ascites carcinoma cells.Venugopal R.Bovilla Preethi G.Anantharaju Sireesh Dornadula Prashanthkumar M.Veeresh Mahadevaswamy G.Kuruburu Vidya G.Bettada Kunka Mohanram Ramkumar SubbaRao V.Madhunapantula 2021Asian Pacific Journal of Tropical Biomedicine2021,11,6:1
7Bearing capacity of circular footing on geocell–sand mattress overlying clay bed with void显示文摘S. Sireesh T.G. Sitharam Sujit Kumar Dash 2008Geotextiles and Geomembranes2008,,2:1
8Model Studies on Circular Footing Supported on Geocell Reinforced Sand Underlain by Soft Clay 显示文摘DASH S K SIREESH S SITHARAM T G 2003Geotextiles and Geomembranes2003,,21:1
9Bearing capacity ofcircular footing on geocell-sand mattress overlying clay bed with void 显示文摘SIREESH S SITHARAM T G DASH S K 2009Geotextiles and Geomembranes2009,27,2:1
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