|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prospective evaluation of small bowel preparation with bisacodyl and sodium phosphate for capsule endoscopy显示文摘AIM: To determine the effect of Prepacol?, a com- bination of sodium phosphate and bisacodyl, on transit and quality of capsule endoscopy (CE). METHODS: Fivety two consecutive patients were included in this prospective study. CE was performed following a 12 h fasting period. Twenty six patients were randomized for additional preparation with Prepacol?. The quality of CE was assessed separately for the proximal and the distal small bowel by 3 experienced endoscopists on the basis of a graduation which was initially developed with 20 previous CE. RESULTS: Preparation with Prepacol? accelerated small bowel transit time (262 ± 55 min vs 287 ± 97 min), but had no effect on the quality of CE. Visibility was significantly reduced in the distal compared to the proximal small bowel. CONCLUSION: The significantly reduced visibility of CE in the distal small bowel allocates the need for a good preparation. Since Prepacol? has no beneficial effect on CE the modality of preparation and the ideal time of application remains unclear. Further standardized examinations are necessary to identify sufficient preparation procedures and to determine the impact of the volume of the preparation solution. | Andreas Franke Frank Hummel Phillip Knebel Christoph Antoni Ulrich Bcker Manfred V Singer Matthias Lhr | 2008 | World Journal of Gastroenterology2008，14，13： | 5 |
| 2 | Enhanced expression of interleukin-18 in serum and pancreas of patients with chronic pancreatitis显示文摘AIM: To investigate interleukin-18 (IL-18) in patients with chronic panreatitis (CP). METHODS: We studied 29 patients with CP and 30 healthy controls. Peripheral blood mononuclear cells (PBMC) were isolated and incubated with 50 mmol/L ethanol, lipopolysaccharide (LPS) (doses 25 g/L, 250 g/L, 2500 g/L) and both agents for 24 h. Levels of IL-18 in the supernatants, and levels of IL-18, IL-12, interferon (IFN)-γ and soluble CD14 in the serum were analysed by ELISA technique. Expression of IL-18 in PBMC was investigated by reverse-transcription (RT)-PCR. IL-18 protein levels in CP tissue and in normal pancreas were studied by ELISA technique. IL-18 levels in PBMC and pancreatic tissue were determined by Westernblot. Im-munohistochemistry for pancreatic IL-18 expression was performed. RESULTS: In patients, IL-18 serum levels were signifi-cantly enhanced by 76% (mean: 289.9 ± 167.7 ng/L) compared with controls (mean: 165.2 ± 43.6 ng/L; P < 0.0005). IL-12 levels were enhanced by 25% in patients (18.3 ± 7.3 ng/L) compared with controls (14.7 ± 6.8ng/L, P = 0.0576) although not reaching the statistical significance. IFN-γ and soluble CD14 levels were not in-creased. In vitro, LPS stimulated significantly and dose-dependently IL-18 secretion from PBMC. Incubation with ethanol reduced LPS-stimulated IL-18 secretion by about 50%. The mRNA expression of IL-18 in PBMC and the response of PBMC to ethanol and LPS was similar in CP patients and controls. In PBMC, no significant differences in IL-18 protein levels were detected between patients and controls. IL-18 protein levels were increased in CP tissues compared to normal pancreatic tissues. IL-18 was expressed by pancreatic acinar cells and by infiltrating inflammatory cells within the pancreas. CONCLUSION: IL-18 originates from the chronically inflammed pancreas and appears to be involved in the fibrotic destruction of the organ. | Alexander Schneider Stephan L Haas Ralf Hildenbrand Sren Siegmund Iris Reinhard Helmut Nakovics Manfred V Singer Peter Feick | 2006 | World Journal of Gastroenterology2006，12，40： | 4 |
| 3 | Wear behavior of triode-sputtered MoS2 coatings in dry sliding contact with steel and ceramics 显示文摘 | Singer I L Fayulle S | 1996 | Wear1996，195，3： | 1 |
| 4 | Determinants of portfolio performance Ⅱ: An update 显示文摘 | BRINSON G P SINGER B D GILBERT L BEE- BOWER G L | 1991 | Financial Analysis Journal1991，47，3： | 1 |
| 5 | Reducing multiclass to binary:a unifying approach for margin classifiers 显示文摘 | Allwein E L Schapire R E Singer Y | 2001 | The Journal of Machine Learning Research2001，1，： | 1 |
| 6 | An analysis of potential risk factors for early complications from fiberoptic bronchoscopy in lung transplant recipients显示文摘 | Smith L Singer JP Hayes M | 2012 | Transpl Int2012，25，2： | 1 |
| 7 | A comparison of methods used in root canal sealability studies显示文摘 | Jensen JR Singer L | 1982 | Oral Surg Oral Med Oral Pathol1982，53，2： | 1 |
| 8 | Acid diffusion analysis of different forms of fluoride in human dental plaque显示文摘 | Ophaug RH Jenkins GN Singer L | 1987 | Arch Oral Biol1987，32，7： | 1 |
| 9 | Indoor pollutants emitted by office equipment: A review of re- ported data and information needs 显示文摘 | Destaillats H Maddalena R L Singer B C | 2008 | Atmospheric Environment2008，42，7： | 1 |
| 10 | Comparison of ketamine- xylazine and ketamine-dexmedetomidine anesthesia and intraperitonea I tolerance in rats显示文摘 | Wellington D Mikaelian I Singer L | 2013 | J Am Assoc Lab Anim Sci2013，52，4： | 1 |
| 11 | Health Insurance and Catastrophic Illness: A Report on the New Cooperative Medical System in Rural China 显示文摘 | Yi H Zhang L Singer K | 2009 | Health Economics2009，18，2： | 1 |
| 12 | Wear behavior of triode-sputtered MoS2 coatings in dry sliding contact with steel and ceramics显示文摘 | Singer I L Fayulle S | 1996 | Wear1996，195，3： | 1 |
| 13 | Chlorination of humicmaterials: byproduct formation and chemical interpretations 显示文摘 | Reckhow D A Singer P C Malcolm R L | 1990 | Environmental Science and Technology1990，24，： | 1 |
| 14 | Neutrophil gelatinase- associated lipocalin: pathophysiology and clinical applica- tions显示文摘 | Cardio - re- conference of Eur Heart J Singer E Marko L Paragas N | 2013 | Acta Physiol (Oxf)2013，207，4： | 1 |
| 15 | The sleep disorders invcnroty an instrument for studiees of sleep disturbancc in persons with Alzheimets disease 显示文摘 | TRACTEN BENG R E SINGER C M CUMMINGS J L | 2003 | J Sleep Res2003，12，4： | 1 |
| 16 | Human papillomavirus detection for cervical cancer prevention with polymerase chain reaction in self-collected samples显示文摘 | Lorenzato FR Singer A Ho L | 2002 | Am J Obstet Gynecol2002，186，： | 1 |
| 17 | Germination requirements of a perennial Alysicarpus vaginalis accession 显示文摘 | Singer K L Pitaman W D | 1988 | Agronomy journal1988，80，6： | 1 |
| 18 | An endothelial ligand for L - selection is a novel mucin - like molecule 显示文摘 | LASKY L A SINGER M S DOWBENKO D | 1992 | Cell1992，69，： | 1 |
| 19 | DBP formation kinetics in a simulated distribution system显示文摘 | BROWN R A SINGER P C | 2001 | Water Research2001，35，14： | 1 |
| 20 | X-ray diffraction of MoS2 coatings prepared byion-beam-assisted deposition显示文摘 | L E Seitzman R N Bolster I L Singer | 1992 | Surf Coat Technol1992，52，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员