|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients显示文摘AIM: To simultaneously evaluate the presence of defects in gallbladder and gastric emptying, as well as in intestinal transit in gallstone patients (GS) and the effect of chronic ursodeoxycholic acid (UDCA) administration on these parameters and on serum bile acids and clinical outcome in GS and controls (CTR). METHODS: After a standard liquid test meal, gallbla-dder and gastric emptying (by ultrasound), oroileal transit time (OITT) (by an immunoenzymatic technique) and serum bile acids (by HPLC) were evaluated before and after 3 mo of UDCA (12 mg/kg bw/d) or placebo administration in 10 symptomatic GS and 10 matched healthy CTR. RESULTS: OITT was longer in GS than in CTR (P < 0.0001); UDCA significantly reduced OITT in GS (P < 0.0001), but not in CTR. GS had longer gastric half-emptying time (t1/2) than CTR (P < 0.0044) at baseline; after UDCA, t1/2 significantly decreased (P < 0.006) in GS but not in CTR. Placebo administration had no effect on gastric emptying and intestinal transit in both GS and CTR. CONCLUSION: The gallstone patient has simultaneous multiple impairments of gallbladder and gastric emptying, as well as of intestinal transit. UDCA administration restores these defects in GS, without any effect in CTR. These results confirm the pathogenetic role of gastrointestinal motility in gallstone disease and suggest an additional mechanism of action for UDCA in reducing bile cholesterol supersaturation. | A Colecchia G Mazzella L Sandri F Azzaroli M Magliuolo P Simoni ML Bacchi-Reggiani E Roda D Festi | 2006 | World Journal of Gastroenterology2006，12，33： | 4 |
| 2 | Visual rating scales for age-related white matter changes (leukoaraiosis): can the heterogeneity be reduced? 显示文摘 | Pantoni L Simoni M Pracucci G | 2002 | Stroke2002，33，12： | 1 |
| 3 | An improved procedure for 2D unstructured Delaunay mesh generation显示文摘 | Secchi S Simoni L | 2003 | Advances in Engineering Software2003，34，4： | 1 |
| 4 | A general multi-stress life model for insulation materials with or without evidence for thresholds显示文摘 | Simoni L Mazzanti G | 1993 | IEEE Trans on El Ins1993，16，3： | 1 |
| 5 | Midlife respiratory function related to white matter lesions and lacunar infarcts in late life显示文摘 | Guo XX Pantoni L Simoni M | 2006 | Stroke2006，37，： | 1 |
| 6 | Progress in electrothermal life modeling of electrical insulation during the last decades显示文摘 | Montanari G C Mzanti G Simoni L A | 2002 | IEEE Transactions on Dielectrics and Electrical Insulation2002，9，5： | 1 |
| 7 | Meganreter: classification, pathophysiology and management显示文摘 | SIMONI F VINO L PIZZINI C | 2000 | Pediatr Med Chir2000，22，： | 1 |
| 8 | STM study of a grain boundary in graphite显示文摘 | SIMONIS P GOFFAUX C THIRY P A BIRO L P LAMBIN P H MEUNIER V | 2002 | Surface Science2002，511，13： | 1 |
| 9 | Progress in Electrothermal Life Modeling of Electrical Insulation during the Last Decades显示文摘 | Montanari G C Mazzanti G Simoni L | 2002 | IEEE Transactions on Dielectrics and Electrical Insulation2002，9，5： | 1 |
| 10 | EAA/EMQN best practice guidelines for molecular diagnosis of Y chromosomal microdeletions:state-of-the-art 2013显示文摘 | KRAUSZ C HOEFSLOOT L SIMONI M | 2014 | Andrology2014，2，1： | 1 |
| 11 | Conjugated Polyene Fatty Acids as Fluorescent Probes:Binding to Bovine Serum Albumin显示文摘 | Sklar L A Hudson B S Simoni R D | 1977 | Biochemistry1977，16，23： | 1 |
| 12 | Megaureter: classification, pathophysiology, and management 显示文摘 | Simoni F Vino L Pizzini C | 2000 | Pediatr Med Chit2000，22，1： | 1 |
| 13 | EAA/EMQN best practice guidelines for molecular diagnosis of Y-chro- mosomal microdeletions : state-of-the-art 2013 显示文摘 | Krausz C Hoefsloot L Simoni M | 2014 | An- drology2014，，1： | 1 |
| 14 | Blood pressure components and changes in relation to white matter lesions: a 32-year prospective population study显示文摘 | Guo X Pantoni L Simoni M | 2009 | Hypertension2009，54，1： | 1 |
| 15 | Changes in autonomic and EEG patterns induced by hypnotic imagination of aversive stimuli in man显示文摘 | Gemignani A Santarcangelo EL Sebastiani L Marchese C Mammoliti R Simoni A Ghelarducci B | 2000 | Brain Res Bull2000，53，： | 1 |
| 16 | Regulatory role of NKT cells in the prevention of type 1 diabetes显示文摘 | Ghazarian L Simoni Y Pingris K | 2013 | Med Sci (Paris)2013，29，89： | 1 |
| 17 | Age-and sex-specific rates of leukoaraiosis in TIA and stroke patients:population-based study显示文摘 | Simoni M Li L Paul NL | 2012 | Neurology2012，79，12： | 1 |
| 18 | Conjugated polyene fatty acids as fluorescent probes:synthetic phospholipid membrane studies显示文摘 | Sklar L A Hudson R D Simoni R D | 1977 | Biochemistry1977，16，5： | 1 |
| 19 | Therapeutic manipulation of natu- ral killer (NK) T cells in autoimmunity: are we close to reality? 显示文摘 | Simoni Y Diana J Ghazarian L | 2013 | Clin Exp Immunol2013，171，1： | 1 |
| 20 | Effects of poly-morphisms in gonadotropin and gonadotropin re-ceptor genes on reproductive function 显示文摘 | Casarini L Pignatti E Simoni M | 2011 | Rev En-docr Metab Disord2011，12，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员