|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients显示文摘AIM: To simultaneously evaluate the presence of defects in gallbladder and gastric emptying, as well as in intestinal transit in gallstone patients (GS) and the effect of chronic ursodeoxycholic acid (UDCA) administration on these parameters and on serum bile acids and clinical outcome in GS and controls (CTR). METHODS: After a standard liquid test meal, gallbla-dder and gastric emptying (by ultrasound), oroileal transit time (OITT) (by an immunoenzymatic technique) and serum bile acids (by HPLC) were evaluated before and after 3 mo of UDCA (12 mg/kg bw/d) or placebo administration in 10 symptomatic GS and 10 matched healthy CTR. RESULTS: OITT was longer in GS than in CTR (P < 0.0001); UDCA significantly reduced OITT in GS (P < 0.0001), but not in CTR. GS had longer gastric half-emptying time (t1/2) than CTR (P < 0.0044) at baseline; after UDCA, t1/2 significantly decreased (P < 0.006) in GS but not in CTR. Placebo administration had no effect on gastric emptying and intestinal transit in both GS and CTR. CONCLUSION: The gallstone patient has simultaneous multiple impairments of gallbladder and gastric emptying, as well as of intestinal transit. UDCA administration restores these defects in GS, without any effect in CTR. These results confirm the pathogenetic role of gastrointestinal motility in gallstone disease and suggest an additional mechanism of action for UDCA in reducing bile cholesterol supersaturation. | A Colecchia G Mazzella L Sandri F Azzaroli M Magliuolo P Simoni ML Bacchi-Reggiani E Roda D Festi | 2006 | World Journal of Gastroenterology2006，12，33： | 4 |
| 2 | Indoor air pollution and air-way disease显示文摘 | Viegi G Simoni M Scogamiglio A | | 0，，12： | 1 |
| 3 | Population-based study of capsular warning syndrome and prognosis after early recurrent TIA显示文摘 | Paul NL Simoni M Chandratheva A | 2012 | Neurology2012，79，13： | 1 |
| 4 | Methanolysis of soybean oil in the presence of tin ( IV ) complexes 显示文摘 | Davi A C Ferreira Mario R Meneghett Simoni M P Me- neghetti | 2007 | Applied Catalysis A : General2007，317，1： | 1 |
| 5 | Nonleaded brass a summary of performance and costs显示文摘 | Sandvig A M Simoni T Edwards M | 2009 | Journal AWWA2009，101，7： | 1 |
| 6 | Penicillin detection by means of field-effect based sensors: EnFET, capacitive EIS sensor or LAPS 显示文摘 | Poghossian A Yoshinobu T Simonis A | 2001 | Sensors and Actuators B2001，，78： | 1 |
| 7 | Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury显示文摘 | Helmy A De Simoni MG Guilfoyle MR | 2011 | Prog Neurobiol2011，95，3： | 1 |
| 8 | Progress in electrothermal life modeling of electrical insulation during the last decades显示文摘 | Montanari G C Mzanti G Simoni L A | 2002 | IEEE Transactions on Dielectrics and Electrical Insulation2002，9，5： | 1 |
| 9 | STM study of a grain boundary in graphite显示文摘 | SIMONIS P GOFFAUX C THIRY P A BIRO L P LAMBIN P H MEUNIER V | 2002 | Surface Science2002，511，13： | 1 |
| 10 | Maintenance of spermatogenesis in hypogonadotropic hypogonadal men with human chorionic gonadotropin alone 显示文摘 | DEPENBUSCH M ECKARDSTEIN S SIMONI M et a! | 2002 | Em J Endocrinol2002，147，5： | 1 |
| 11 | Flavonol monoglycosides isolated from the antiviral fractions of Persea americana (Lauraceae) leaf infusion 显示文摘 | De Almeida A P Miranda M M F S Simoni I C | 1998 | PhytotherRes1998，12，8： | 1 |
| 12 | Population-based study of capsular warning syndrome and prognosis after early recurrent TIA显示文摘 | Paul NL Simoni M Chandratheva A | 2012 | Neurology2012，79，13： | 1 |
| 13 | Prenatal BACson-BeadsTM:a new technology for rapid detection of aneuploidies and microdeletions in prenatal diagnosis显示文摘 | Vialard F Simoni G Aboura A | 2011 | Prenat Diagn2011，31，5： | 1 |
| 14 | Conjugated Polyene Fatty Acids as Fluorescent Probes:Binding to Bovine Serum Albumin显示文摘 | Sklar L A Hudson B S Simoni R D | 1977 | Biochemistry1977，16，23： | 1 |
| 15 | Plaque accumulation on galvano-ceramic crowns显示文摘 | Simonis A Freesmeyer WB Benzing U | 1989 | Dtsch Zahnarztl Z1989，44，： | 1 |
| 16 | Experimental evidences and numerical modeling of debris flows initiated by channel runoff 显示文摘 | Berti M Simoni A M | 2005 | Landslides2005，2，： | 1 |
| 17 | Interpretation of the metabolic enthalpy change,ΔHmet,calculated for microbial growth reactions in soils 显示文摘 | Barros S Feijoo S Simoni A Critter SAM Airoldi C | 2001 | J Therm Anal Calorim2001，63，2： | 1 |
| 18 | Field observations of a debris flow event in the dolomites显示文摘 | Berti M Genevois R Simoni A M | 1999 | Geomorphology1999，29，： | 1 |
| 19 | Population-based study of capsular warning syndrome and prognosis after early recurrent TIA显示文摘 | Paul NL Simoni M Chandratheva A | 2012 | Neurology2012，79，13： | 1 |
| 20 | Prenatal BACs-on-Beads^TM : a new technology for rapid detection of aneuploidies and microdeletions in prenatal diagnosis显示文摘 | Vialard F Simoni G Aboura A | 2011 | Prenat Diagn2011，31，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员