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160篇 您的检索式:作者名="Simoni G"
    题名 作者 年代 出处 被引量
1Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients显示文摘AIM: To simultaneously evaluate the presence of defects in gallbladder and gastric emptying, as well as in intestinal transit in gallstone patients (GS) and the effect of chronic ursodeoxycholic acid (UDCA) administration on these parameters and on serum bile acids and clinical outcome in GS and controls (CTR). METHODS: After a standard liquid test meal, gallbla-dder and gastric emptying (by ultrasound), oroileal transit time (OITT) (by an immunoenzymatic technique) and serum bile acids (by HPLC) were evaluated before and after 3 mo of UDCA (12 mg/kg bw/d) or placebo administration in 10 symptomatic GS and 10 matched healthy CTR. RESULTS: OITT was longer in GS than in CTR (P < 0.0001); UDCA significantly reduced OITT in GS (P < 0.0001), but not in CTR. GS had longer gastric half-emptying time (t1/2) than CTR (P < 0.0044) at baseline; after UDCA, t1/2 significantly decreased (P < 0.006) in GS but not in CTR. Placebo administration had no effect on gastric emptying and intestinal transit in both GS and CTR. CONCLUSION: The gallstone patient has simultaneous multiple impairments of gallbladder and gastric emptying, as well as of intestinal transit. UDCA administration restores these defects in GS, without any effect in CTR. These results confirm the pathogenetic role of gastrointestinal motility in gallstone disease and suggest an additional mechanism of action for UDCA in reducing bile cholesterol supersaturation.A Colecchia G Mazzella L Sandri F Azzaroli M Magliuolo P Simoni ML Bacchi-Reggiani E Roda D Festi 2006World Journal of Gastroenterology2006,12,33:4
2Efficient direct chromosome analyses and enzyme determination from chorinic villi samples in the first trimester of pregnancy 显示文摘Simoni G Brambiti B Denestno C 1983Hum Genet1983,63,4:1
3Visual rating scales for age-related white matter changes (leukoaraiosis): can the heterogeneity be reduced? 显示文摘Pantoni L Simoni M Pracucci G 2002Stroke2002,33,12:1
4Diagnosis application of first trimester trophoblast sampling in 100 pregnancy显示文摘Simoni G Brambiti B Denestno C 1984Hum Genet1984,66,2223:1
5Mcta-analysis of heart valve abnormalities in Parkinson's disease patients treated with do- pamine agonists显示文摘Simonis G Fuhrmann JT Strasser RH 2007Mov Disord2007,22,13:1
6Indoor air pollution and air-way disease显示文摘Viegi G Simoni M Scogamiglio A 0,,12:1
7Eosinophilic inflammation in asthma 显示文摘Bousquet J Chanez P Lacoste JY Barneon G Ghavanian N Enander I Venge P Ahlstedt S Simony - Lafontaine J Godard P 1990N Engl J Med1990,323,:1
8A general multi-stress life model for insulation materials with or without evidence for thresholds显示文摘Simoni L Mazzanti G 1993IEEE Trans on El Ins1993,16,3:1
9Progress in electrothermal life modeling of electrical insulation during the last decades显示文摘Montanari G C Mzanti G Simoni L A 2002IEEE Transactions on Dielectrics and Electrical Insulation2002,9,5:1
10Role of FSH in male gonadal function显示文摘Simoni M Weinbauer G F Gromoll 1999Annales d''Endocrinologie1999,60,:1
11Progress in Electrothermal Life Modeling of Electrical Insulation during the Last Decades显示文摘Montanari G C Mazzanti G Simoni L 2002IEEE Transactions on Dielectrics and Electrical Insulation2002,9,5:1
12Role of FSH in male gonadal function 显示文摘Simoni M Weinbanuer G F Gromoll J 1999Ann Endocrinol (Paris)1999,60,2:1
13Two distinct mechanisms mediate a differential regulation of protein kinase C isozymes in acute and prolonged myocardial ischemia显示文摘STRASSER R H SIMONIS G SCHON S P 1999Circ Res1999,85,1:1
14Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca^2+ waves and protects against Ca2 + -mediated apoptosis显示文摘Szabadkai G Simoni AM Chami M 2004Mol Cell2004,16,1:1
15Prenatal BACson-BeadsTM:a new technology for rapid detection of aneuploidies and microdeletions in prenatal diagnosis显示文摘Vialard F Simoni G Aboura A 2011Prenat Diagn2011,31,5:1
16Regulation of protein kinase C isozymes in volume overload cardiac hypertrophy显示文摘Braun MU LaRosee P Simonis G 2004Mol Cell Biochem2004,262,:1
17Efficient direct chromo- some analyses and enzyme determination from chorionic villi sam- ples in the first trimester of pregnancy显示文摘Simoni G Bramiti B Danesino C 1983Hum Genet1983,63,4:1
18Efficient direct chromosome analyses and enzyme detenrmination from chorionic villi samples in the first trimester of pregnancy显示文摘Simoni G Brambiti B Danesino C 1983Hum Genet1983,63,:1
19Residues of antimicrobial drugs and feed additives in animal products显示文摘Simoni P G Revesado P R Cadahia O 2000Livestock Production Science2000,871,:1
20Prenatal BACs-on-Beads^TM : a new technology for rapid detection of aneuploidies and microdeletions in prenatal diagnosis显示文摘Vialard F Simoni G Aboura A 2011Prenat Diagn2011,31,5:1
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