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9篇 您的检索式:作者名="Simone Co"
    题名 作者 年代 出处 被引量
1血浆游离DNA水平增高可作为预测重型颅脑损伤患者死亡率的独立指标(英文)显示文摘Trauma is the leading cause of death under 45 years worldwide and up to 50% of trauma fatalities are due to brain injury.Prediction of outcome is one of the major problems associated with severe TBI and research efforts have focused on the investigation of biomarkers with prognostic value following TBI. Therefore,our aim was to investigate whether cell-free DNA concentrations correlated to short-term primary outcome( survivor or death) and GCS scores following severe TBI. A total of 188 victims of severe TBI were enrolled in this prospective study,outcome variables comprised: survival and neurological assessment using the GCS at ICU discharge. Control blood samples were obtained from 25 healthy volunteers. Peripheral venous blood was collected at admission in the ICU. Plasma DNA was measured using a real-time quantitative PCR assay for the β-globin gene. There was correlation between higher DNA levels and both fatal outcome and lower hospital admission GCS scores. Plasma DNA concentrations at the chosen cut- off point( ≥171,381 kilogenomesequivalents /L) predicted mortality with a specificity of 90% and a sensitivity of 43%. Logistic regression analysis showed that elevated plasma DNA levels were independently associated with death( P < 0. 001). In conclusion,high cell-free DNA concentration was a predictor of short-term mortality following severe TBI.Rodrigues Filho EM1 Simon D Ikuta N Klovan C Dannebrock F de Oliveira CO Regner A 2014中华神经外科疾病研究杂志2014,13,3:6
2Morning Blood Pressure Surge as a Destabilizing Factor of Atherosclerotic Plaque: Role of Ubiquitin–Proteasome Activity显示文摘Raffaele Marfella Mario Siniscalchi Michele Portoghese Clara Di Filippo Franca Ferraraccio Concetta Schiattarella Basilio Crescenzi Paolo Sangiuolo Giuseppe Ferraro Silvio Siciliano Francesca Cinone Gennaro Mazzarella Simone Martis Mario Verza Ludovico Co 2007Hypertension2007,,4:2
3Theoretical and experimental characterization of transient electromagnetic fields radiated by electromagnetic fields radiated by electrostatic discharge (ESD) currents显示文摘Graziano C Simona Ch Simone Co 2002IEEE Trans on Electromagnetic Compatibility2002,44,1:1
4Exposure to house dust mite allergons and the clinical activity of asthma显示文摘Cdnan Custovic MD Simon CO Taggart 1996J Allery Clin Immunol1996,98,1:1
5CT diagnosis of hepatic aden oma显示文摘Lunong M Simon C Dewery Co 1987Europ J Radiol1987,7,:1
6Using a CONSTRUCTIVIST APPROACH WITH Online Concept Maps:Relationship Between Theory AND Nursing Education显示文摘Concei(co)o Simone C O Taylor Linda D 0,,05:1
7The Anatomy of the Creative City 显示文摘CO HENDET SIMON 2010Industry and Innovation2010,,17:1
8Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis 显示文摘Mega JL Simon T Co/let JP 2010JAMA2010,304,16:1
9Comparison of 2- and 3-Dimensional Shoulder Ultrasound to Magnetic Resonance Imaging in a Community Hospital for the Detection of Supraspinatus Rotator Cuff Tears with Improved Worktime Room Efficiency显示文摘Steven Co Sonny Bhalla Kevin Rowan Sven Aippersbach Simon Bicknell 2012Canadian Association of Radiologists Journal2012,,3:1
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