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| 1 | Metastatic type 1 gastric carcinoid:A real threat or just a myth?显示文摘AIM:To describe disease characteristics and treatment modalities in a group of rare patients with metastatic gastric carcinoid type 1(GCA1).METHODS:Information on clinical,biochemical,radiological,histopathological findings,the extent of the disease,as well as the use of different therapeutic modalities and the long-term outcome were recorded.Patients’data were assessed at presentation,and thereafter at 6 to 12 monthly intervals both clinically and biochemically,but also endoscopically and histopathologically.Patients were evaluated for the presence of specific symptoms;the presence of autoimmune disorders and the presence of other gastrointestinal malignancies in other family members were also recorded.The evaluation of response to treatment was defined using established WHO criteria.RESULTS:We studied twenty consecutive patients with a mean age of 55.1 years.The mean follow-up period was 83 mo.Twelve patients had regional lymph node metastases and 8 patients had liver metastases.The primary tumor mean diameter was 20.13±10.83mm(mean±SD).The mean Ki-67 index was 6.8%±11.2%.All but one patient underwent endoscopic or surgical excision of the tumor.The disease was stable in all but 3 patients who had progressive liver disease.All patients remained alive during the follow-up period.CONCLUSION:Metastatic GCA1 carries a good overall prognosis,being related to a tumor size of≥1 cm,an elevated Ki-67 index and high serum gastrin levels. | Simona Grozinsky-Glasberg Dimitrios Thomas Jonathan R Strosberg Ulrich-Frank Pape Stephan Felder Apostolos V Tsolakis Krystallenia I Alexandraki Merav Fraenkel Leonard Saiegh Petachia Reissman Gregory Kaltsas David J Gross | 2013 | World Journal of Gastroenterology2013，19，46： | 11 |
| 2 | The Structure and Evolution of Industrial Clusters:Transactions,Technology and Knowledge Spillovers显示文摘 | Simona I Philip M C | 2006 | Research Policy2006，，35： | 1 |
| 3 | HPLC fingerprint of bioactive compounds and antioxidant activities of Viscum album from differ-ent host trees显示文摘 | SIMONA I V DUMITRIA RA LOREDANA L | 2011 | Not Bot Hort Agrobot Cluj2011，39，1： | 1 |
| 4 | Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes 显示文摘 | Rodrigo M Simona I Ronald B | 2006 | Blood2006，108，： | 1 |
| 5 | The structure and evolution of industrial clusters: Transactions, technology and knowl- edge spillovers显示文摘 | Simona I Philip M C | 2006 | Research Policy2006，，35： | 1 |
| 6 | The structure and evolution of industrial clusters:transactions,technology and knowledge spillovers显示文摘 | Simona I Philip M C | 2006 | Research Policy2006，35，7： | 1 |
| 7 | Characterizing polyester fabrics treated in electrical discharges of radio-frequency plasma显示文摘 | Ioan I Negulescu Simona Despa Jormthan Chen | 2000 | TRJ2000，70，1： | 1 |
| 8 | Rituximab treatment in a patient with severe thyroid-associated ophthalmopathy :effects on orbital lymphocytic infiltrates 显示文摘 | Salvi M Vannucchi G Campi I Currb N Simona S Covelli D | 2009 | Clin Immuno12009，131，2： | 1 |
| 9 | Analytical and numerical approach for tunnel face advance in a viscoplastic rock mass显示文摘 | Simona Roate?i | 2014 | International Journal of Rock Mechanics and Mining Sciences2014，，： | 1 |
| 10 | Breast cancer: role of SPECT and PET in imag- ing bone metastases显示文摘 | Simona BH Ora I | 2009 | Semin Nucl Med2009，39，6： | 1 |
| 11 | Clinical outcome of aortic valve replacement in the elderly 显示文摘 | BRUNO C MARCELLO B SIMONA G I | 2003 | Cardiovascular Surgery2003，5，： | 1 |
| 12 | Pain and oxidative stress in the newborn显示文摘 | iLorenzo I Carlo V B Simona N | 2010 | Early Hum Dev2010，86，1： | 1 |
| 13 | The structure and evolution of industrial clusters: Transactions, technology and knowledge spillovers 显示文摘 | SIMONA I PHILIP M | 2006 | Research policy2006，，7： | 1 |
| 14 | The competition between acetate and pyrazolate in the forma- tion of polynuclear Zn(Ⅱ ) coordination complexes显示文摘 | AUGUSTO C I SIMONA G NORBERTO M | 2006 | Dalton Transactions2006，20，： | 1 |
| 15 | In vitro hepatic ditlerentiation of human bone marrow mesenchymal stem cells under differential exposure to liver-specific factors显示文摘 | Mihaela C Simona O D Cosmin I S | 2009 | Translat Res2009，154，3： | 1 |
| 16 | In vitro hepatic differentiation ofhuman bonemarrowmesenchymal stem cells under differential exposure to liver-specific factors显示文摘 | Mihaela C Simona O D Cosmin I S | 2009 | Translational Research2009，154，1： | 1 |
| 17 | Retrospectivecomparison of reduced- intensity conditioning and conventionalhigh- dose conditioning for allogeneic hematopoietic stem celltransplantation using HLA-identical sibling donors in myelo-dysplastic syndromes显示文摘 | RODRIGO M SIMONA I RONALD B | 2006 | Blood2006，108，： | 1 |
| 18 | Copper electrodeposition from sulfate electrolytes in the presence of hydroxyethylated 2 - butyne - 1,4 - diol显示文摘 | Simona Varvara Liana Muresan Popescu I C | 2004 | Hydrometallurgy2004，75，： | 1 |
| 19 | An integrated and cooperative architecture for multi-intersection traffic signal control显示文摘Traffic signal control(TSC)systems are one essential component in intelligent transport systems.However,relevant studies are usually independent of the urban traffic simulation environment,collaborative TSC algorithms and traffic signal communication.In this paper,we propose(1)an integrated and cooperative Internet-of-Things architecture,namely General City Traffic Computing System(GCTCS),which simultaneously leverages an urban traffic simulation environment,TSC algorithms,and traffic signal communication;and(2)a general multi-agent reinforcement learning algorithm,namely General-MARL,considering cooperation and communication between traffic lights for multi-intersection TSC.In experiments,we demonstrate that the integrated and cooperative architecture of GCTCS is much closer to the real-life traffic environment.The General-MARL increases the average movement speed of vehicles in traffic by 23.2%while decreases the network latency by 11.7%. | Qiang Wu Jianqing Wu Bojian Kang Bo Du Jun Shen Adriana Simona Mihăiţă | 2023 | Digital Transportation and Safety2023，2，2： | 0 |
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