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| 1 | Promoting physical activity and a healthful diet among children: results of a school-based intervention study显示文摘 | Bruce G Simons M Guy SP | 1999 | Am J Public Health1999，81，： | 1 |
| 2 | A role for Wnt 4 in renal fi- brosis显示文摘 | Surendran K McCaul SP Simon TC | 2002 | Am J Physiol Renal Physiol2002，282，3： | 1 |
| 3 | A small mole- cule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage显示文摘 | Simone TM Higgins SP Archambeault J | 2015 | Cell Signal2015，27，5： | 1 |
| 4 | Bon e miner al density,carotid artery intima-media thickness,and Klotho gene polymorphism in postmenopausal women显示文摘 | Munte an L Simon SP Po pp R | 2014 | Cent Eur J Medi2014，9，2： | 1 |
| 5 | Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2on bone regeneration in a rat critical-size defect model显示文摘 | Simon Y Zarana SP James DK | | 0，，09： | 1 |
| 6 | A role for Wnt-4 in renal fibrosis显示文摘 | Surendran K McCaul SP Simon TC | 2002 | Am J Physiol Renal Physiol2002，282，3： | 1 |
| 7 | A role for Writ4 in renal fibrosis 显示文摘 | Surendran K McCaul SP Simon TC | 2002 | Am J Physic Renal Physiol2002，282，3： | 1 |
| 8 | Functional living trileaflet heart valves grown in vitro 显示文摘 | Simon P Hoerstrup SP Sodian R | 2000 | Circulation2000，102，： | 1 |
| 9 | Assisted venous drainage, venous air, and gaseous microemboli transmission onto the arterial line: an in-vitro study显示文摘 | Simon LV Rice BJ | 1998 | J Extra Corpor Technol1998，30，4： | 1 |
| 10 | A role for Wnt4 in renal fibrosis显示文摘 | SURENDRAN K MCCAUL SP SIMON TC | 2002 | Am J Physiol Renal Physiol2002，282，3： | 1 |
| 11 | A role for Wnt-4 in renal fibrosis显示文摘 | Surendran K McCaul SP Simon TC | 2002 | Am J Physiol Renal Physiol2002，282，3： | 1 |
| 12 | A role for Wnt4 in renal fibrosis显示文摘 | Surendran K McCaul SP Simon TC | 2002 | AmJ Physiol Renal Physiol2002，282，3： | 1 |
| 13 | A role for Wnt-4 in renal fibrosis显示文摘 | Surendran K Mc Caul SP Simon TC | 2002 | Am J Physiol Renal Physiol2002，282，3： | 1 |
| 14 | Chemical an- tagonists of plasminogen activator inhibitor-1 : mechanisms of action and therapeutic potential in vascular disease显示文摘 | Simone TM Higgins SP Higgins CE | 2014 | J Mol Genet Med2014，8，： | 1 |
| 15 | Pulmonary veins: anatomy, electrophysiology, tachycardia, and fibrillation显示文摘 | Fynn SP Simon P Kalman JM | 2004 | Pacing Clini Electrophysiol2004，27，11： | 1 |
| 16 | Use of hybrid chitosan membranes and human mesenchymal stem cells from the Wharton jelly of umbilical cord for promoting nerve regeneration in an axonotmesis rat model显示文摘Many studies have been dedicated to the development of scaffolds for improving post-traumatic nerve regeneration. The goal of this study was to assess the effect on nerve regeneration, associating a hybrid chitosan membrane with non-differentiated human mesenchymal stem cells isolated from Wharton's jelly of umbilical cord, in peripheral nerve reconstruction after crush injury. Chromosome analysis on human mesenchymal stem cell line from Wharton's jelly was carried out and no structural alterations were found in metaphase. Chitosan membranes were previously tested in vitro, to assess their ability in supporting human mesenchymal stem cell survival, expansion, and differentiation. For the in vivo testing, Sasco Sprague adult rats were divided in 4 groups of 6 or 7 animals each:Group 1, sciatic axonotmesis injury without any other intervention (Group 1-Crush); Group 2, the axonotmesis lesion of 3 mm was infiltrated with a suspension of 1 250-1 500 human mesenchymal stem cells (total volume of 50 μL) (Group 2-CrushCell); Group 3, axonotmesis lesion of 3 mm was enwrapped with a chitosan type III membrane covered with a monolayer of non-differentiated human mesenchymal stem cells (Group 3-CrushChitIIICell) and Group 4, axonotmesis lesion of 3 mm was enwrapped with a chitosan type III membrane (Group 4-CrushChitIII). Motor and sensory functional recovery was evaluated throughout a healing period of 12 weeks using sciatic functional index, static sciatic index, extensor postural thrust, and withdrawal reflex latency. Stereological analysis was carried out on regenerated nerve fibers. Results showed that infiltration of human mesenchymal stem cells, or the combination of chitosan membrane enwrapment and human mesenchymal stem cell enrichment after nerve crush injury provide a slight advantage to post-traumatic nerve regeneration. Results obtained with chitosan type III membrane alone confirmed that they significantly improve post-traumatic axonal regrowth and may represent a very promising clinical tool in peripheral nerve reconstructive surgery. Yet, umbilical cord human mesenchymal stem cells, that can be expanded in culture and induced toform several different types of cells, may prove, in future experiments, to be a new source of cells for cell therapy, including targets such as peripheral nerve and muscle. | Andrea Gärtner Tiago Pereira Maria Joāo Simōes Paulo AS Armada-da-Silva Miguel L França Rosa Sousa Simone Bompasso Stefania Raimondo Yuki Shirosaki Yuri Nakamura Satoshi Hayakawa Akiyoshi Osakah Beatriz Porto Ana Lúcia Luís Artur SP Varejāo Ana Colette Maurício | 2012 | Neural Regeneration Research2012，7，29： | 1 |
| 17 | A role for wnt-4 in renal fibrosis 显示文摘 | Surendran K Mccaul SP Simon TC | 2002 | Am J Physiol Renal Physio12002，282，3： | 1 |
| 18 | Association of ABO Blood Group and Rh factor with Periodontal Disease in a Population of Virajpet,Karnataka:A Cross-Sectional Study显示文摘 | Vivek S Jain J Simon SP | 2013 | J Int Oral Health2013，5，： | 1 |
| 19 | Tissue engineering of heart valves: in vitro experience 显示文摘 | Simon P Hoerstrup SP | 2000 | Ann Thorac Surg2000，70，： | 1 |
| 20 | A role for Wnt-4 in renal fibrosis显示文摘 | Surendran K McCaul SP Simon TC | 2002 | Am J Physiol Renal Physiol2002，282，： | 1 |
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