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13篇 您的检索式:作者名="Simanainen"
    题名 作者 年代 出处 被引量
1Estradiol induction of spermatogenesis is mediated via an estrogen receptor- falphat mechanism involving neuroendocrine activation of follicle, stimulating hormone secretion 显示文摘ALLAN C M COUSE J F SIMANAINEN U 2010Endocrinology2010,151,:1
2induction of spermatogenesis is mediated via an neuroendoc receptor- t alpha t mechanism involving rine activation of follicle-stimulating hormone secretion 显示文摘ALLAN Estradiol estrogen C M COUSE J F SIMANAINEN U 2010Endocrinology2010,151,:1
3Molecular insights into androgen actions in male and female reproductive function from androgen receptor knockout models显示文摘Walters KA Simanainen U Handelsman DJ 0,,:1
4Molecular insights into androgen actions in male and female reproductive function from androgen receptor knockout models 显示文摘Waiters KA Simanainen U Handelsman DJ 2010Hum Reprod Update2010,16,5:1
5The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on foetal male rat steroido- genesis显示文摘Adamsson A Simanainen U Viluksela M 2009Int J Androl2009,32,5:1
6Estradiol induc- tion of spermatogenesis is mediated via an estrogen reeeptor-a mechanism involving neuroendocrine activation of follicle-stimula- ting hormone secretion 显示文摘ALLAN CM COUSE JF SIMANAINEN U 2010Endocrinology2010,151,6:1
7Adult 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure and effects on male reproductive organs in three differentially TCDD-susceptible rat lines显示文摘Simanainen U Adamsson A Tuomisto JT 2004Toxicol Sci2004,81,2:1
8Molecular insights into androgen actions in male and female repro- ductive function from androgen receptor knockout models 显示文摘Wahers KA Simanainen U Handelsman DJ 2010Hum Reprod Update2010,16,5:1
9Length of the human androgen receptor glutamine tract determines androgen sensitivity in vivo显示文摘Ulla Simanainen Michele Brogley Yan Ru Gao Mark Jimenez D. Tim Harwood David J. Handelsman Diane M. Robins 2011Molecular and Cellular Endocrinology2011,,1:1
10Molecu- lar insights into androgen actions in male and female reproductive function from androgen receptor knockout models显示文摘Walters K A Simanainen U Handelsman D J 2010Hum Reprod Update2010,16,5:1
11Molecular insights into androgen actions in male and female reproductive function from an- drogen receptor knockout models显示文摘Wahers KA Simanainen U Handelsman DJ 2010Hum Reprod Update2010,16,5:1
12Mitochondrial DNA Sequences from Switzerland Reveal Striking Homogeneity of European Populations 显示文摘Pult I Sajantila A Simanainen J 1994Biol Chem Hoppe Sayler1994,375,12:1
13The contradictory role of androgens in cutaneous and major burn wound healing显示文摘Wound healing is a complex process involving four overlapping phases:haemostasis,inflammation,cell recruitment and matrix remodeling.In mouse models,surgical,pharmacological and genetic approaches targeting androgen actions in skin have shown that androgens increase interleukin-6 and tumor necrosis factor-αproduction and reduce wound re-epithelization and matrix deposition,retarding cutaneous wound healing.Similarly,clinical studies have shown that cutaneous wound healing is slower in men compared to women.However,in major burn injury,which triggers not only local wound-healing processes but also systemic hypermetabolism,the role of androgens is poorly understood.Recent studies have claimed that a synthetic androgen,oxandrolone,increases protein synthesis,improves lean body mass and shortens length of hospital stay.However,the possible mechanisms by which oxandrolone regulates major burn injury have not been reported.In this review,we summarize the current findings on the roles of androgens in cutaneous and major burn wound healing,as well as androgens as a potential therapeutic treatment option for patients with major burn injuries.Huaikai Shi Kenny Cheer Ulla Simanainen Brian Lesmana Duncan Ma Jonathan J.Hew Roxanne J.Parungao Zhe Li Mark S.Cooper David J.Handelsman Peter K.Maitz Yiwei Wang 2021Burns & Trauma2021,9,1:0
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