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3篇 您的检索式:作者名="Siddharth Gupta"
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1Engineered nanocrystal technology: In-vivo fate, targeting and applications in drug delivery显示文摘Vivek K. Pawar Yuvraj Singh Jaya Gopal Meher Siddharth Gupta Manish K. Chourasia 2014Journal of Controlled Release2014,,:1
2Stroke in COVID-19: a single-centre initial experience in a hotspot of the pandemic显示文摘Background COVID-19,caused by SARS-CoV-2,is a global pandemic that has been an immense burden on healthcare systems all over the world.These patients may be at higher risk for acute ischaemic stroke(AIS).We present our experience with AIS in patients with COVID-19.Methods We reviewed all patients admitted to our hospital during a 6-week period with a positive nasopharyngeal swab test for SARS-CoV-2.Among these patients,we identified AIS.We reviewed the demographics,clinical,laboratory,imaging characteristics,treatments received and outcomes of AIS in patients with COVID-19.Results We identified 683 patients admitted with COVID-19 during the study period,of which 20 patients had AIS.Large-vessel occlusion(LVO)was noted in 11 patients(55%).Intravenous alteplase was administered in four patients(20%)and mechanical thrombectomy was performed in five patients(25%).Respiratory symptoms preceded the onset of AIS in most of the patients(70%)by 1 to 21 days.Mortality in patients with AIS was 50%compared with 26%of all COVID-19 admissions.Most of these patients died due to non-neurological causes(70%).Three patients with AIS had clinical and imaging findings consistent with COVID-19,but were negative for multiple nasopharyngeal swab tests.Interpretation LVO was more common in patients with AIS and COVID-19.They had more severe disease and higher mortality rates.Most of the patients had respiratory symptoms preceding AIS by days to weeks.This could explain certain patients with clinical picture of COVID-19 but negative nasopharyngeal swab tests.Ivo Bach Pratibha Surathi Nora Montealegre Osama Abu-Hadid Sara Rubenstein Sviatoslav Redko Siddharth Gupta Machteld Hillen Pratit Patel Priyank Khandelwal Adham Kamel 2020Stroke & Vascular Neurology2020,5,4:0
3Composite pheochromocytoma masquerading as solidpseudopapillary neoplasm of pancreas显示文摘Pheochromocytoma and ganglioneuroma form rare composite tumours of the adrenal medulla comprising less than 3% of all sympathoadrenal tumours. We present a case of intraoperatively detected adrenal medullary tumour of composite pheochromocytoma and ganglioneuroma diagnosed on histopathology, in a normotensive patient. A 50-year-old male with a past history of chronic obstructive pulmonary disease presented with abdominal pain and significant weight loss since one month. Ultrasound and contrast-enhanced computed tomography abdomen revealed a large lobulated lesion in the distal body and tail of pancreas suggestive of solid and papillary neoplasm of body and tail of pancreas. Intra-operatively, a 15 cm × 10 cm solid lesion with cystic areas was seen arising from the left lower pole of the adrenal gland pushing the pancreas which appeared unremarkable. In our case, exploratory laparotomy with tumour excision was done. Extensive sectioning and microscopic examination of this adrenal tumour confirmed a diagnosis of composite Pheochromocytoma with Ganglioneuroma on histopathology. Immunophenotyping with S-100 further supported the diagnosis. The goal of this report is to increase the awareness of this rare disease and to further identify its variable presentation.Geetanjali Gupta Ravindra Kumar Saran Satyajit Godhi Siddharth Srivastava Sundeep Singh Saluja Pramod Kumar Mishra 2015World Journal of Clinical Cases2015,3,5:0
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