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| 1 | Long-term precipitation change by hourly data in Haihe River Basin during 1961–2004显示文摘Hourly summer precipitation data recorded at 21 stations during 1961-2004 in the Haihe River Basin in North China were analyzed. The results show that the precipitation frequency and amount and the morning peak mainly relating to long-duration rainfall events decreased during this period, whereas the normalized afternoon peak mainly relating to short-duration events increased, which may suggest that the proportion of short-duration rainfall has increased as the total summer rainfall has decreased. For short-duration events, the mean intensity and peak intensity increased at most stations and the time to peak intensity decreased, which may be attributable to the higher thermal contrast between the warmer lower surface and cooler upper level. In the case of long-duration events, the total amount was significantly correlated with the East Asian summer monsoon index for the period 1961-2001 (correlation coefficient of 0.63). Although the total amount of rainfall in long-duration events decreased in the basin, the mean intensity and peak intensity, as well as the extreme hourly precipitation, increased in the western basin and decreased in the eastern basin. | YIN ShuiQing GAO Ge LI WeiJing CHEN DeLiang HAO LiSheng | 2011 | Science China Earth Sciences2011，54，10： | 12 |
| 2 | Evaluation of Typhoon Waves Simulated by Wave Watch-Ⅲ Model in Shallow Waters Around Zhoushan Islands显示文摘In this study, we simulated typhoon waves in the shallow waters around the Zhoushan Islands using the WaveWatch-Ⅲ(WW3) model version 5.16, the latest version released by the National Oceanic and Atmospheric Administration. Specifically, we used in-situ measurements to evaluate the performance of seven packages of input/dissipation source terms in the WW3 model. We forced the WW3 model by wind fields derived from a combination of the parametric Holland model and high-resolution European Center for Medium-Range Weather Forecasts(ECMWF) wind data in a 0.125? grid, herein called H-E winds. We trained the H-E winds by fitting a shape parameter B to buoy-measured observations, which resulted in a smallest root mean square error(RMSE) of 3 m s^(-1) for B, when treated as a constant 0.4. Then, we applied the seven input/dissipation terms of WW3, labelled ST1, ST2, ST2+STAB2, ST3, ST3+STAB3, ST4, and ST6, to simulate the significant wave height(SWH) up to 5 m during typhoons Fungwong and Chan-hom around the Zhoushan Islands. We then compared the SWHs of the simulated waves with those measured by the in-situ buoys. The results indicate that the simulation using ST2 performs best with an RMSE of 0.79 m for typhoon Fung-wong and an RMSE of 1.12 m for typhoon Chan-hom. Interestingly, we found the simulated SWH results to be relatively higher than those of the observations in the area between Hangzhou Bay and the Zhoushan Islands. This behavior is worthy of further investigation in the future. | SHENG Yexin SHAO Weizeng LI Shuiqing ZHANG Yuming YANG Hongwei ZUO Juncheng | 2019 | Journal of Ocean University of China2019，18，2： | 9 |
| 3 | Comparison of screening strategies for Lynch syndrome in patients with newly diagnosed endometrial cancer:a prospective cohort study in China显示文摘Background: The prevalence of Lynch syndrome and screening strategies for this disorder in Chinese patients with endometrial cancer have seldom been investigated. Such data would be essential for the screening, prevention, genetic counseling, and treatment of Lynch syndrome. The purpose of this prospective study was to determine the accuracy of the mismatch repair (MMR) protein immunohistochemistry (IHC), microsatellite instability (MSI) test, and clinical diagnostic criteria in screening for Lynch syndrome-associated endometrial cancer (LS-EC) in a prospective Chinese cohort. Methods: All patients with newly diagnosed endometrial cancer (EC) were evaluated using clinical diagnostic criteria (Amsterdam II criteria and the revised Bethesda guidelines), MSI test, and IHC of MMR proteins in tumor tissues. For all patients, the screening results were compared with results of germline sequencing for pathogenic variants of MMR genes. Results: Between December 2017 and August 2018, a total of 111 unselected patients with newly diagnosed EC were enrolled. Six patients (5.4%) harbored a pathogenic germline mutation of MMR genes: 1 had a mutation in MutL homolog 1 (MLH1), 2 in MutS homolog 2 (MSH2), and 3 in MutS homolog 6 (MSH6). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for identifying LS-EC were 33.3%, 88.6%, 14.3%, and 95.9%, for the clinical criteria, 66.7%, 75.0%, 14.3%, and 97.3% for IHC of MMR proteins, 100%, 89.9%, 33.3%, and 100% for MSI test, and 100%, 72.4%, 20.0% and 100% for combined IHC and MSI test, respectively. The combination of IHC and MSI test had higher sensitivity and PPV than the clinical criteria (p = 0.030). MSI test and IHC were highly concordant for LS-EC screening (73/77, 94.8%). Conclusion: The accuracy of the combination of IHC of MMR proteins and MSI test for screening LS among Chinese patients with EC was superior to that of the clinical criteria. | Xiaopei Chao Lei Li Ming Wu Shuiqing Ma Xianjie Tan Sen Zhong Yalan Bi Jinghe Lang | 2019 | Cancer Communications2019，39，1： | 8 |
| 4 | V4C3Tx MXene:A promising active substrate for reactive surface modification and the enhanced electrocatalytic oxygen evolution activity显示文摘Presented are the synthesis,characterizations,and reactive surface modification(RSM)of a novel nine atomic layered V4C3Tx MXene.With the advantages of the multilayered V4C3Tx MXene that can simultaneously support the RSM reaction and keep the inner skeleton stable,a series of amorphous Ni/Fe/Vternary oxide hydroxides thin layer can be successfully modified on the surface of the V4C3Tx MXene(denoted as MOOH@V4C3Tx,M=Ni,Fe,and V)without disrupting its original structure.Attributed to the in situ reconstruction of highly active oxide hydroxide layer,the nanohybrids exhibited an enhanced oxygen evolution reaction(OER)activity and excellent long-time stability over 70 hours.In particular,a current density of 10 mA cm−2 can be reached by the nanohybrid with the optimized Ni/Fe ratio at an overpotential(η)as low as 275.2 mV,which is comparable to most of the state-of-the-art OER catalysts and better than other MXene-based derivatives.Demonstrated by the tunable physicochemical properties and excellent structural stability of these nanohybrids,we may envision the promising role of the M4X3-based MXenes as substrates for a wide range of energy conversion and storage materials. | Cheng-Feng Du Xiaoli Sun Hong Yu Wei Fang Yao Jing Yonghui Wang Shuiqing Li Xianhu Liu Qingyu Yan | 2020 | InfoMat2020，2，5： | 8 |
| 5 | NOD-like receptors mediated activation of eosinophils interacting with bronchial epithelial cells: a link between innate immunity and allergic asthma显示文摘对细菌的感染的天生的免疫的关键 intracytosolic 模式识别受体是象受体(NLR ) 一样的核苷酸绑定 oligomerization 领域(点头) 。我们阐明了 NOD1 和人的嗜曙红血球的调停 NOD2 的激活,为过敏发炎的主要受动器房间,在在过敏气喘与人的支气管的上皮的 BEAS-2B 房间交往之上。嗜曙红血球组成地表示了 NOD1,2,但是展出了不重要的回答由 NOD1 ligand γ 在刺激之上释放 chemokines; -D-glutamyl-meso-diaminopimelic 酸(即弹跳) 和 NOD2 ligand muramyl dipeptide (MDP ) 。然而,即弹跳和 MDP 能显著地 CD18 的 upregulate 房间表面表示和细胞间的粘附分子(ICAM ) 嗜曙红血球上的 -1 和 BEAS-2B 房间上的 ICAM-1,以及在 coculture 系统导致 chemokines CCL2 和 CXCL8 版本(所有 P < 0.05 ) 。嗜曙红血球和 BEAS-2B 房间在在即弹跳或 MDP 刺激之上的 coculture 系统是为 CXCL8 和 CCL2 版本的主要来源。在嗜曙红血球和 BEAS-2B 房间之间的直接相互作用为 CCL2 版本负责,并且可溶的调停人在 CXCL8 版本被含有。英皇家空军之阶级最低之兵和 NF-κ B 玩为在 coculture 的粘附分子和 chemokines 的表示的规章的角色。有 NOD1,2 ligand 的处理能导致 subepithelial 纤维变性并且显著地提高全部的 IgE,为嗜曙红血球的 chemokine CCL5 和 T 助手类型的浆液集中 2 (Th2 )在 敏化ovalbumin 的过敏气喘的老鼠的 bronchoalveolar lavage 液体的房间和气喘 Th2 cytokine IL-13 (所有 P < 0.05 )。这研究在经由在煽动性的航线与支气管的上皮的房间交往的嗜曙红血球的激活触发过敏气喘提供 NOD1,2 的细菌的调停感染的激活的进一步的证据。 | Churl Kwok Wong Shuiqing Hu Karen Ming-Lam Leungt Jie Dong Lan He Yi Jun Chu Ida Miu-Ting Chu Huai-Na Qiu Kelly Yan-Ping Liu ChristopherWai-Kei Lam | 2013 | Cellular & Molecular Immunology2013，10，4： | 7 |
| 6 | The comparison of altimeter retrieval algorithms of the wind speed and the wave period显示文摘With the launch of altimeter,much effort has been made to develop algorithms on the wind speed and the wave period.By using a large data set of collocated altimeter and buoy measurements,the typical wind speed and wave period algorithms are validated.Based on theoretical argument and the concept of wave age,a semi-empirical algorithm for the wave period is also proposed,which has the wave-period dimension,and explicitly demonstrates the relationships between the wave period and the other variables.It is found that Ku and C band data should be applied simultaneously in order to improve either wind speed or wave period algorithms.The dual-band algorithms proposed by Chen et al.(2002) for the wind speed and Quilfen et al.(2004) for the wave period perform best in terms of a root mean square error in the practical applications. | ZHAO Dongliang LI Shuiqing SONG Chaoyang | 2012 | Acta Oceanologica Sinica2012，31，3： | 6 |
| 7 | Numerical simulation and preliminary analysis of typhoon waves during three typhoons in the Yellow Sea and East China Sea显示文摘In this study,typhoon waves generated during three typhoons(Damrey(1210),Fung-wong(1416),and Chan-hom(1509))in the Yellow Sea and East China Sea were simulated in a simulating waves nearshore(SWAN)model,and the wind forcing was constructed by combining reanalyzed wind data with a Holland typhoon wind model.Various parameters,such as the Holland fitting parameter(B)and the maximum wind radius?,were investigated in sensitivity experiments in the Holland model that affect the wind field construction.Six different formulations were considered and the parameters determined by comparing the simulated wind results with in-situ wind measurements.The key factors affecting wave growth and dissipation processes from deep to shallow waters were studied,including wind input,whitecapping,and bottom friction.Comparison with in-situ wave measurements suggested that the KOMEN scheme(wind input exponential growth and whitecapping energy dissipation)and the JONSWAP scheme(dissipation of bottom friction)resulted in good reproduction of the significant wave height of typhoon waves.A preliminary analysis of the wave characteristics in terms of wind-sea and swell wave revealed that swell waves dominated with the distance of R to the eye of the typhoon,while wind-sea prevailed in the outer region up to six to eight times the R values despite a clear misalignment between wind and waves.The results support the hypothesis that nonlinear wave-wave interactions may play a key role in the formation of wave characteristics. | WANG Ning HOU Yijun LI Shuiqing LI Rui | 2019 | Journal of Oceanology and Limnology2019，37，6： | 5 |
| 8 | Molecular dynamics simulation and continuum modelling of granular surface flow in rotating drums显示文摘Numerical simulations of granular flows in rotating drums operated at medium to high rates (Fr=0.1― 0.2) have been carried out by using a Molecular Dynamics (MD) algorithm that incorporates inelastic particle interactions, sliding friction and rolling friction. The results indicate that the behavior of granular flow in rotating drums can be classified into two distinct zones: a shear active layer at the bed surface and a quasi-static plug flow region adjacent to the wall. The residence time of a tracer particle in the active layer is approximately a third or a half of that in the plug flow region. The thickness of the active layer at mid-chord is about 0.57―0.61 times that of the plug flow region. It is found that all cases simulated in this work are in the rolling-cascading intermediate regime instead of the pure rolling re-gime. The simulated tangential velocity at the mid-chord is also compared with experimental results reported in the literature and good agreement has been obtained. Based on the MD simulations and experimental results, a continuum approach has also been developed. It is shown that the behavior of granular solids in the plug flow region experiences plastic deformation along the radial direction from the wall with the velocity profiles well described by an exponential function, whereas the active layer velocity follows a simple expression for the Couette shear flow. Discussion has also been made on the granular temperature and concentration profiles. | LI ShuiQing YAO Qiang CHEN Bing ZHANG Xuan DING Y L | 2007 | Chinese Science Bulletin2007，52，5： | 3 |
| 9 | Spirulina platensis aqueous extracts ameliorate colonic mucosal damage and modulate gut microbiota disorder in mice with ulcerative colitis by inhibiting inflammation and oxidative stress显示文摘Ulcerative colitis(UC)is a chronic and recurrent inflammatory bowel disease(IBD)that has become a major gastroenterologic problem during recent decades.Numerous complicating factors are involved in UC development such as oxidative stress,inflammation,and microbiota disorder.These factors exacerbate damage to the intestinal mucosal barrier.Spirulina platensis is a commercial alga with various biological activity that is widely used as a functional ingredient in food and beverage products.However,there have been few studies on the treatment of UC using S.platensis aqueous extracts(SP),and the underlying mechanism of action of SP against UC has not yet been elucidated.Herein,we aimed to investigate the modulatory effect of SP on microbiota disorders in UC mice and clarify the underlying mechanisms by which SP alleviates damage to the intestinal mucosal barrier.Dextran sulfate sodium(DSS)was used to establish a normal human colonic epithelial cell(NCM460)injury model and UC animal model.The mitochondrial membrane potential assay 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)and staining with Annexin V-fluorescein isothiocyanate(FITC)/propidium iodide(PI)and Hoechst 33258 were carried out to determine the effects of SP on the NCM460 cell injury model.Moreover,hematoxylin and eosin(H&E)staining,transmission electron microscopy(TEM),enzyme-linked immunosorbent assay(ELISA),quantitative real-time polymerase chain reaction(qPCR),western blot,and 16S ribosomal DNA(rDNA)sequencing were used to explore the effects and underlying mechanisms of action of SP on UC in C57BL/6 mice.In vitro studies showed that SP alleviated DSS-induced NCM460 cell injury.SP also significantly reduced the excessive generation of intracellular reactive oxygen species(ROS)and prevented mitochondrial membrane potential reduction after DSS challenge.In vivo studies indicated that SP administration could alleviate the severity of DSS-induced colonic mucosal damage compared with the control group.Inhibition of inflammation and oxidative stress was associated with increases in the activity of antioxidant enzymes and the expression of tight junction proteins(TJs)post-SP treatment.SP improved gut microbiota disorder mainly by increasing antioxidant enzyme activity and the expression of TJs in the colon.Our findings demonstrate that the protective effect of SP against UC is based on its inhibition of pro-inflammatory cytokine overproduction,inhibition of DSS-induced ROS production,and enhanced expression of antioxidant enzymes and TJs in the colonic mucosal barrier. | Jian WANG Liqian SU Lun ZHANG Jiali ZENG Qingru CHEN Rui DENG Ziyan WANG Weidong KUANG Xiaobao JIN Shuiqing GUI Yinghua XU Xuemei LU | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，6： | 3 |
| 10 | Validation of significant wave height retrieval from co-polarization Chinese Gaofen-3 SAR imagery using an improved algorithm显示文摘Chinese Gaofen-3(GF-3) is the first civilian satellite to carry C-band(5.3 GHz) synthetic aperture radar(SAR).During the period of August 2016 to December 2017, 1 523 GF-3 SAR images acquired in quad-polarization(vertical-vertical(VV), horizontal-horizontal(HH), vertical-horizontal(VH), and horizontal-vertical(HV)) mode were recorded, mostly around China's seas. In our previous study, the root mean square error(RMSE) of significant wave height(SWH) was found to be around 0.58 m when compared with retrieval results from a few GF-3 SAR images in co-polarization(VV and HH) with moored measurements by using an empirical algorithm CSAR_WAVE. We collected a number of sub-scenes from these 1 523 images in the co-polarization channel,which were collocated with wind and SWH data from the European Centre for Medium-Range Weather Forecasts(ECMWF) reanalysis field at a 0.125° grid. Through the collected dataset, an improved empirical wave retrieval algorithm for GF-3 SAR in co-polarization was tuned, herein denoted as CSAR_WAVE2. An additional 92 GF-3 SAR images were implemented in order to validate CSAR_WAVE2 against SWH from altimeter Jason-2, showing an about 0.52 m RMSE of SWH for co-polarization GF-3 SAR. Therefore, we conclude that the proposed empirical algorithm has a good performance for wave retrieval from GF-3 SAR images in co-polarization. | SHENG Yexin SHAO Weizeng ZHU Shuai SUN Jian YUAN Xinzhe LI Shuiqing SHI Jian ZUO Juncheng | 2018 | Acta Oceanologica Sinica2018，37，6： | 3 |
| 11 | Performance Study Based on Inner Flow Field Numerical Simulation of Magnetic Drive Pumps with Different Rotate Speeds显示文摘Magnetic drive pump has gotten great achievement and has been widely used in some special fields.Currently,the researches on magnetic drive pump have focused on hydraulic design,bearing,axial force in China,and a new magnetic drive pump with low flow and high head have been developed overseas.However,low efficiency and large size are the common disadvantages for the magnetic drive pump.In order to study the performance of high-speed magnetic drive pump,FLUENT was used to simulate the inner flow field of magnetic drive pumps with different rotate speeds,and get velocity and pressure distributions of inner flow field.According to analysis the changes of velocity and pressure to ensure the stable operation of pump and avoid cavitation.Based on the analysis of velocity and pressure,this paper presents the pump efficiency of magnetic drive pumps with different rotated speeds by calculating the power loss in impeller and volute,hydraulic loss,volumetric loss,mechanical loss and discussing the different reasons of power loss between the magnetic drive pumps with different rotated speeds.In addition,the magnetic drive pumps were tested in a closed testing system.Pressure sensors were set in inlet and outlet of magnetic drive pumps to get the pressure and the head,while the pump efficiency could be got by calculating the power loss between the input power and the outlet power.The results of simulation and test were similar,which shows that the method of simulation is feasible.The proposed research provides the instruction to design high-speed magnetic drive pump. | KONG Fanyu SHEN Xiaokai WANG Wenting ZHOU Shuiqing | 2012 | Chinese Journal of Mechanical Engineering2012，25，1： | 2 |
| 12 | Long-term trends of precipitation and erosivity over Northeast China during 1961-2020显示文摘Northeast China(NEC)is one of the vital commercial grain bases in China and it has suffered from soil erosion due to prolonged cultivation and lack of protection.To determine long-term trends of precipi-tation and rainfall erosivity over NEC during the latest decades,daily precipitation for the entire year during 1961-2020 and hourly precipitation for the warm season(May to September)during 1971-2020 were collected for 192 and 126 stations,respectively.Three seasons,including the cold season(October to April),early warm season(May to June),and late warm season(July to September)were divided according to the combination of precipitation and vegetation.Results demonstrate:(1)Daily precipita-tion reveals total precipitation and rainfall erosivity in the cold season and early warm season increase significantly at relative rates of 3.1%-6.1%compared with the average during 1961-2020,and those in the late warm season decrease insignificantly.(2)Hourly precipitation reveals storms occurring in the early and late warm seasons have undergone significant increasing changes,which shift towards longer storm duration,larger amount,peak intensity,kinetic energy,and rainfall erosivity during 1971-2020.Moreover,the frequency of extreme storms increased.(3)Rainfall erosivities estimated from daily pre-cipitation during 1971-2020 increase insignificantly for the early and late warm season,whereas those from hourly precipitation increase significantly(6.1%and 5.5%,respectively),which indicates daily precipitation may not be able to capture the trend fully under the warming background,and precipi-tation at higher resolutions than the daily scale is necessary to detect trends of rainfall erosivity more accurately. | Wenting Wang Shuiqing Yin Juan Yu Zeng He Yun Xie | 2023 | International Soil and Water Conservation Research2023，11，4： | 2 |
| 13 | SCFP, a novel fiber-specific promoter in cotton显示文摘To investigate the expression pattern of GhSCFP which was isolated from cotton fiber cDNA library, a 1006 bp upstream fragment of the gene was cloned by chromosome walking and fused to GUS and GFP respectively. Histochemical GUS and GFP fluorescence analysis revealed that the expression of the report genes driven by the promoter sequence was detectable only in outer layer cells during the seed development in the transgentic tobaccos. In transgenic cotton, strong GUS activity was observed in spherical protrusions on 0 dpa (days post anthesis) ovule surface, and in the 2―36 dpa fiber cells, while no GUS signals were detected in the root, leaves, stem, corolla, anther and stigma. Our data demonstrated that GhSCFP upstream sequence is a cotton fiber-specific promoter and this promoter will be useful in the molecular research on fiber cell development and in cotton fiber improvements by genetic modification. | HOU Lei LIU Hao LI JiaBao YANG Xia XIAO YueHua LUO Ming SONG ShuiQing YANG GuangWei PEI Yan | 2008 | Chinese Science Bulletin2008，53，17： | 2 |
| 14 | The pyrogenation research of paper making filth in turning kiln显示文摘 | Li Shuiqing(李水清) Li Aimin(李爱民)and Ren Yuan(任远) | 1999 | Journal of Engineering Thermophysics(工程热物理学报)1999，3，： | 1 |
| 15 | Fine particulate formation and ash deposition during pulverized coal combustion of high-sodium lignite in a down-fired furnace显示文摘 | GENGDA L SHUIQING L QIAN H QIANG Y | 2015 | Fuel2015，143，： | 1 |
| 16 | Foxos integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis显示文摘 | Tsuchiya K Tanaka J Shuiqing Y | 2012 | Cell Metab2012，15，3： | 1 |
| 17 | Mobile pay-ment services adoption across time: an empirical study of the effects of behavioral beliefs, social influences, and per- sonal traits 显示文摘 | Yang Shuiqing Lu Yaobin GUPTA S | 2012 | Computers in Human behavior2012，28，1： | 1 |
| 18 | A study on factors that affect users' behavioral intention to transfer usage from the offline to the online chan- nel 显示文摘 | Lu Yaobin Cao Yuzhi Wang Bing Yang Shuiqing | 2011 | Computers in Human Behavior2011，27，1： | 1 |
| 19 | A genome-wide comparison of genes responsive to autopolyploidy inIsatis indigotica usingArabidopsis thaliana Affymetrix genechips显示文摘 | Beibei Lu Xinzhu Pan Lei Zhang Beibei Huang Lianna Sun Bin Li Bo Yi Shuiqing Zheng Xiaojing Yu Ruxian Ding Wansheng Chen | 2006 | Plant Molecular Biology Reporter2006，，2： | 1 |
| 20 | Investigation on the characteristics and mechanisms of unusual heat transt'er of supercritical pressure water in vertically-upward tubes 显示文摘 | Wang Jianguo Li Huixiong Yu Shuiqing Chen Tingkuan | 2011 | International Journal of Heat and Mass Transfer2011，4，910： | 1 |
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