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| 1 | Metachronous gastric cancer after successful Helicobacter pylori eradication显示文摘The high incidence of gastric cancer in Japan initially resulted in establishment of a country-wide gastric cancer screening program to detect early and treatable cancers. In 2013 countrywide Helicobacter pylori(H. pylori) eradication was approved coupled with endoscopy to assess for the presence of chronic gastritis. Current data support the notion that cure of the infection in those with non-atrophic gastritis will prevent development of gastric cancer. However, while progression to more severe damage is halted in those who have already developed, atrophic gastritis/gastric atrophy remain at risk for subsequent development of gastric cancer. That risk is directly related to the extent and severity of atrophic gastritis. Methods to stratify cancer risk include those based on endoscopic assessment of the atrophic border, histologic grading, and non-invasive methods based on serologic testing of pepsinogen levels. Continued surveillance is required because those with atrophic gastritis/gastric atrophy retain considerable gastric cancer risk even after H. pylori eradication. Those who have already experienced a resectable early gastric cancer are among those at highest risk as metachronous lesions are frequent even after H. pylorieradication. We review the role of H. pylori and effect of H. pylori eradication indicating the incidence and the predictive factors on development of metachronous cancer after endoscopic therapy of early gastric cancer. Studies to refine risk markers to stratify for risk, surveillance methods, intervals, and duration after successful H. pylori eradication, and whether adjuvant therapy would change risk are needed. | Akiko Shiotani Ken Haruma David Y Graham | 2014 | World Journal of Gastroenterology2014，20，33： | 5 |
| 2 | Hepatocyte growth factor and transforming growth factor β1 contribute to regeneration of small-for-size liver graft immediately after transplantation显示文摘 | Mizuki Ninomiya Noboru Harada Satoko Shiotani Shoji Hiroshige Ryosuke Minagawa Yuji Soejima Taketoshi Suehiro Takashi Nishizaki Mitsuo Shimada Keizo Sugimachi | 2003 | Transplant International2003，，11： | 2 |
| 3 | H. pylori eradication did not improve dysregulation of specific oncogenic miRNAs in intestinal metaplastic glands显示文摘 | Akiko Shiotani Noriya Uedo Hiroyasu Iishi Takahisa Murao Tomoko Kanzaki Yoshiki Kimura Tomoari Kamada Hiroaki Kusunoki Kazuhiko Inoue Ken Haruma | 2012 | Journal of Gastroenterology2012，，9： | 2 |
| 4 | Therapeutic effects of antibacterial treatment for intractable skin diseases in Helicobacter pylori-positive Japanese patients 显示文摘 | SAKURANE M SHIOTANI A FURUKAWA F | 2002 | J Dermatol2002，29，1： | 1 |
| 5 | New concepts of resistance in the treatment of Helicobacter pylori infections 显示文摘 | GRAHAM D Y SHIOTANI A | 2008 | Nat Clin Pract Gastr2008，5，： | 1 |
| 6 | Involvement of Rho-kinase in cold ischemia-reperfusion injury after liver transplantation in rats显示文摘 | SHIOTANI S SHIMADA M SUEHIRO T | | 0，，03： | 1 |
| 7 | Wild growing forage plants of the Far East, especially Japan, suitable for breeding purposes, part 1, Karyological study in Miscanthus ( 1 ) 显示文摘 | Adati S Shiotani I | 1956 | Bulletin of the Faculty of Agriculture Mie University1956，，12： | 1 |
| 8 | Auxiliary partial orthotopic liver transplantation from living donors显示文摘 | Ikegami T Shiotani S Ninomiya M | 2002 | Surgery2002，131，1： | 1 |
| 9 | Effects of electroacupuncture on gastric myoelectrical activity in healthy humans 显示文摘 | Shiotani A Tatewaki M Hoshino E | 2004 | Neurogastroenterol Motil2004，16，3： | 1 |
| 10 | Active accumulation of gold nanorods in tumor in response to near-infrared laser irradiation显示文摘 | Shiotani A Akiyama Y Kawano T | 2010 | Bioconjug Chem2010，21，11： | 1 |
| 11 | Acoustic emission Shigeishi, Masayasu characteristics of concrete-piles 显示文摘 | Tomoki Shiotani Mitsuhiro Ohtsu | 1999 | Construction and Building Materials1999，13，1： | 1 |
| 12 | Detection and evaluation of AE waves due to rock deformation显示文摘 | Tomoki Shiotani Masayasu Ohtsu | 2001 | Construct Build Mater2001，，15： | 1 |
| 13 | Fertilization and pregnancy using eryopreserved testieular sperm for intracy- toplasmic sperm injection with azoospermia 显示文摘 | Ishikawa T Shiotani M Izumi Y | 2009 | Fertil Steri12009，92，1： | 1 |
| 14 | Characteristic of liver graft in living donor adult liver transplantation:comparison between right-and-left -lobe graft显示文摘 | MISTSUO SHIMADA M D SUTOKO SHIOTANI M D MIZUKI NlNOMIYA M D | 2002 | Arch surg2002，137，： | 1 |
| 15 | Interactions between different genotypic tissues in citrus graft chimeras 显示文摘 | Zhou J M Hirata Y Nou I S Shiotani H Ito T | 2002 | Euphytica2002，126，： | 1 |
| 16 | Increased expression of cyclooxygenase-2 protein in 4-nitroquinoline-1-oxid-induced rat tongue carcinomas and chemopreventive efficacy of a specific inhibitor,nirnesulide显示文摘 | SHIOTANI H DENDA A YAMAMOTO K | 2001 | Cancer Res2001，61，4： | 1 |
| 17 | Adenoviral GDNF gene transfer prevents motoneuron loss in the nucleus ambiguous 显示文摘 | Saito K Shiotani A Watabe K | 2003 | Brain Res2003，962，： | 1 |
| 18 | Characteris- tics of liver grafts in living-donor adult liver transplanta- tion:comparison between right- and left-lobe grafts 显示文摘 | Shimada M Shiotani S Ninomiya M | 2002 | Arch Surg2002，137，： | 1 |
| 19 | IGF-I gene transfer into denervated rat laryngeal muscle显示文摘 | Flint PW Shiotani A O'Malley BW | 1999 | Arch Otolaryngol Head Neck Surg1999，125，： | 1 |
| 20 | Differential effects of enalapril and nitrendipine on the fibrinolytic system in essential hypertension显示文摘 | Sakata K Shiotani M Yoshida H | 1999 | Am Heart J1999，137，： | 1 |
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