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| 1 | 术前肌电图和脑干听觉诱发电位与面肌痉挛微血管减压术后迟发性面瘫发生的关系(英文)显示文摘Background Delayed facial palsy ( DFP) after microvascular decompression ( MVD) in patients with hemifacial spasm ( HFS) is not uncommon,but the cause remains unknown. Objectives To assess whether intraoperative electromyography ( EMG) and brainstem auditory evoked potential ( BAEP) can predict DFP after MVD. Methods Between September 2009 and February 2011 we examined 86 patients,9 of whom ( 10. 4% ) developed DFP after MVD on the same side. All patients underwent MVD and were followed - up for a median period of 13 months ( range 6-22) . We retrospectively examined intraoperative facial EMG and BAEP findings using our MVD patients' registry. We excluded secondary HFS and immediate postoperative facial palsy after MVD in this study. We assessed the prevalence and clinical characteristics of DFP and compared EMG and BAEP findings between DFP and non-DFP groups. Results: All pa- tients recovered completely,with a mean time to recovery of 37. 8 days ( range 22-57) . There were no significant differences between DFP and non - DFP patients in terms of the amplitude and latency of intraoperative EMG and BAEP. Conclusion The usefulness of intraoperative facial EMG and BAEP is limited and cannot predict DFP after MVD for HFS. We speculate that DFP after MVD is not associated with permanent nerve damage according to the EMG findings. | Kim HJ Park YS Ryu JS Huh R Han I Shin DA Kim TG Cho KG Chung SS | 2012 | 中华神经外科疾病研究杂志2012，11，4： | 13 |
| 2 | Influence of the molecular structure of metal-phthalocyanine on electrocatalytic reactions显示文摘The demand for new catalysts for renewable energy production has become crucial.As an alternative to metal catalysts for electrocatalysis to produce energy sources,metal-phthalocyanine(MPc)electrocatalysts have shown potential.Their physicochemical and electrochemical properties depend on the chemical structure of the MPc and the central metal atom.Recent reviews of MPcs focused on their electrochemical performance in specific catalytic reactions,such as oxygen reduction reaction and CO_(2)reduction reaction.However,understanding the structure of MPcs in depth is important,since their electrochemical catalytic activity is affected by structural modifications of MPcs.Therefore,this minireview focuses on how the molecular structure of MPcs affects electrochemical catalysis. | Da Sol Jeong Hyeon Suk Shin Jieun Yang | 2022 | Science China Materials2022，65，12： | 2 |
| 3 | Anti-osteoarthritis effect of a combination treatment with human adipose tissue-derived mesenchymal stem cells and thrombospondin 2 in rabbits显示文摘BACKGROUND Osteoarthritis(OA),a chronic age-related disease characterized by the slowly progressive destruction of articular cartilage,is one of the leading causes of disability.As a new strategy for treatment of OA,mesenchymal stem cells(MSCs)have the potential for articular cartilage regeneration.Meanwhile,thrombospondin 2(TSP2)promotes the chondrogenic differentiation of MSCs.AIM To investigate whether TSP2 induces chondrogenic differentiation of human adipose-derived MSCs(hADMSCs)and potentiates the therapeutic effects of hADMSCs in OA rabbits.METHODS We investigated the chondrogenic potential of TSP2 in hADMSCs by analyzing the expression of chondrogenic markers as well as NOTCH signaling genes in normal and TSP2 small interfering RNA(siRNA)-treated stem cells.Anterior cruciate ligament transection surgery was performed in male New Zealand white rabbits,and 8 wk later,hADMSCs(1.7×10^6 or 1.7×10^7 cells)were injected into the injured knees alone or in combination with intra-articular injection of TSP2(100 ng/knee)at 2-d intervals.OA progression was monitored by gross,radiological,and histological examinations.RESULTS In hADMSC culture,treatment with TSP2 increased the expression of chondrogenic markers(SOX9 and collagen Ⅱ)as well as NOTCH signaling genes(JAGGED1 and NOTCH3),which were inhibited by TSP2 siRNA treatment.In vivo,OA rabbits treated with hADMSCs or TSP2 alone exhibited lower degree of cartilage degeneration,osteophyte formation,and extracellular matrix loss 8 wk after cell transplantation.Notably,such cartilage damage was further alleviated by the combination of hADMSCs and TSP2.In addition,synovial inflammatory cytokines,especially tumor-necrosis factor-α,markedly decreased following the combination treatment.CONCLUSION The results indicate that TSP2 enhances chondrogenic differentiation of hADMSCs via JAGGED1/NOTCH3 signaling,and that combination therapy with hADMSCs and TSP2 exerts synergistic effects in the cartilage regeneration of OA joints. | Kyungha Shin Yeseul Cha Young-Hwan Ban Da Woom Seo Ehn-Kyoung Choi Dongsun Park Sung Keun Kang Jeong Chan Ra Yun-Bae Kim | 2019 | World Journal of Stem Cells2019，11，12： | 2 |
| 4 | Blood pressure, haemorrhagic stroke, and ischaemic stroke: the Korean national prospective occupational cohort study 显示文摘 | Song YM Sung J Lawlor DA Smith DG Shin Y Ebrahim S | 2004 | BM J2004，328，12： | 1 |
| 5 | Tissue engineered regeneration of completely transected spinal cord using human mesenchymal stem cells显示文摘 | Kkot Nim Kang Da Yeon Kim So Mi Yoon Ju Young Lee Bit Na Lee Jin Seon Kwon Hyo Won Seo Il Woo Lee Ha Cheol Shin Young Man Kim Hyun Soo Kim Jae Ho Kim Byoung Hyun Min Hai Bang Lee Moon Suk Kim | 2012 | Biomaterials2012，，19： | 1 |
| 6 | Arterial coupling for mi- crovaseular free tissue transfer in head and neck reconstruc- tion显示文摘 | Ross DA Chow JY Shin J | 2005 | Arch Otolaryngol Head Neck Surg2005，131，10： | 1 |
| 7 | The efficacy of microendoscopic discectomy in reducing iatrogenic muscle injury显示文摘 | Shin DA Kim KN Shin HC | | 0，，01： | 1 |
| 8 | Artificial disc replacement combined with fusion versus two-level fusion disc disease显示文摘 | Shin DA Yi S Yoon do H | 2009 | Spine2009，34，11： | 1 |
| 9 | Usefulness of pain distribution pattern assessment in decision - making for the patients with lumbar zygapophyseal and sacroiliac joint arthropathy 显示文摘 | Jung JH Kim HI Shin DA | 2007 | J Korean Med Sci2007，22，： | 1 |
| 10 | Coregulation of CD8 T cell exhaustion by multiple in- hibitory receptors during chronic viral infection 显示文摘 | Blackburn SD Shin H Haining WN Zou T Workman CJ Polley A Betts MR Freeman GJ Vignali DA Wherry F_J | 2009 | Nat Immunol2009，10，1： | 1 |
| 11 | The efficacy of microendoscopic Discectomy in reducing iatrogenic muscle injury显示文摘 | Shin DA Kim KN Shin HC | | 0，，： | 1 |
| 12 | Artificial disc replacement com- bined with fusion versus two-level fusion in cervical two-level disc disease显示文摘 | Shin DA Yi S Yoondo H | 2009 | Spine2009，34，11： | 1 |
| 13 | Arterial coupling for microvascular free tissue transfer 显示文摘 | Chernichenko N Ross DA Shin J | 2008 | Otolaryngol Head Neck Surg2008，138，： | 1 |
| 14 | The efficacy of microendoscopic discectomy in reducing iatrogenic muscle injury 显示文摘 | Shin DA Kim KN Shin HC | 2008 | J Neurosurg Spine2008，8，1： | 1 |
| 15 | End - to - side venous anastomosis with an anastomotic coupling device for microvascular free - tissue transfer in head and neck recon- struction显示文摘 | Chernichenko N Ross DA Shin J | 2008 | Laryngoscope2008，118，： | 1 |
| 16 | Factors influencing manometric pressure during pressure - controlled discography 显示文摘 | Shin DA Kim SH Han IB | 2009 | Spine ( Phila Pa 1976 )2009，34，： | 1 |
| 17 | Artificial disc replacement combined with fusion versus two-level fusion in cervical two-level disc disease显示文摘 | Shin DA Yi S Yoon do H | 2009 | Spine2009，34，11： | 1 |
| 18 | Impaired therapeutic capacity of autologous stem cells in a model of type 2 diabetes显示文摘 | Shin L Peterson DA | | 0，，02： | 1 |
| 19 | Diagnostic relevance of pressure-controlled discography显示文摘 | Shin DA Kim HI Jung JH | 2006 | J Korean Med Sci2006，21，5： | 1 |
| 20 | The predisposing factors for the heterotopic ossification after cervical artificial disc replacement显示文摘 | Yi S Shin DA Kim KN | 2013 | Spine J2013，13，9： | 1 |
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