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| 1 | Adenomyosis uterine innervation in mice correlates to nerve growth factor expression,inflammation,and vascularization显示文摘BACKGROUND: Studies have shown that abnormal innervation is an important factor impacting occurrence and development of pathological pain in endometriosis. OBJECTIVE: To observe uterine innervation of adenomyosis mice and to analyze the cause of innervation changes due to nerve growth factor (NGF) expression, inflammation, and vascularization. DESIGN, TIME AND SETTING: This randomized, controlled, animal experiment was performed at the Research Institute of Obstetrics and Gynecology Hospital, and Central Laboratory of Zhong- shan Hospital, Fudan University from March to December 2008. MATERIALS: Tamoxifen was provided by Fudan Forward, China. Rabbit anti-mouse NGF was purchased from Santa Cruz Corporation, USA; rabbit anti-protein gene product 9.5 (PGP9.5) and rabbit antisubstance P (SP) were purchased from Chemicon, USA. METHODS: A total of 40 newborn ICR mice were randomly assigned to adenomyosis model and control groups, with 20 animals in each group. Mice in the adenomyosis model group were orally administrated 2.7 μmol/kg tamoxifen on days 2-5 after birth, while the controls were not treated. MAIN OUTCOME MEASURES: Both uteri from all mice were harvested at days 135-145 after birth. Expressions of polyclonal PGP9.5 and SP were immunohistochemically detected to demonstrate pan- and sensory nerve fibers. Microvessel density was quantified in the endometrium and myometrium using immunochemical staining for polyclonal rabbit anti-CD31, which stained vessels. Gene expression for NGF, high-affinity tyrosine kinase receptor (trkA), p75 neurotrophin receptor (p75NTR), bradykinin receptor-1 (BKR-1), and 2 (BKR-2), as well as substance P receptor (neurokinin1 receptor, NK1-R), were detected by reverse transcription-polymerase chain reaction. NGF-β protein expression was detected by Western blot analysis. RESULTS: More nerve fibers were stained with PGP9.5 in the endometrium and myometrium, and with SP in the endometrium, in adenomyosis mice compared with controls (P < 0.01 and P < 0.05). Microvessel density in the myometrium of adenomyosis mice was significantly greater than the controls (P < 0.01). In the uterus of adenomyosis mice, mRNA expression of NGF and its two receptors (trkA and p75 NTR), BKR-1, and NK1-R, as well as protein expression of NGF-β, were greater than the control mice (P < 0.01 or P < 0.05). CONCLUSION: Uterine innervation in the adenomyosis mice was increased compared with the controls. Moreover, NGF expression, inflammation, and vascularization, which have been shown to be impact factors of innervation, were abnormal in the uteri of adenomyosis mice. | Yan Li Shaofen Zhang Xian Xia Shien Zou | 2010 | Neural Regeneration Research2010，5，1： | 9 |
| 2 | PERFORMANCE IMPROVEMENT OF CENTRIFUGAL FAN BY MEANS OF NUMERICAL SIMULATION显示文摘数字模拟被用来在一台模型离心通风机调查流动地让蒸气发电站以便改进表演。在测试模型扇子期间,效率仅仅与入口盒子是 62.5% ,这被发现,没有它效率是 83% 。另外,测试钻塔的强壮的颤动与入口盒子被观察。如果扇子的气体动力学能被学习,它将是高度合乎需要的。因此,数字模拟被执行与入口盒子调查一把模型扇子的内部流动特征。从入口的整个区域关的 CFD 分析表演的结果被作为转子的方向相反地旋转的一个螺线旋涡占据,它显著地在扇子内影响大多数流动区域。为这个原因,一个哑巴盘子在入口盒子中被安排阻碍螺线旋涡的产生,从在改革以后的 CFD 的结果证明修正是安静的有效,以前的大螺线顶点有效地被破坏了,大的被代替赞成二个小旋涡。然而,二个小旋涡在转子和下列部分的内部流动上有小效果。最后,模型扇子的效率被测试改进,测试钻塔的强壮的颤动消失。这类修正尽最大努力被使用了车站,扇子效率成功地涨到 84% 。 | ZHANG Bo HUANG Shujuan SUN Zhongwei HUI Shien LIU Jiayu QI Chunsong | 2006 | Chinese Journal of Mechanical Engineering2006，19，1： | 8 |
| 3 | Digital assembly technology based on augmented reality and digital twins: a review显示文摘Product assembly simulation is considered as one of the key technologies in the process of complex product design and manufacturing.Virtual assembly realizes the assembly process design,verification,and optimization of complex products in the virtual environment,which plays an active and effective role in improving the assembly quality and efficiency of complex products.In recent years,augmented reality(AR)and digital twin(DT)technology have brought new opportunities and challenges to the digital assembly of complex products owing to their characteristics of virtual reality fusion and interactive control.This paper expounds the concept and connotation of AR,enumerates a typical AR assembly system structure,analyzes the key technologies and applications of AR in digital assembly,and notes that DT technology is the future development trend of intelligent assembly research. | Chan QIU Shien ZHOU Zhenyu LIU Qi GAO Jianrong TAN | 2019 | Virtual Reality & Intelligent Hardware2019，1，6： | 7 |
| 4 | Impacts of Large-scale Wind Power Grid Integration on Relay Protection and Countermeasures显示文摘Several large-scale wind turbine tripping accidents occurred in Jiuquan wind power base in 2011.According to the on-site survey and analysis of these accidents related to relay protection,causes were found to be the collection system defects and low correct operation rate of small current grounded line selectors of the unearthed neutral point collection system.By referring to both the characteristics of Jiuquan wind power base and arrangement of relay protection,the short-circuit features of wind power and its impacts on relay protection are analyzed.The collection system and the retrofit of the small current grounded line selector are improved by specific countermeasures.Finally,further research subjects are put forward. | He, Shien Suonan, Jiale Kang, Xiaoning Song, Guobing | 2012 | 电力系统自动化2012，36，8： | 6 |
| 5 | The relations among the three kinds of conditional risk measures显示文摘Let(Ω,E,P)be a probability space,F a sub-σ-algebra of E,Lp(E)(1 p+∞)the classical function space and Lp F(E)the L0(F)-module generated by Lp(E),which can be made into a random normed module in a natural way.Up to the present time,there are three kinds of conditional risk measures,whose model spaces are L∞(E),Lp(E)(1 p<+∞)and Lp F(E)(1 p+∞)respectively,and a conditional convex dual representation theorem has been established for each kind.The purpose of this paper is to study the relations among the three kinds of conditional risk measures together with their representation theorems.We first establish the relation between Lp(E)and Lp F(E),namely Lp F(E)=Hcc(Lp(E)),which shows that Lp F(E)is exactly the countable concatenation hull of Lp(E).Based on the precise relation,we then prove that every L0(F)-convex Lp(E)-conditional risk measure(1 p+∞)can be uniquely extended to an L0(F)-convex Lp F(E)-conditional risk measure and that the dual representation theorem of the former can also be regarded as a special case of that of the latter,which shows that the study of Lp-conditional risk measures can be incorporated into that of Lp F(E)-conditional risk measures.In particular,in the process we find that combining the countable concatenation hull of a set and the local property of conditional risk measures is a very useful analytic skill that may considerably simplify and improve the study of L0-convex conditional risk measures. | GUO TieXin ZHAO ShiEn ZENG XiaoLin | 2014 | Science China Mathematics2014，57，8： | 6 |
| 6 | Cytogenetic and molecular aberrations of multiple myeloma patients: a single-center study in Singapore显示文摘 | LIM Alvin Soon Tiong LIM Tse Hui SEE Karen Hsu Shien NG Yit Jun TAN Yu Min CHO0 Natasha Swee Lian LIM Sherry Xin Er YEE Yenny LAU Lai Ching TIEN Sim Leng Kumar Sathish TAN Daryl Chen Lung | 2013 | Chinese Medical Journal2013，，10： | 4 |
| 7 | N-doped carbon supported Pd catalysts for N-formylation of amines with CO2/H2显示文摘Using mesoporous N-doped carbons(NCs)derived from glucose and melamine as the supports,a series of Pd/NC catalysts were prepared,in which Pd nanoparticles with average size<2.0 nm were uniformly distributed on the supports.It was indicated that the resultant Pd/NC catalysts were effective for N-formylation of amines with CO_2and H_2in ethanol without any additives.Especially,the catalyst Pd/NC-800-6.9%containing quaternary N showed the best performance,affording a series of formylamides in good or even excellent yields.Further investigation reveals that the interaction between the Pd nanoparticles and quaternary nitrogen in the NC support was responsible for the good performance of the catalyst. | Xiaoying Luo Hongye Zhang Zhengang Ke Cailing Wu Shien Guo Yunyan Wu Bo Yu Zhimin Liu | 2018 | Science China Chemistry2018，61，6： | 4 |
| 8 | Catalytic steam reforming of tar for enhancing hydrogen production from biomass gasification:a review显示文摘Presently,the global search for alternative renewable energy sources is rising due to the depletion of fossil fuel and rising greenhouse gas(GHG)emissions.Among alternatives,hydrogen(H2)produced from biomass gasification is considered a green energy sector,due to its environmentally friendly,sustainable,and renewable characteristics.However,tar formation along with syngas is a severe impediment to biomass conversion efficiency,which results in process-related problems.Typically,tar consists of various hydrocarbons(HCs),which are also sources for syngas.Hence,catalytic steam reforming is an effective technique to address tar formation and improve H2 production from biomass gasification.Of the various classes in existence,supported metal catalysts are considered the most promising.This paper focuses on the current researching status,prospects,and challenges of steam reforming of gasified biomass tar.Besides,it includes recent developments in tar compositional analysis,supported metal catalysts,along with the reactions and process conditions for catalytic steam reforming.Moreover,it discusses alternatives such as dry and autothermal reforming of tar. | Ru Shien TAN Tuan Amran TUAN ABDULLAH Anwar JOHARI Khairuddin MD ISA | 2020 | Frontiers in Energy2020，14，3： | 4 |
| 9 | Brain areas activated by uncertain reward-based decision-making in healthy volunteers显示文摘Reward-based decision-making has been found to activate several brain areas,including the ventrolateral prefrontal lobe,orbitofrontal cortex,anterior cingulate cortex,ventral striatum,and mesolimbic dopaminergic system.In this study,we observed brain areas activated under three degrees of uncertainty in a reward-based decision-making task(certain,risky,and ambiguous).The tasks were presented using a brain function audiovisual stimulation system.We conducted brain scans of15 healthy volunteers using a 3.0T magnetic resonance scanner.We used SPM8 to analyze the location and intensity of activation during the reward-based decision-making task,with respect to the three conditions.We found that the orbitofrontal cortex was activated in the certain reward condition,while the prefrontal cortex,precentral gyrus,occipital visual cortex,inferior parietal lobe,cerebellar posterior lobe,middle temporal gyrus,inferior temporal gyrus,limbic lobe,and midbrain were activated during the‘risk’condition.The prefrontal cortex,temporal pole,inferior temporal gyrus,occipital visual cortex,and cerebellar posterior lobe were activated during ambiguous decision-making.The ventrolateral prefrontal lobe,frontal pole of the prefrontal lobe,orbitofrontal cortex,precentral gyrus,inferior temporal gyrus,fusiform gyrus,supramarginal gyrus,inferior parietal lobule,and cerebellar posterior lobe exhibited greater activation in the‘risk’than in the‘certain’condition(P<0.05).The frontal pole and dorsolateral region of the prefrontal lobe,as well as the cerebellar posterior lobe,showed significantly greater activation in the‘ambiguous’condition compared to the‘risk’condition(P<0.05).The prefrontal lobe,occipital lobe,parietal lobe,temporal lobe,limbic lobe,midbrain,and posterior lobe of the cerebellum were activated during decision-making about uncertain rewards.Thus,we observed different levels and regions of activation for different types of reward processing during decision-making.Specifically,when the degree of reward uncertainty increased,the number of activated brain areas increased,including greater activation of brain areas associated with loss. | Zongjun Guo Juan Chen Shien Liu Yuhuan Li Bo Sun Zhenbo Gao | 2013 | Neural Regeneration Research2013，8，35： | 3 |
| 10 | Comparative pathological studies on domestic geese (Anser anser domestica)and Muscovy ducks (Cairina moschata)experimentally infected with parvovirus strains of goose and Muscovy duck origin显示文摘 | Wang C Y Shieh H K Shien J H | 2005 | Acta Vet Hung2005，53，1： | 1 |
| 11 | The gap -junctional protein connexin40 is elevated in patients susceptible to postoperative atrial fibrillation显示文摘 | Dupont E Yu Shien K Stephen R | 2001 | Circulation2001，103，6： | 1 |
| 12 | Identification and subtyping of avian influenza viruses by reverse tran-scription-PCR 显示文摘 | Lee M S Chang P C Shien J H | 2001 | J Virol Methods2001，97，12： | 1 |
| 13 | RFID Implementation and Benefits' in Libraries 显示文摘 | Shien - Chiang Y | 2007 | The Electronic Library2007，，1： | 1 |
| 14 | Proceedings of the international conference on fiber reinforced concrete显示文摘 | SHIEN LI GUIHUI WEI LINING YAO | 1997 | Guangzhou:Guangdong Science and Technology Press1997，2733，： | 1 |
| 15 | Acquired resist- ance to EGFR inhibitors is associated with a manifestation of stem cell - like properties in cancer cells 显示文摘 | Shien K Toyooka S Yamamoto H | 2013 | Cancer Res2013，73，10： | 1 |
| 16 | Comparison of the diagnostic values of circulating steroid hormones, VEGF - A, PIGF, and ADAM12 in women with ectopic pregnancy显示文摘 | Shien Zou Xin Li Yi Feng | 2013 | Journal of Trans- lational Medicine2013，11，： | 1 |
| 17 | Synthesis and seectroscopic properties of finite Ph2N-containing oligo (arylenevinulene) derivatives that emit blue to red fluoreseenee显示文摘 | Li Chien Le Shieh S J Lin Shien Chang | 2003 | Org Lett2003，5，7： | 1 |
| 18 | PLC and PI3K pathways are important in the inhibition of EGF-induced cell migration by gefitinib (' Iressa', ZD1839)显示文摘 | SHIEN T DOIHARA H HARA H | 2004 | Breast Cancer2004，11，4： | 1 |
| 19 | The gap junctional protein connexin 40 is elevated in patients susceptible to postoperative atrial fibrillation显示文摘 | Dupont E Yu Shien K Stephen R | 2001 | Circulation2001，103，6： | 1 |
| 20 | Avian reovirus sigma C enhances the mucosal and systemic immune responses elicited by antigen-conjugated lactic acid bacteria显示文摘 | Lin K H Hsu A P Shien J H | 2012 | Vaccine2012，30，33： | 1 |
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