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| 1 | Large-scale analysis of small RNAs derived from traditional Chinese herbs in human tissues显示文摘Plant-derived microRNAs have recently been reported to function in human blood and tissues. Controversy was immediately raised due to possible contamination and the lack of large sample sizes. Here, we report thousands of unique small RNAs derived from traditional Chinese medicine(TCM) herbs found in human blood cells and mouse lung tissues using a large-scale analysis.We extracted small RNAs from decoctions of 10 TCM plants(Ban Zhi Lian, Chai Hu, Chuan Xin Lian, Di Ding Zi Jin, Huang Qin, Jin Yin Hua, Lian Qiao, Pu Gong Ying, Xia Ku Cao, and Yu Xing Cao) and obtained millions of RNA sequences from each herb. We also obtained RNA-Seq data from the blood cells of humans who consumed herbal decoctions and from the lung tissues of mice administered RNAs from herbal decoctions via oral gavage. We identified thousands of unique small RNA sequences in human blood cells and mouse lung tissues. Some of these identified small RNAs from Chuan Xin Lian and Hong Jing Tian could be mapped to the genomes of the herbs, confirming their TCM plant origin. Small RNAs derived from herbs regulate mammalian gene expression in a sequence-specific manner, and thus are a superior novel class of herbal drug components that hold great potential as oral gene-targeted therapeutics, highlighting the important role of herbgenomics in their development. | Fengming Huang Jianchao Du Zhu Liang Zhichao Xu Jiantao Xu Yan Zhao Yexuan Lin Song Mei Quan He Jindong Zhu Qiang Liu Yanxu Zhang Yuhao Qin Wei Sun Jingyuan Song Shilin Chen Chengyu Jiang | 2019 | Science China(Life Sciences)2019，62，3： | 14 |
| 2 | Reconfigurable intelligent surfaces for smart wireless environments:channel estimation,system design and applications in 6G networks显示文摘Reconfigurable intelligent surface(RIS),one of the key enablers for the sixth-generation(6G)mobile communication networks,is considered by designers to smartly reconfigure the wireless propagation environment in a controllable and programmable manner.Specifically,an RIS consists of a large number of low-cost and passive reflective elements(REs)without radio frequency chains.The system gain of RIS wireless systems can be achieved by adjusting the phase shifts and amplitudes of the REs so that the desired signals can be added constructively at the receiver.However,an RIS typically has limited signal processing capability and cannot perform active transmitting/receiving in general,which leads to new challenges in the physical layer design of RIS wireless systems.In this paper,we provide an overview of the RIS-aided wireless systems,including the reflection principle,channel estimation,and system design.In particular,two types of emerging RIS systems are considered:RIS-aided wireless communications(RAWC)and RISbased information transmission(RBIT),where the RIS plays the role of the reflector and the transmitter,respectively.We also envision the potential applications of RIS in 6G networks. | Ying-Chang LIANG Jie CHEN Ruizhe LONG Zhen-Qing HE Xianqi LIN Chenlu HUANG Shilin LIU Xuemin(Sherman)SHEN Marco DI RENZO | 2021 | Science China(Information Sciences)2021，64，10： | 12 |
| 3 | Optimal integration of mobile battery energy storage in distribution system with renewables显示文摘An optimal sizing method is proposed in this paper for mobile battery energy storage system(MBESS)in the distribution system with renewables.The optimization is formulated as a bi-objective problem,considering the reliability improvement and energy transaction saving,simultaneously.To evaluate the reliability of distribution system with MBESS and intermittent generation sources,a new framework is proposed,which is based on zone partition and identification of circuit minimal tie sets.Both analytic and simulation methods for reliability assessment are presented and compared in the framework.Case studies on a modified IEEE benchmark system have verified the performance of the proposed approach. | Yu ZHENG Zhaoyang DONG Shilin HUANG Ke MENG Fengji LUO Jie HUANG David HILL | 2015 | Journal of Modern Power Systems and Clean Energy2015，3，4： | 10 |
| 4 | Allele-aware chromosome-level genome assembly of Artemisia annua reveals the correlation between ADS expansion and artemisinin yield显示文摘Artemisia annua is the major natural source of artemisinin,an anti-malarial medicine commonly used worldwide.Here,we present chromosome-level haploid maps for two A.annua strains with different artemisinin contents to explore the relationships between genomic organization and artemisinin production.High-fidelity sequencing,optical mapping,and chromatin conformation capture sequencing were used to assemble the heterogeneous and repetitive genome and resolve the haplotypes of A.annua.Approximately 5o,ooo genes were annotated for each haplotype genome,and a triplication event that occurred approximately 58.12million years ago was examined for the first time in this species.A total of 3,903,467-5,193,414 variants(SNPs,indels,and structural variants)were identified in the 1.5-Gb genome during pairwise comparison between haplotypes,consistent with the high heterozygosity of this species.Genomic analyses revealed a correlation between artemisinin concents and the copy number of amorpha-4,11-dienes ynthasegenes.This correlation was further confirmed by resequencing of 36A.annua samples with varied artemisinin contents.Circular consensus sequencing of transcripts facilitated the detection of paralog expression.Collectively,our study provides chromosome-level allele-aware genome assemblies for two A.annua strains and new insights into the biosynthesis of artemisinin and its regulation,which will contribute to conquering malaria worldwide. | Baosheng Liao Xiaofeng Shen Li Xiang Shuai Guo Shiyu Chen Ying Meng Yu Liang Dandan Ding Junqi Bai Dong Zhang Tomasz Czechowski Yi Li Hui Yao Tingyu Mai Caroline Howard Chao Sun Haitao Liu Jiushi Liu Jin Pei Jihai Gao Jigang Wang Xiaohui Qiu Zhihai Huang Hongyi Li Ling Yuan Jianhe Wei lan Graham Jiang Xu Boli Zhang Shilin Chen | 2022 | Molecular Plant2022，15，8： | 9 |
| 5 | Temperature-gradient induced microstructure evolution in heat-affected zone of electron beam welded Ti-6Al-4V titanium alloy显示文摘The heat-affected zone(HAZ) of electron beam welded(EBW) joint normally undergoes a unique heat-treating process consisting of rapid temperature rising and dropping stages, resulting in temperature-gradient in HAZ as a function of the distance to fusion zone(FZ). In the current work,microstructure, elements distribution and crystallographic orientation of three parts(near base material(BM) zone, mid-HAZ and near-FZ) in the HAZ of Ti-6Al-4V alloy were systematically investigated. The microstructure observation revealed that the microstructural variation from near-BM to near-FZ included the reduction of primary α(αp) grains, the increase of transformed β structure(βt) and the formation of various α structures. The rim-α, dendritic α and abnormal secondary α(αs) colonies formed in the mid-HAZ, while the 'ghost' structures grew in the near-FZ respectively. The electron probe microanalyzer(EPMA) and electron back-scattered diffraction(EBSD) technologies were employed to evaluate the elements diffusion and texture evolution during the unique thermal process of welding. The formation of the various α structures in the HAZ were discussed based on the EPMA and EBSD results. Finally, the nanoindentation hardness of 'ghost' structures was presented and compared with nearby βt regions. | Shilin Zhang Yingjie Ma Sensen Huang Sabry S.Youssef Min Qi Hao Wang Jianke Qiu Jiafeng Lei Rui Yang | 2019 | Journal of Materials Science & Technology2019，35，8： | 6 |
| 6 | NMRCloudQ: a quantum cloud experience on a nuclear magnetic resonance quantum computer显示文摘Cloud-based quantum computing is anticipated to be the most useful and reachable form for public users to experience with the power of quantum. As initial attempts, IBM Q has launched influential cloud services on a superconducting quantum processor in 2016, but no other platforms has followed up yet. Here,we report our new cloud quantum computing service – NMRCloud Q(http://gffzz93b8cbf03a7349b1hx6cfwkcpfcwk6kxv.ffgz.tsg.suse.edu.cn/zh-hans/),where nuclear magnetic resonance, one of the pioneer platforms with mature techniques in experimental quantum computing, plays as the role of implementing computing tasks. Our service provides a comprehensive software environment preconfigured with a list of quantum information processing packages,and aims to be freely accessible to either amateurs that look forward to keeping pace with this quantum era or professionals that are interested in carrying out real quantum computing experiments in person. In our current version, four qubits are already usable with in average 99.10% single-qubit gate fidelity and 97.15% two-qubit fidelity via randomized benchmaking tests. Improved control precisions as well as a new seven-qubit processor are also in preparation and will be available later. | Tao Xin Shilin Huang Sirui Lu Keren Li Zhihuang Luo Zhangqi Yin Jun Li Dawei Lu Guilu Long Bei Zeng | 2018 | Science Bulletin2018，63，1： | 5 |
| 7 | Compact ultrabroadband light-emitting diodes based on lanthanide-doped lead-free double perovskites显示文摘Impurity doping is an effective approach to tuning the optoelectronic performance of host materials by imparting extrinsic electronic channels.Herein,a family of lanthanide(Ln^(3+))ions was successfully incorporated into a Bi:Cs_(2)AgInCl_(6) lead-free double-perovskite(DP)semiconductor,expanding the spectral range from visible(Vis)to near-infrared(NIR)and improving the photoluminescence quantum yield(PLQY).After multidoping with Nd,Yb,Er and Tm,Bi/Ln:Cs_(2)AgInCl_(6) yielded an ultrabroadband continuous emission spectrum with a full width at half-maximum of~365 nm originating from intrinsic self-trapped exciton recombination and abundant 4f-4f transitions of the Ln^(3+)dopants.Steady-state and transient-state spectra were used to ascertain the energy transfer and emissive processes.To avoid adverse energy interactions between the various Ln^(3+)ions in a single DP host,a heterogeneous architecture was designed to spatially confine different Ln^(3+)dopants via a“DP-in-glass composite”(DiG)structure.This bottom-up strategy endowed the prepared Ln^(3+)-doped DIG with a high PLQY of 40%(nearly three times as high as that of the multidoped DP)and superior long-term stability.Finally,a compact Vis-NIR ultrabroadband(400~2000 nm)light source was easily fabricated by coupling the DiG with a commercial UV LED chip,and this light source has promising applications in nondestructive spectroscopic analyses and multifunctional lighting. | Shilin Jin Renfu Li Hai Huang Naizhong Jiang Jidong Lin Shaoxiong Wang Yuanhui Zheng Xueyuan Chen Daqin Chen | 2022 | Light(Science & Applications)2022，11，3： | 3 |
| 8 | Prompt Electrodeposition of Ni Nanodots on Ni Foam to Construct a High-Performance Water-Splitting Electrode:Efficient, Scalable,and Recyclable显示文摘In past decades,Ni-based catalytic materials and electrodes have been intensively explored as low-cost hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)catalysts for water splitting.With increasing demands for Ni worldwide,simplifying the fabrication process,increasing Ni recycling,and reducing waste are tangible sustainability goals.Here,binder-free,heteroatom-free,and recyclable Ni-based bifunctional catalytic electrodes were fabricated via a one-step quick electrodeposition method.Typically,active Ni nanodot(NiND)clusters are electrodeposited on Ni foam(NF)in Ni(NO3)2 acetonitrile solution.After drying in air,NiO/NiND composites are obtained,leading to a binder-free and heteroatom-free NiO/NiNDs@NF catalytic electrode.The electrode shows high efficiency and long-term stability for catalyzing hydrogen and oxygen evolution reactions at low overpotentials(10ηHER= 119 mV and 50ηOER=360 mV)and can promote water catalysis at 1.70 V@ 10mA cm-2.More importantly,the recovery of raw materials(NF and Ni(NO3)2)is quite easy because of the solubility of NiO/NiNDs composites in acid solution for recycling the electrodes.Additionally,a large-sized(S^70 cm2)NiO/NiNDs@NF catalytic electrode with high durability has also been constructed.This method provides a simple and fast technology to construct high-performance,low-cost,and environmentally friendly Ni-based bifunctional electrocatalytic electrodes for water splitting. | Hongtao Yu Ting Quan Shilin Mei Zdravko Kochovski Wei Huang Hong Meng Yan Lu | 2019 | Nano-Micro Letters2019，11，3： | 2 |
| 9 | Experimental investigation and prediction model for UCS loss of unsaturated sandstones under freeze-thaw action显示文摘Sandstone is widely distributed in cold regions and the freeze-thaw deterioration of them has caused many geological engineering disasters.As an important and direct index of frost resistance,the strength loss of sandstones under freeze-thaw actions should be investigated to provide a guidance for the stability assessment of geological engineering.In this research,the UCS(Uniaxial compressive strength)loss of six typical sandstones with different water contents after 0,20,40 and 60 freeze-thaw cycles was measured in the laboratory.The experimental results indicated that the freeze-thaw damage was more serious in sandstones containing high water contents,and the critical saturations for causing a significant loss of UCS under freeze-thaw were 60%-80%for these sandstones.Below this critical saturation,the UCS loss of the sandstones was mainly caused by water weakening rather than freeze-thaw damage.Besides,a developed strength prediction model was proposed by combining the exponential decay function and multiple linear regression method.The initial porosity,elastic modulus and tensile strength of fresh sandstones were a good parameter combination to accurately determine the decay constant in this developed model.The main novelty of this model is that it can accurately and easily estimate the UCS loss of sandstones after any freeze-thaw cycle only using the initial parameters of fresh sandstones,but it does not need to perform freeze-thaw and mechanical strength experiments.This study not only provides an accurate prediction model of UCS under freeze-thaw,but also makes a contribution to better understanding the frost resistance mechanism of sandstones. | Shibing Huang Yingbo He Shilin Yu Chen Cai | 2022 | International Journal of Mining Science and Technology2022，32，1： | 2 |
| 10 | Effect of Thermal Treatment on the Properties of TEMPO Oxidized Cellulose Film for the Flexible Substrate of Solar Cell显示文摘The 2,2,6,6-tetramethylpiperidine-1-oxyl(TEMPO)oxidized cellulose film(TOCF)has been attempted to be used as a substrate in electronic and optoelectronic devices,but the changes in the TOCF properties before and after annealing treatment have usually been neglected during device fabrication.In this study,TOCF was treated in different atmospheres(air,vacuum,and N2)and at different temperatures,and the properties were investigated.The results indicate that the optical properties are slightly affected by atmosphere and temperature;only slight transmittance loss and haze increase have been observed when TOCF is exposed to an air atmosphere at temperatures of above 120℃.In contrast to the slight effects on the optical properties,cellulose degradation and a loss of film strength have been observed regardless of the atmosphere used when placed at temperatures of above 100℃.Specifically,TOCF was exposed to air,followed by N2 and vacuum atmospheres.Additional Fourier transform infrared(FT-IR)and nuclear magnetic resonance(NMR)results showed that increasing the temperature had no significant effect on the structure of TOCF.Therefore,the annealing temperature should be controlled at a temperature of lower than 100℃and a vacuum atmosphere is preferred. | Changmei Lin Hui Zhang Qidu Deng Liulian Huang Xiaojuan Ma Shilin Cao | 2020 | Paper And Biomaterials2020，5，3： | 2 |
| 11 | Quantum Groups and Double Quiver Algebras显示文摘 | Hua-Lin Huang Shilin Yang | 2005 | Letters in Mathematical Physics2005，，1： | 1 |
| 12 | Effect of surface modification of electrodes on charge injection and dielectric characteristics of propylene carbonate显示文摘Space charge injected into a liquid dielectric by an electrode under an impulse voltage causes the electric field to be distorted,which affects the dielectric's insulation performance.In this study,the authors study the surface modification of three-electrode materials,namely aluminium,copper,and stainless steel,by sputtering of titanium dioxide(TiO2)based on magnetron sputtering.The breakdown voltage of propylene carbonate and the surface morphology of the electrodes before and after modification were examined.Furthermore,the distribution of the space charge injected into the propylene carbonate from the different electrode materials was also measured based on the Kerr electro-optic effect.These results indicate that the breakdown voltage of propylene carbonate increased by 7,4,and 9%after surface modification of aluminium,copper,and stainless steel,respectively.After sputtering of TiO2,micro-grooves on the surface of the three-electrode materials became smooth,and the surface roughness decreased,which changed the barrier height of the solid–liquid interface.The space charge injection mode of the three-electrode materials before and after surface modification was bipolar injection;however,the space charge injection amounts were markedly lower for the modified electrodes. | Shilin Wu Qing Yang Tao Shao Zhaotian Zhang Lingyu Huang | 2020 | High Voltage2020，5，1： | 1 |
| 13 | 50th anniversary of artemisinin:From the discovery to allele-aware genome assembly of Artemisia annua显示文摘Over the past half century,the fight against malaria has been a resounding success mainlydue to thediscoveryof artemisinin.According to the World Health Organization(WHO),morbidity and mortality due to malaria have been cut by half since the promotion of artemisinin-based combination therapy(WHO,2020). | Jiang Xu Baosheng Liao Ling Yuan Xiaofeng Shen Xuejiao Liao Jigang Wang Haoyu Hu Zhihai Huang Li Xiang Shilin Chen | 2022 | Molecular Plant2022，15，8： | 1 |
| 14 | Applying plant DNA barcodes for Rosaceae species identification显示文摘 | PANG XH SONG JY ZHU YJ Linfang Huang and Shilin Chen | 2010 | Cladistics2010，26，： | 1 |
| 15 | Word sense disambiguation based on positional weighted context显示文摘 | Huang Shilin Zheng Xiaolin Kang Haixiao | 2013 | Journal of Information Science2013，39，2： | 1 |
| 16 | Research on automobileairbag system显示文摘 | Zhang Jinhuan Wang Xiaodong Huang Shilin | 1997 | Journal of Tsinghua University1997，37，11： | 1 |
| 17 | Analysis of lithofacies and evaluation of effective reservoirs of member 2 of Xujiahe Formation in the Xinchang area in Western Sichuan显示文摘In the Xinchang area in western Sichuan Basin,a total of 121.12 billion cubic meters of proved reserves of natural gas are discovered in Member 2 of Xujiahe Formation,but only 7.739 billion cubic meters of proved reserves of natural gas are produced.The main reason is that sandstones in Member 2 of Xujiahe Formation in the Xinchang area are generally tight,with strong heterogeneity,only intervals with relatively good physical properties have a certain production capacity;therefore,it is very necessary and important to evaluate effective reservoirs in Member 2 of Xujiahe Formation.Through analysis of cores,with consideration of color,sedimentary texture and grain size,lithofacies of Member 2 of Xujiahe Formation in the Xinchang area can be divided into 12 types.According to data of physical properties and thin section analysis,it can be concluded that the favorable lithofacies in the upper submember of Member 2 of Xujiahe Formation are the massive medium-coarse sandstone,the medium-coarse sandstone with cross bedding,and the medium-coarse sandstone with carbonaceous fragments.On the basis of electrical characteristics,well-logging interpretation standards for favorable lithofacies are established,in addition,favorable lithofacies and effective reservoir in the Xinchang area are determined,and distribution of favorable lithofacies(effective reservoir)is identified,which lay a solid foundation for next deployment of appraisal well and development of effective reserves. | Yanqing Huang Zhongqun Liu Pengwei Li Junlong Liu Changzhen Liao Shilin Xu | 2020 | Petroleum Research2020，5，3： | 1 |
| 18 | Mining physical protein-protein interactions from theliterature显示文摘 | HUANG Minlie DING Shilin WANG Hongning | 2008 | Genome Biology2008，9，2： | 1 |
| 19 | Structural Characteristics of Cellulose and Xylan during in vitro Fermentation by Pig Fecal Bacteria显示文摘In this study,cellulose and xylan were in vitro fermented by pig fecal bacteria.Rapid fermentation(40 h) and extended fermentation(eight weeks)were performed.The properties and ultra-structure changes of post-fermented solid residues were studied.In the end effluent,acetic acid,propionic acid,and butyric acid were observed to be the principal short-chain fatty acids(SCFAs) produced by anaerobic fermentation.Xylan was more accessible to bacteria than cellulose,leading to higher SCFA and lactic acid production.In addition,the crystalline structure of cellulose changed,leading to 16.3% and42.1% increases in crystallinity index for rapid and extended fermentation,respectively.Through this research,a systematic and advanced method to study the degradation chemistry of cellulose and xylan during fermentation was developed. | Ling Meng ShiLin Cao XiaoJuan Ma LiHui Chen LiuLian Huang Fang Huang | 2016 | Paper And Biomaterials2016，1，2： | 0 |
| 20 | Whether and When Superhydrophobic/Superoleophobic Surfaces Are Fingerprint Repellent显示文摘Driven by the ever-increasing demand for fingerprint-resistant techniques in modern society,numerous researches have proposed to develop innovative antifingerprint coatings based on superhydrophobic/superoleophobic surface design.However,whether superhydrophobic/superoleophobic surfaces have favorable repellency to the microscopic fingerprint is in fact an open question.Here,we establish a reliable method that enables evaluating the antifingerprint capability of various surfaces in a quantitative way.We show that superhydrophobicity is irrelevant with fingerprint repellency.Regarding superoleophobic surfaces,two distinct wetting states of microscopic fingerprint residues,i.e.,the'repellent'and the“collapsed”states,are revealed.Only in the'repellent'state,in which the fingerprint residues remain atop surface textures upon being pressed,superoleophobic surfaces can bring about favorable antifingerprint repellency,which correlates positively with their receding contact angles.A finger-deformation-dependent intrusion mechanism is proposed to account for the formation of diferent fingerprint wetting states.Our findings offer important insights into the mechanism of fingerprint repellency and will help the design of high-performance antifingerprint surfaces for diverse applications. | Chengjiao Wu Yue Fan Hongxin Wang Juan Li Yuxi Chen Yingke Wang Lin Liu Lidan Zhou Shilin Huang Xuelin Tian | 2023 | Research2023，，1： | 0 |
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