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| 1 | Olfactory ecto-mesenchymal stem cells possess immunoregulatory function and suppress autoimmune arthritis显示文摘最近的研究在嗅觉的薄板 propria 作为居民干细胞的一种新类型识别了嗅觉的 ecto 间充质的干细胞(OE-MSCs ) 。然而,它仍然保持不清楚是否 OE-MSCs 拥有任何 immunoregulatory 功能。在这研究,我们发现老鼠 OE-MSCs 比骨头表示了更高转变的生长因素贝它和 interleukin-10 层次导出髓的 MSC。在文化, OE-MSCs 经由直接压制受动器 T 房间增长并且增加规章的 T (Treg ) 房间扩大施加了他们的抑制免疫力的能力。在有导致骨胶原的关节炎的老鼠, OE-MSCs 的采纳转移显著地压制了关节炎发作和疾病严厉,它被增加的 Treg 房间伴随并且在 vivo 减少了 Th1/Th17 房间回答。一起拿,我们的调查结果在调整 T 房间回答识别了 OE-MSCs 的新奇功能,显示那 OE-MSCs 可以为风湿性关节炎和另外的自体免疫的疾病的处理代表新房间治疗。 | Ke Rui Zhijiang Zhang Jie Tian Xiang Lin Xiaohui Wang Jie Ma Xinyi Tang Huaxi Xu Liwei Lu Shengjun Wang | 2016 | Cellular & Molecular Immunology2016，13，3： | 8 |
| 2 | The Tibetan Plateau Surface–Atmosphere Coupling System and Its Weather and Climate Effects: The Third Tibetan Plateau Atmospheric Science Experiment显示文摘The Tibetan Plateau(TP) is a key area affecting forecasts of weather and climate in China and occurrences of extreme weather and climate events over the world. The China Meteorological Administration, the National Natural Science Foundation of China, and the Chinese Academy of Sciences jointly initiated the Third Tibetan Plateau Atmospheric Science Experiment(TIPEX-Ⅲ) in 2013, with an 8–10-yr implementation plan. Since its preliminary field measurements conducted in 2013, routine automatic sounding systems have been deployed at Shiquanhe, Gaize, and Shenzha stations in western TP, where no routine sounding observations were available previously. The observational networks for soil temperature and soil moisture in the central and western TP have also been established. Meanwhile, the plateau-scale and regional-scale boundary layer observations, cloud–precipitation microphysical observations with multiple radars and aircraft campaigns, and tropospheric–stratospheric air composition observations at multiple sites, were performed. The results so far show that the turbulent heat exchange coefficient and sensible heat flux are remarkably lower than the earlier estimations at grassland, meadow, and bare soil surfaces of the central and western TP. Climatologically, cumulus clouds over the main body of the TP might develop locally instead of originating from the cumulus clouds that propagate northward from South Asia. The TIPEX-Ⅲ observations up to now also reveal diurnal variations, macro-and microphysical characteristics, and water-phase transition mechanisms, of cumulus clouds at Naqu station. Moreover, TIPEX-Ⅲ related studies have proposed a maintenance mechanism responsible for the Asian 'atmospheric water tower' and demonstrated the effects of the TP heating anomalies on African, Asian, and North American climates. Additionally, numerical modeling studies show that the Γ distribution of raindrop size is more suitable for depicting the TP raindrop characteristics compared to the M–P distribution, the overestimation of sensible heat flux can be reduced via modifying the heat transfer parameterization over the TP, and considering climatic signals in some key areas of the TP can improve the skill for rainfall forecast in the central and eastern parts of China. Furthermore, the TIPEX-Ⅲ has been promoting the technology in processing surface observations, soundings, and radar observations, improving the quality of satellite retrieved soil moisture and atmospheric water vapor content products as well as high-resolution gauge–radar–satellite merged rainfall products, and facilitating the meteorological monitoring, forecasting, and data sharing operations. | Ping ZHAO Yueqing LI Xueliang GUO Xiangde XU Yimin LIU Shihao TANG Wenming XIAO Chunxiang SHI Yaoming MA Xing YU Huizhi LIU La JIA Yun CHEN Yanju LIU Jian LI Dabiao LUO Yunchang CAO Xiangdong ZHENG Junming CHEN An XIAO Fang YUAN Donghui CHEN Yang PANG Zhiqun HU Shengjun ZHANG Lixin DONG Juyang HU Shuai HAN Xiuji ZHOU | 2019 | Journal of Meteorological Research2019，33，3： | 4 |
| 3 | Correlation between the Frequency of Th17 Cell and the Expression of MicroRNA-206 in Patients with Dermatomyositis显示文摘 | Xinyi Tang Xinyu Tian Yue Zhang Wei Wu Jie Tian Ke Rui Jia Tong Liwei Lu Huaxi Xu Shengjun Wang E. Shevach | 2013 | Clinical and Developmental Immunology2013，，： | 1 |
| 4 | Uncertainty modeling of wind power frequency regulation potential considering distributed characteristics of forecast errors显示文摘Large-scale integration of wind power generation decreases the equivalent inertia of a power system, and thus makes frequency stability control challenging. However, given the irregular, nonlinear, and non-stationary characteristics of wind power, significant challenges arise in making wind power generation participate in system frequency regulation. Hence, it is important to explore wind power frequency regulation potential and its uncertainty. This paper proposes an innovative uncertainty modeling method based on mixed skew generalized error distribution for wind power frequency regulation potential. The mapping relationship between wind speed and the associated frequency regulation potential is established, and key parameters of the wind turbine model are identified to predict the wind power frequency regulation potential. Furthermore, the prediction error distribution of the frequency regulation potential is obtained from the mixed skew model. Because of the characteristics of error partition, the error distribution model and predicted values at different wind speed sections are summarized to generate the uncertainty interval of wind power frequency regulation potential. Numerical experiments demonstrate that the proposed model outperforms other state-of-the-art contrastive models in terms of the refined degree of fitting error distribution characteristics. The proposed model only requires the wind speed prediction sequence to accurately model the uncertainty interval. This should be of great significance for rationally optimizing system frequency regulation resources and reducing redundant backup. | Cheng Yan Yi Tang Jianfeng Dai Chenggen Wang Shengjun Wu | 2021 | Protection and Control of Modern Power Systems2021，6，1： | 1 |
| 5 | Heterologous mRNA vaccine booster increases neutralization of SARS-CoV-2 Omicron BA.2 variant显示文摘Dear Editor,Emerging epidemiology data indicate that the Omicron BA.2 sublineage is expected to become the dominant strain owing to its enhanced transmissibility.1 The BA.1 sublineage reduced the efficacy of neutralizing antibodies.2,3 The BA.2 sublineage may possess similar neutralizing antibody evasion.3 However,booster(3rd dose)vaccination strategies,or three exposures to the SARS-CoV2 spike protein through natural infection elicits strong neutralizing antibody responses.This raises the question of whether booster doses also elicit neutralizing antibody responses against BA.2.We present in this study the neutralization activity of serum from human recipients of homologous booster(three doses of CoronaVac inactivated vaccine)or heterologous booster(inactivated vaccine priming dose with BnT162b2 third dose)vaccine regimens against pseudovirus containing the Omicron BA.2 spike protein.We also evaluated the neutralizing activities of 6 monoclonal antibodies,and serum from monkeys vaccinated with a recombinant RBD protein vaccine.Finally,we also evaluated cell entry mediated by the Omicron BA.2 spike protein. | Gen Li Zhongcheng Zhou Peng Du Meixiao Zhan Ning Li Xinxin Xiong Shengjun Tang Miao Man Daniel T.Baptista-Hon Ligong Lu | 2022 | Signal Transduction and Targeted Therapy2022，7，8： | 0 |
| 6 | Identification of twist-angle-dependent excitons in WS^(2)/WSe_(2) heterobilayers显示文摘Stacking atomically thin films enables artificial construction of van der Waals heterostructures with exotic functionalities such as superconductivity,the quantum Hall effect,and engineered light-matter interactions.In particular,heterobilayers composed of monolayer transition metal dichalcogenides have attracted significant interest due to their controllable interlayer coupling and trapped valley excitons in moirésuperlattices.However,the identification of twist-angle-modulated optical transitions in heterobilayers is sometimes controversial since both momentum-direct(K–K)and-indirect excitons reside on the low energy side of the bright exciton in the monolayer constituents.Here,we attribute the optical transition at~1.35 eV in the WS_(2)/WSe_(2) heterobilayer to an indirectΓ–K transition based on a systematic analysis and comparison of experimental photoluminescence spectra with theoretical calculations.The exciton wavefunction obtained by the state-of-the-art GW-Bethe-Salpeter equation approach indicates that both the electron and hole of the excitons are contributed by the WS_(2) layer.Polarization-resolved k-space imaging further confirms that the transition dipole moment of this optical transition is dominantly in-plane and is independent of the twist angle.The calculated absorption spectrum predicts that the so-called interlayer exciton peak coming from the K–K transition is located at 1.06 eV,but with a much weaker amplitude.Our work provides new insight into the steady-state and dynamic properties of twist-angle-dependent excitons in van der Waals heterostructures. | Ke Wu Hongxia Zhong Quanbing Guo Jibo Tang Jing Zhang Lihua Qian Zhifeng Shi Chendong Zhang Shengjun Yuan Shunping Zhang Hongxing Xu | 2022 | National Science Review2022，9，6： | 0 |
| 7 | An isoleucine-zipper motif enhances costimulation of human soluble trimeric GITR ligand显示文摘Glucocorticoid-induced tumor-necrosis factor receptor(GITR)and its ligand,GITRL,play significant roles in regulating immune responses.It is clear that human soluble GITRL(hsGITRL)transduces signal activity through multiple oligomerization states.To develop human soluble trimeric GITRL protein as a potential therapeutic target,we explored the link of the isoleucine-zipper(ILZ)motif to the N-terminus of the human soluble GITRL with two leucine sequences.hsGITRL,with the ILZ motif(ILZ-hsGITRL),was firstly expressed in Escherichia coli,which exhibited a predominant trimer when identified by Sephadex G-100 filtration and non-reducing SDS–polyacrylamide gel electrophoresis(SDS-PAGE).The significantly higher biological activity of the ILZ-hsGITRL compared with hsGITRL was confirmed by CD41 T proliferation,interferon-c(IFN-c)secretion and binding activity assay.To reveal and compare the underlying mechanisms,the level of extracellular signal-regulated kinase-1/2(ERK1/2)phosphorylation was examined,indicating that ILZ-hsGITRL induced more persistent and stronger ERK1/2 activation than hsGITRL.In conclusion,the incorporation of an ILZ motif could markedly improve the costimulation of hsGITRL. | Dawei Cui Shengjun Wang Yu Chen Jia Tong Jie Ma Li Tang Xianzhi Yang Ye Shi Jie Tian Liwei Lu Huaxi Xu | 2010 | Cellular & Molecular Immunology2010，7，4： | 0 |
| 8 | An amorphous FeMoO_(4) nanorod array enabled high-efficiency oxygen evolution electrocatalysis in alkaline seawater显示文摘The development of highly efficient and durable oxygen evolution reaction(OER)catalysts for seawater electrolysis is of great importance for applications.Here,an amorphous FeMoO_(4) nanorod array on Ni foam is reported as a highly active OER electrocatalyst in alkaline seawater,requiring only overpotentials of 303 and 332 mV to achieve 100 and 300 mA·cm^(-2),respectively.Moreover,it shows strong long-term electrochemical durability for at least 50 h. | Jie Tang Shengjun Sun Xun He Hui Zhang Chaoxin Yang Min Zhang Meng Yue Hefeng Wang Yuntong Sun Yonglan Luo Sulaiman Alfaifi Asmaa Farouk Mohamed S.Hamdy Xuping Sun Huiqing Wang Binwu Ying | 2024 | Nano Research2024，17，4： | 0 |
| 9 | A survey on indoor 3D modeling and applications via RGB-D devices显示文摘With the fast development of consumer-level RGB-D cameras, real-world indoor three-dimensional(3 D) scene modeling and robotic applications are gaining more attention. However, indoor 3 D scene modeling is still challenging because the structure of interior objects may be complex and the RGB-D data acquired by consumer-level sensors may have poor quality. There is a lot of research in this area. In this survey, we provide an overview of recent advances in indoor scene modeling methods, public indoor datasets and libraries which can facilitate experiments and evaluations, and some typical applications using RGB-D devices including indoor localization and emergency evacuation. | Zhilu YUAN You LI Shengjun TANG Ming LI Renzhong GUO Weixi WANG | 2021 | Frontiers of Information Technology & Electronic Engineering2021，22，6： | 0 |
| 10 | Enhancing the stability of Ni Fe-layered double hydroxide nanosheet array for alkaline seawater oxidation by Ce doping显示文摘Electrocatalytic hydrogen production from seawater holds enormous promise for clean energy generation.Nevertheless,the direct electrolysis of seawater encounters significant challenges due to poor anodic stability caused by detrimental chlorine chemistry.Herein,we present our recent discovery that the incorporation of Ce into Ni Fe layered double hydroxide nanosheet array on Ni foam(Ce-Ni Fe LDH/NF)emerges as a robust electrocatalyst for seawater oxidation.During the seawater oxidation process,CeO_(2)is generated,effectively repelling Cl^(-)and inhibiting the formation of Cl O-,resulting in a notable enhancement in the oxidation activity and stability of alkaline seawater.The prepared Ce-Ni Fe LDH/NF requires only overpotential of 390 m V to achieve the current density of 1 A cm^(-2),while maintaining long-term stability for 500 h,outperforming the performance of Ni Fe LDH/NF(430 m V,150 h)by a significant margin.This study highlights the effectiveness of a Ce-doping strategy in augmenting the activity and stability of materials based on Ni Fe LDH in seawater electrolysis for oxygen evolution. | Yongchao Yao Shengjun Sun Hui Zhang Zixiao Li Chaoxin Yang Zhengwei Cai Xun He Kai Dong Yonglan Luo Yan Wang Yuchun Ren Qian Liu Dongdong Zheng Weihua Zhuang Bo Tang Xuping Sun Wenchuang(Walter)Hu | 2024 | Journal of Energy Chemistry2024，91，4： | 0 |
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